CA2720264C - A membrane for supporting the growth of retinal pigmented epithelial cells - Google Patents

A membrane for supporting the growth of retinal pigmented epithelial cells Download PDF

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Publication number
CA2720264C
CA2720264C CA2720264A CA2720264A CA2720264C CA 2720264 C CA2720264 C CA 2720264C CA 2720264 A CA2720264 A CA 2720264A CA 2720264 A CA2720264 A CA 2720264A CA 2720264 C CA2720264 C CA 2720264C
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CA
Canada
Prior art keywords
membrane
cells
membrane according
pores
pigmented epithelial
Prior art date
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Active
Application number
CA2720264A
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English (en)
French (fr)
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CA2720264A1 (en
Inventor
Peter Coffey
Lyndon Da Cruz
Karen Cheetham
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UCL Business Ltd
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UCL Business Ltd
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Publication of CA2720264A1 publication Critical patent/CA2720264A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2720264A 2008-04-14 2009-04-08 A membrane for supporting the growth of retinal pigmented epithelial cells Active CA2720264C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0806746.4 2008-04-14
GBGB0806746.4A GB0806746D0 (en) 2008-04-14 2008-04-14 Membrane
PCT/GB2009/000917 WO2009127809A1 (en) 2008-04-14 2009-04-08 Membrane

Publications (2)

Publication Number Publication Date
CA2720264A1 CA2720264A1 (en) 2009-10-22
CA2720264C true CA2720264C (en) 2016-09-27

Family

ID=39433610

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2720264A Active CA2720264C (en) 2008-04-14 2009-04-08 A membrane for supporting the growth of retinal pigmented epithelial cells

Country Status (19)

Country Link
US (2) US8642072B2 (cg-RX-API-DMAC10.html)
EP (1) EP2265711B1 (cg-RX-API-DMAC10.html)
JP (1) JP5552478B2 (cg-RX-API-DMAC10.html)
KR (2) KR101317094B1 (cg-RX-API-DMAC10.html)
CN (1) CN102016009B (cg-RX-API-DMAC10.html)
AU (1) AU2009237462B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0910936A2 (cg-RX-API-DMAC10.html)
CA (1) CA2720264C (cg-RX-API-DMAC10.html)
CO (1) CO6311115A2 (cg-RX-API-DMAC10.html)
DK (1) DK2265711T3 (cg-RX-API-DMAC10.html)
ES (1) ES2665284T3 (cg-RX-API-DMAC10.html)
GB (1) GB0806746D0 (cg-RX-API-DMAC10.html)
IL (1) IL208745A (cg-RX-API-DMAC10.html)
MX (1) MX2010011232A (cg-RX-API-DMAC10.html)
MY (1) MY159049A (cg-RX-API-DMAC10.html)
NZ (1) NZ587753A (cg-RX-API-DMAC10.html)
RU (1) RU2530169C2 (cg-RX-API-DMAC10.html)
WO (1) WO2009127809A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201006326B (cg-RX-API-DMAC10.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110112101A1 (en) * 2009-03-05 2011-05-12 Sanofi-Aventis Treatment for ocular-related disorders
WO2011142364A1 (ja) * 2010-05-10 2011-11-17 独立行政法人理化学研究所 細胞シート作製方法
AU2011279250B2 (en) 2010-07-12 2014-12-04 California Institute Of Technology Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same
BR112013021514A2 (pt) * 2011-02-25 2020-09-29 Riken método de produção de camada de célula epitelial de pigmento retinal
WO2012149468A2 (en) 2011-04-29 2012-11-01 University Of Southern California Instruments and methods for the implantation of cell-seeded substrates
US8877489B2 (en) 2011-12-05 2014-11-04 California Institute Of Technology Ultrathin parylene-C semipermeable membranes for biomedical applications
WO2012177968A1 (en) * 2011-06-22 2012-12-27 The Schepens Eye Research Institute, Inc. A scaffold for subretinal cell transplantation and drug delivery
JP6240596B2 (ja) 2011-07-11 2017-11-29 イアー サイエンス インスティテュート オーストラリア 鼓膜修復のためのデバイス
CN103007355B (zh) * 2011-09-20 2014-08-13 同济大学 一种水凝胶-纳米纤维膜及其制备方法和用途
CA2792081C (en) * 2011-10-11 2020-10-27 Bond University Ltd Layered compositions comprising 3d nanofibre webbing for tissue repair
IL287381B2 (en) 2011-11-14 2024-04-01 Astellas Inst For Regenerative Medicine Pharmaceutical preparations of human rpe cells and uses thereof
US9248013B2 (en) 2011-12-05 2016-02-02 California Institute Of Technology 3-Dimensional parylene scaffold cage
US20130330825A1 (en) * 2012-06-07 2013-12-12 City Of Hope Attachment substrates for directed differentiation of human embryonic stem cells in culture
US11033586B2 (en) 2012-08-24 2021-06-15 Riken Method for producing retinal pigment epithelial cell sheet
RU2518972C1 (ru) * 2012-12-24 2014-06-10 Общество с ограниченной ответственностью "НАНО КАСКАД" Трековая мембрана для фильтрации крови
AU2014363032A1 (en) 2013-12-11 2016-06-09 Pfizer Limited Method for producing retinal pigment epithelial cells
CN105013010B (zh) * 2015-07-07 2018-01-12 中山大学中山眼科中心 一种辅助iPS‑RPE移植的层粘连蛋白膜
CN105597145A (zh) * 2016-02-22 2016-05-25 中山大学中山眼科中心 一种视网膜细胞支架生物手术粘合剂及其制备方法
US20210230526A1 (en) * 2016-06-28 2021-07-29 National Agriculture And Food Research Organization Cell enclosure device and use for same
JP7669266B2 (ja) 2018-08-31 2025-04-28 ウィスコンシン アラムニ リサーチ ファンデーション 動脈内皮細胞を播種した血管移植片の生成
WO2020218480A1 (ja) 2019-04-26 2020-10-29 国立研究開発法人理化学研究所 神経網膜と網膜色素上皮細胞とハイドロゲルとを含む複合体及びその製造方法
RU2704094C1 (ru) * 2019-05-16 2019-10-23 федеральное государственное автономное учреждение "Национальный медицинский исследовательский центр "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ трансплантации ретинального пигментного эпителия в форме многоклеточных 3D сфероидов в эксперименте
JP2021141877A (ja) * 2020-03-13 2021-09-24 大日本印刷株式会社 細胞培養基材、細胞付細胞培養基材、細胞培養容器、細胞付細胞培養容器、上皮細胞シート及びその製造方法、被験物質の評価方法並びに評価キット
JP7676135B2 (ja) * 2020-12-14 2025-05-14 日本バイリーン株式会社 細胞培養担体
WO2025121055A1 (ja) 2023-12-06 2025-06-12 富士フイルム株式会社 培養容器及び培養容器の製造方法

