CA2694475C - Quinazolinamide derivatives - Google Patents
Quinazolinamide derivatives Download PDFInfo
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- CA2694475C CA2694475C CA2694475A CA2694475A CA2694475C CA 2694475 C CA2694475 C CA 2694475C CA 2694475 A CA2694475 A CA 2694475A CA 2694475 A CA2694475 A CA 2694475A CA 2694475 C CA2694475 C CA 2694475C
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007032739.2 | 2007-07-13 | ||
| DE102007032739A DE102007032739A1 (de) | 2007-07-13 | 2007-07-13 | Chinazolinamidderivate |
| PCT/EP2008/004846 WO2009010139A2 (de) | 2007-07-13 | 2008-06-16 | Chinazolinamidderivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2694475A1 CA2694475A1 (en) | 2009-01-22 |
| CA2694475C true CA2694475C (en) | 2015-07-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2694475A Expired - Fee Related CA2694475C (en) | 2007-07-13 | 2008-06-16 | Quinazolinamide derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8501754B2 (enExample) |
| EP (1) | EP2164833B1 (enExample) |
| JP (1) | JP5457343B2 (enExample) |
| KR (1) | KR20100044846A (enExample) |
| CN (1) | CN101743229B (enExample) |
| AR (1) | AR067506A1 (enExample) |
| AU (1) | AU2008278032B2 (enExample) |
| BR (1) | BRPI0814236A2 (enExample) |
| CA (1) | CA2694475C (enExample) |
| DE (1) | DE102007032739A1 (enExample) |
| EA (1) | EA017585B1 (enExample) |
| ES (1) | ES2538218T3 (enExample) |
| IL (1) | IL203206A (enExample) |
| WO (1) | WO2009010139A2 (enExample) |
| ZA (1) | ZA201001058B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008061214A1 (de) * | 2008-12-09 | 2010-06-10 | Merck Patent Gmbh | Chinazolinamidderivate |
| AR077405A1 (es) | 2009-07-10 | 2011-08-24 | Sanofi Aventis | Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer |
| FR2949467B1 (fr) | 2009-09-03 | 2011-11-25 | Sanofi Aventis | Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation |
| CN102711749A (zh) * | 2009-11-05 | 2012-10-03 | 莱西肯医药有限公司 | 用于癌症治疗的色氨酸羟化酶抑制剂 |
| DE102009054302A1 (de) * | 2009-11-23 | 2011-05-26 | Merck Patent Gmbh | Chinazolinderivate |
| DE102010046837A1 (de) | 2010-09-29 | 2012-03-29 | Merck Patent Gmbh | Phenylchinazolinderivate |
| LT2643313T (lt) | 2010-11-24 | 2016-10-25 | Merck Patent Gmbh | Chinazolino karboksamido azetidinai |
| GB2486631A (en) * | 2010-12-01 | 2012-06-27 | Univ Sheffield | Phenol/quinone boronic acids/esters and method of preparation thereof |
| TW201311149A (zh) * | 2011-06-24 | 2013-03-16 | Ishihara Sangyo Kaisha | 有害生物防治劑 |
| WO2014143960A1 (en) * | 2013-03-15 | 2014-09-18 | Rexahn Pharmaceuticals, Inc. | Tetrahydroisoquinolin-2-yl-(quinazolin-4-yl) methanone compounds as cancer cell growth inhibitors |
| EP3253390B1 (en) | 2015-02-06 | 2022-04-13 | Merck Sharp & Dohme Corp. | Aminoquinazoline compounds as a2a antagonist |
| EP3317278B1 (en) * | 2015-07-01 | 2021-04-14 | Crinetics Pharmaceuticals, Inc. | Somatostatin modulators and uses thereof |
| JP6740354B2 (ja) | 2015-10-05 | 2020-08-12 | ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク | オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法 |
| TWI734806B (zh) * | 2016-07-19 | 2021-08-01 | 日商日本化藥股份有限公司 | 攝像元件用光電變換元件用材料及含有該材料之光電變換元件 |
| AU2018290511B2 (en) * | 2017-06-26 | 2022-01-27 | Sunshine Lake Pharma Co., Ltd. | Dihydropyrimidine compounds and uses thereof in medicine |
| CN107382976A (zh) * | 2017-07-04 | 2017-11-24 | 孙秀芹 | 一种治疗盆腔炎的化合物及制备方法和应用 |
| CN107488168A (zh) * | 2017-07-18 | 2017-12-19 | 黄绍菊 | 一种治疗盆腔炎的化合物及制备方法和应用 |
| EP3658560A4 (en) | 2017-07-25 | 2021-01-06 | Crinetics Pharmaceuticals, Inc. | SOMATOSTAT IN MODULATORS AND USES THEREOF |
| TWI853814B (zh) | 2018-05-31 | 2024-09-01 | 南韓商Ｃ＆Ｃ新藥研究所 | 雜環衍生物及其用途 |
| US20230250088A1 (en) * | 2020-07-15 | 2023-08-10 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| IL310724A (en) | 2021-08-10 | 2024-04-01 | Ifm Due Inc | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH STING ACTIVITY |
