CA2712512C - Use of serine protease inhibitors in the treatment of skin diseases - Google Patents
Use of serine protease inhibitors in the treatment of skin diseases Download PDFInfo
- Publication number
- CA2712512C CA2712512C CA2712512A CA2712512A CA2712512C CA 2712512 C CA2712512 C CA 2712512C CA 2712512 A CA2712512 A CA 2712512A CA 2712512 A CA2712512 A CA 2712512A CA 2712512 C CA2712512 C CA 2712512C
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- kallikrein
- serine protease
- protease inhibitor
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| US61/006,576 | 2008-01-22 | ||
| PCT/IB2009/000089 WO2009093119A2 (en) | 2008-01-21 | 2009-01-21 | Use of serine protease inhibitors in the treatment of skin diseases |
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| CN101977626A (zh) | 2008-01-21 | 2011-02-16 | 德莫迪斯公司 | 丝氨酸蛋白酶抑制剂在治疗皮肤病中的用途 |
| WO2010103475A2 (en) * | 2009-03-10 | 2010-09-16 | Med Discovery Sa | Use of serine protease inhibitors in the treatment of neutropenia |
| KR101979464B1 (ko) | 2011-12-09 | 2019-05-16 | 모멘티브 파포만스 마테리아루즈 쟈판 고도가이샤 | 실리콘 고무 발포체용 조성물, 실리콘 고무 발포체의 제조방법 및 실리콘 고무 발포체 |
| TW201410709A (zh) * | 2012-08-08 | 2014-03-16 | Daiichi Sankyo Co Ltd | 肽庫及其利用 |
| US9815878B2 (en) | 2012-09-19 | 2017-11-14 | Mackay Memorial Hospital | Use of PEDF-derived polypeptides for preventing and/or ameliorating skin aging |
| KR101437408B1 (ko) | 2012-11-05 | 2014-09-05 | 동아대학교 산학협력단 | 플라스민 및 엘라스타아제 저해 활성을 갖는 산왕거미 유래의 쿠니츠 타입 세린 프로테아제 저해 단백질 및 이를 유효성분으로 포함하는 염증 억제 및 항섬유소용해용 조성물 |
| US10807805B2 (en) | 2013-05-17 | 2020-10-20 | Intelligrated Headquarters, Llc | Robotic carton unloader |
| CN105473474B (zh) | 2013-05-17 | 2018-01-23 | 因特利格兰特总部有限责任公司 | 机器人纸箱卸载机 |
| GB201322091D0 (en) * | 2013-12-13 | 2014-01-29 | Cambridge Entpr Ltd | Modified serpins for the treatment of bleeding disorders |
| WO2015114144A1 (en) * | 2014-02-03 | 2015-08-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of netherton syndrome |
| JP6608382B2 (ja) * | 2014-02-26 | 2019-11-20 | ルマ セラピューティクス，インク． | 紫外光治療装置及び方法 |
| JP6738280B2 (ja) * | 2014-10-24 | 2020-08-12 | 株式会社 資生堂 | 角層剥離の抑制又は亢進に起因する肌状態を改善するための美容方法及び評価方法 |
| MA40998A (fr) | 2014-11-21 | 2017-09-26 | Ophirex Inc | Thérapies contre une envenimation, ainsi que compositions, systèmes et kits pharmaceutiques associés |
| US10597235B2 (en) | 2016-10-20 | 2020-03-24 | Intelligrated Headquarters, Llc | Carton unloader tool for jam recovery |
| CN106478812B (zh) * | 2016-10-21 | 2020-11-20 | 沈阳药科大学 | 丝氨酸蛋白酶抑制剂-3及其功能、制备方法和应用 |
| TW202313978A (zh) * | 2016-11-23 | 2023-04-01 | 美商阿尼拉製藥公司 | 絲胺酸蛋白酶抑制因子Ａ１ ｉＲＮＡ組成物及其使用方法 |
| EP3624820A1 (en) * | 2017-04-21 | 2020-03-25 | H. Hoffnabb-La Roche Ag | Use of klk5 antagonists for treatment of a disease |
| CA3067364A1 (en) * | 2017-06-16 | 2018-12-20 | Azitra Inc | Compositions and methods for treatment of netherton syndrome with lekti expressing recombinant microbes |
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| JP7562515B2 (ja) * | 2018-09-24 | 2024-10-07 | クリスタル バイオテック インコーポレイテッド | ネザートン症候群の治療のための組成物及び方法 |
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| WO2021102176A2 (en) * | 2019-11-21 | 2021-05-27 | The Regents Of The University Of Michigan | Polypeptide inhibitors of neutrophil elastase activity and uses thereof |