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GB0118984D0 (en) * 2001-08-03 2001-09-26 Intercytex Ltd Fusion of cells
CN1739813A (zh) * 2005-09-15 2006-03-01 上海赐人合元企业发展有限公司 组织工程表皮替代物及其制备方法
KR100901343B1 (ko) 2007-07-23 2009-06-05 (주)실리콘화일 결정질 반도체 박막 제조 방법
RU2368359C1 (ru) * 2008-07-22 2009-09-27 Государственное учреждение "УФИМСКИЙ НАУЧНО-ИССЛЕДОВАТЕЛЬСКИЙ ИНСТИТУТ ГЛАЗНЫХ БОЛЕЗНЕЙ" Академии наук Республики Башкортостан (УфНИИ ГБ АН РБ) Способ лечения возрастной макулярной дегенерации

Also Published As

Publication number Publication date
EP2265711B1 (en) 2018-03-07
AU2009237462B2 (en) 2012-12-20
US8642072B2 (en) 2014-02-04
US8889179B2 (en) 2014-11-18
KR20100128329A (ko) 2010-12-07
RU2530169C2 (ru) 2014-10-10
CA2720264A1 (en) 2009-10-22
ES2665284T3 (es) 2018-04-25
JP2011517696A (ja) 2011-06-16
KR20130065737A (ko) 2013-06-19
RU2010144399A (ru) 2012-05-20
NZ587753A (en) 2012-07-27
IL208745A (en) 2015-04-30
WO2009127809A1 (en) 2009-10-22
CN102016009A (zh) 2011-04-13
GB0806746D0 (en) 2008-05-14
KR101317094B1 (ko) 2013-10-16
US20140127282A1 (en) 2014-05-08
AU2009237462A1 (en) 2009-10-22
BRPI0910936A2 (pt) 2015-10-06
ZA201006326B (en) 2011-09-28
US20110236464A1 (en) 2011-09-29
MY159049A (en) 2016-12-15
DK2265711T3 (en) 2018-04-30
IL208745A0 (en) 2010-12-30
MX2010011232A (es) 2011-02-23
CO6311115A2 (es) 2011-08-22
CN102016009B (zh) 2015-05-20
JP5552478B2 (ja) 2014-07-16
EP2265711A1 (en) 2010-12-29

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