| WO2023244713A1 (en) * | 2022-06-16 | 2023-12-21 | Ensem Therapeutics, Inc. | Quinazoline derivatives, compositions and methods thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968921A (en) | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| AU3378599A (en) | 1998-04-03 | 1999-10-25 | University Of Pittsburgh | Benzoquinoid ansamycins for the treatment of cardiac arrest and stroke |
| EP1161231A2 (en) | 1999-03-12 | 2001-12-12 | THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH | Method of inhibiting a chaperone protein |
| CA2429196A1 (en) | 2000-03-24 | 2001-10-04 | Duke University | Characterization of grp94-ligand interactions and purification, screening, and therapeutic methods relating thereto |
| AU2001271567A1 (en) | 2000-06-29 | 2002-01-14 | Trustees Of Boston University | Use of geldanamycin and related compounds for prophylaxis or treatment of fibrogenic disorders |
| JP2004504356A (ja) | 2000-07-20 | 2004-02-12 | メルク エンド カムパニー インコーポレーテッド | Ｃ型肝炎ウイルスのプロセシングおよび複製の抑制 |
| ATE526019T1 (de) | 2000-07-28 | 2011-10-15 | Sloan Kettering Inst Cancer | Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen |
| CN1300116C (zh) | 2001-04-16 | 2007-02-14 | 卫材株式会社 | 1h－吲唑化合物 |
| EP1450784A4 (en) | 2001-11-09 | 2005-02-09 | Conforma Therapeutics Corp | HSP90-INHIBITABLE ZEARALANOL COMPOUNDS AND METHOD FOR THEIR PREPARATION AND USE |
| WO2006010595A1 (en) | 2004-07-27 | 2006-02-02 | Novartis Ag | Inhibitors of hsp90 |
| US20070054916A1 (en) * | 2004-10-01 | 2007-03-08 | Amgen Inc. | Aryl nitrogen-containing bicyclic compounds and methods of use |
| DE102005022977A1 (de) * | 2005-05-19 | 2006-12-07 | Merck Patent Gmbh | Phenylchinazolinderivate |
-
2007
- 2007-07-13 DE DE102007032739A patent/DE102007032739A1/de not_active Withdrawn
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2008
- 2008-06-16 ES ES08773474T patent/ES2538218T3/es active Active
- 2008-06-16 EP EP08773474.5A patent/EP2164833B1/de not_active Not-in-force
- 2008-06-16 EA EA201000098A patent/EA017585B1/ru not_active IP Right Cessation
- 2008-06-16 AU AU2008278032A patent/AU2008278032B2/en not_active Ceased
- 2008-06-16 CA CA2694475A patent/CA2694475C/en not_active Expired - Fee Related
- 2008-06-16 BR BRPI0814236-0A2A patent/BRPI0814236A2/pt not_active IP Right Cessation
- 2008-06-16 CN CN2008800245618A patent/CN101743229B/zh not_active Expired - Fee Related
- 2008-06-16 US US12/668,864 patent/US8501754B2/en not_active Expired - Fee Related
- 2008-06-16 WO PCT/EP2008/004846 patent/WO2009010139A2/de not_active Ceased
- 2008-06-16 JP JP2010515363A patent/JP5457343B2/ja not_active Expired - Fee Related
- 2008-06-16 KR KR1020107003221A patent/KR20100044846A/ko not_active Withdrawn
- 2008-07-11 AR ARP080102977A patent/AR067506A1/es unknown
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2010
- 2010-01-07 IL IL203206A patent/IL203206A/en not_active IP Right Cessation
- 2010-02-12 ZA ZA2010/01058A patent/ZA201001058B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101743229A (zh) | 2010-06-16 |
| US8501754B2 (en) | 2013-08-06 |
| IL203206A (en) | 2015-03-31 |
| AR067506A1 (es) | 2009-10-14 |
| BRPI0814236A2 (pt) | 2015-01-06 |
| AU2008278032A1 (en) | 2009-01-22 |
| DE102007032739A1 (de) | 2009-01-15 |
| KR20100044846A (ko) | 2010-04-30 |
| JP2010533132A (ja) | 2010-10-21 |
| US20100234324A1 (en) | 2010-09-16 |
| EP2164833A2 (de) | 2010-03-24 |
| WO2009010139A3 (de) | 2009-03-12 |
| ZA201001058B (en) | 2010-11-24 |
| AU2008278032B2 (en) | 2013-03-28 |
| EP2164833B1 (de) | 2015-04-15 |
| JP5457343B2 (ja) | 2014-04-02 |
| EA017585B1 (ru) | 2013-01-30 |
| EA201000098A1 (ru) | 2010-06-30 |
| ES2538218T3 (es) | 2015-06-18 |
| CN101743229B (zh) | 2013-08-14 |
| WO2009010139A2 (de) | 2009-01-22 |
| CA2694475A1 (en) | 2009-01-22 |
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| EEER | Examination request |
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| MKLA | Lapsed |
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