| EP4114414A4 (en) * | 2020-03-06 | 2024-03-27 | The Regents of The University of Michigan | Serine protease inhibitors for suppressing or preventing anaphylactic reaction |
| CN112315897A (zh) * | 2020-11-04 | 2021-02-05 | 深圳前海鹰岗生物科技有限公司 | 一种抑制细胞炎症反应释放治疗痛风急性发作的聚合物微针及制备方法 |
| EP4466008A4 (en) * | 2022-01-18 | 2025-08-20 | Univ California | METHOD FOR INHIBITING PROTEASE ACTIVITY IN DEGRADATION DURING AGING |
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| CN117084936A (zh) * | 2023-09-22 | 2023-11-21 | 南京盛德生物科技研究院有限公司 | 多萜类化合物作为激肽释放酶抑制剂在化妆品中的应用 |
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| US5079336A (en) * | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| US5252725A (en) * | 1989-06-23 | 1993-10-12 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
| DE4214215A1 (de) * | 1992-04-30 | 1993-11-04 | Behringwerke Ag | Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen |
| AUPP508798A0 (en) * | 1998-08-05 | 1998-08-27 | Biotech Australia Pty Limited | Method of treating psoriasis |
| PT1202743E (pt) * | 1999-06-18 | 2005-02-28 | Jon Bragi Bjarnason | Composicoes farmaceuticas e cosmeticas compreendendo serina-proteases de bacalhau e sua utilizacao farmaceutica e cosmetica |
| US7105172B1 (en) * | 1999-11-18 | 2006-09-12 | Bolla John D | Treatment of rosacea |
| EP1334179A2 (en) * | 2000-11-14 | 2003-08-13 | Bristol-Myers Squibb Company | A human serpin secreted from lymphoid cells lsi-01 |
| JP2006508971A (ja) * | 2002-11-20 | 2006-03-16 | アライバ−プロメティック インコーポレイティド | プロテアーゼ阻害剤を使用して炎症性疾患を治療する組成物及び方法 |
| US20040097481A1 (en) * | 2002-11-20 | 2004-05-20 | Benjamin Levinson | Water-soluble mesoporphyrin compounds and methods of preparation |
| CN1798838B (zh) * | 2003-04-04 | 2012-01-04 | 洛桑大学 | 一种蛋白酶的抑制剂蛋白及其用途 |
| WO2005117955A1 (en) * | 2004-05-19 | 2005-12-15 | Arriva Pharmaceuticals, Inc. | Treatment of atopic dermatitis with unglycosylated alpha one-antitrypsin |
| EP1666075A1 (en) * | 2004-10-04 | 2006-06-07 | Switch Biotech Aktiengesellschaft | Wound dressing compositions, especially for delivery of protease inhibitors |
| WO2006090282A2 (en) * | 2005-02-28 | 2006-08-31 | Universite De Lausanne | Recombinant inhibitor proteins of an hk14 protease and use thereof |
| GB0525999D0 (en) * | 2005-12-21 | 2006-02-01 | Ares Trading Sa | Novel members of the kazal family of serine protease inhibitors |
| UA98647C2 (en) * | 2007-06-28 | 2012-06-11 | Новартис Аг | Kallikrein-7 modulators |
| JP5401459B2 (ja) * | 2007-08-17 | 2014-01-29 | ノバルティス アーゲー | カリクレイン７を阻害するための環状デプシペプチドの使用 |
| CN101977626A (zh) | 2008-01-21 | 2011-02-16 | 德莫迪斯公司 | 丝氨酸蛋白酶抑制剂在治疗皮肤病中的用途 |
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| WO2009093119A2 (en) | 2009-07-30 |
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| JP5891266B2 (ja) | 2016-03-22 |
| AU2009207394B2 (en) | 2015-01-22 |
| US11793864B2 (en) | 2023-10-24 |
| CN101977626A (zh) | 2011-02-16 |
| JP2011511766A (ja) | 2011-04-14 |
| CA2712512A1 (en) | 2009-07-30 |
| CN110522905A (zh) | 2019-12-03 |
| JP5615184B2 (ja) | 2014-10-29 |
| US20190183989A1 (en) | 2019-06-20 |
| AU2009207394A1 (en) | 2009-07-30 |
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