CA2689549A1 - Igf for the treatment of rett syndrome and synaptic disorders - Google Patents
Igf for the treatment of rett syndrome and synaptic disorders Download PDFInfo
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- CA2689549A1 CA2689549A1 CA002689549A CA2689549A CA2689549A1 CA 2689549 A1 CA2689549 A1 CA 2689549A1 CA 002689549 A CA002689549 A CA 002689549A CA 2689549 A CA2689549 A CA 2689549A CA 2689549 A1 CA2689549 A1 CA 2689549A1
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
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- Diabetes (AREA)
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- Zoology (AREA)
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- Immunology (AREA)
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- Psychology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
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| PCT/US2008/007107 WO2008153929A1 (en) | 2007-06-08 | 2008-06-06 | Igf for the treatment of rett syndrome and synaptic disorders |
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| CA2689549A1 true CA2689549A1 (en) | 2008-12-18 |
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| HUE025151T2 (en) | 2004-08-23 | 2016-01-28 | Mannkind Corp | Diceto-piperazine salts for drug delivery |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| US8969295B2 (en) * | 2006-04-14 | 2015-03-03 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| CN102348798A (zh) | 2009-01-16 | 2012-02-08 | 麻省理工学院 | 孤独症谱系障碍的诊断和治疗 |
| EP2571515B1 (en) | 2010-05-17 | 2016-11-30 | Icahn School of Medicine at Mount Sinai | Methods and assays for treating subjects with shank3 deletion, mutation or reduced expression |
| LT2667715T (lt) * | 2011-01-27 | 2017-11-10 | Neuren Pharmaceuticals Limited | Autizmo spektro susirgimų gydymas, naudojant glicil-l-2-metilprolil-l-glutamo rūgštį |
| MX353285B (es) * | 2011-04-01 | 2018-01-05 | Mannkind Corp | Paquete de blister para cartuchos farmaceuticos. |
| DK2734634T3 (da) * | 2011-07-22 | 2019-10-21 | Univ Chicago | Igf-1 til anvendelse til behandling af migræne |
| HK1201475A1 (en) | 2011-10-24 | 2015-09-04 | Mannkind Corporation | Methods and compositions for treating pain |
| WO2014085480A1 (en) * | 2012-11-28 | 2014-06-05 | Neuren Pharmaceuticals Limited | Treatment of autism spectrum disorders using glycyl-l-2-methylprolyl-l-glutamic acid |
| ES2495266B8 (es) * | 2013-02-13 | 2015-11-12 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de igf-1 como reactivo de diagnóstico y/o pronóstico precoz de la enfermedad de alzheimer |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| RU2017110868A (ru) | 2014-09-25 | 2018-10-25 | Колд Спринг Харбор Лаборатори | Лечение синдрома ретта |
| JP6866379B2 (ja) | 2016-01-26 | 2021-04-28 | アナベックス ライフ サイエンシズ コーポレイション | 神経発達障害療法 |
| TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
| WO2018217766A1 (en) | 2017-05-22 | 2018-11-29 | Whitehead Institute For Biomedical Research | Kcc2 expression enhancing compounds and uses thereof |
| CN108187031A (zh) * | 2018-02-11 | 2018-06-22 | 中国人民解放军第四军医大学 | rhIGF1在制备治疗脆性X综合征药物中的应用 |
| JP2022524927A (ja) | 2019-02-02 | 2022-05-11 | ステモニックス インコーポレイティド | 創薬のためのヒトスフェロイドの使用方法 |
| JP2022547948A (ja) | 2019-09-09 | 2022-11-16 | ザ・ユニバーシティ・オブ・シカゴ | 片頭痛の処置のための併用療法 |
| WO2021100614A1 (ja) * | 2019-11-19 | 2021-05-27 | 国立大学法人京都大学 | 大豆ペプチド及び／又はコラーゲンペプチド含有神経心理学的機能改善剤 |
| WO2022055045A1 (ko) * | 2020-09-08 | 2022-03-17 | 주식회사 선마린바이오테크 | 콜라게나제 저해 활성 펩타이드 유도체 및 이의 용도 |
| US20240148835A1 (en) * | 2021-01-28 | 2024-05-09 | University Of Florida Research Foundation, Incorporated | Treating disorders associated with dyrk1a dysfunction |
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| US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| IL71991A (en) | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| AU637316B2 (en) | 1988-01-28 | 1993-05-27 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| AU628322B2 (en) | 1988-01-28 | 1992-09-17 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| SE8803847A0 (sv) | 1988-10-27 | 1990-04-28 | Kabigen Ab | Neuromodulerande peptid |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| ES2101865T3 (es) | 1991-08-01 | 1997-07-16 | Genentech Inc | Igf-1 para mejorar el estado neural. |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| US5420112A (en) | 1992-06-12 | 1995-05-30 | Lewis; Michael E. | Prevention and treatment of peripheral neuropathy |
| US5446024A (en) | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
| CA2178711A1 (en) | 1993-12-23 | 1995-06-29 | Peter David Gluckman | Composition and methods to improve neural outcome |
| US5565428A (en) | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US20020132252A1 (en) | 1997-06-16 | 2002-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6358951B1 (en) | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| US7304029B1 (en) | 1998-09-03 | 2007-12-04 | Neuren Pharmaceuticals Ltd. | Neuroprotective effect of growth hormone |
| AU762351B2 (en) | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| WO2002016408A2 (en) | 2000-08-24 | 2002-02-28 | Neuronz Ltd. | Gpe analogs |
| WO2002057241A1 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES |
| WO2002056873A2 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues |
| DE60217066T4 (de) | 2001-02-09 | 2010-07-01 | Genentech, Inc., South San Francisco | Kristallisierung von igf-1 |
| US7863304B2 (en) | 2001-05-24 | 2011-01-04 | Neuren Pharmaceuticals Limited | Analogs of glycyl-prolyl-glutamate |
| EP1401808B1 (en) | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Gpe analogs and peptidomimetics |
| US7485630B2 (en) | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
| US20050027110A1 (en) | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
| DK2274978T3 (en) | 2003-09-12 | 2015-06-15 | Ipsen Biopharmaceuticals Inc | Methods of treating an insulin-like growth factor-I (IGF-I) deficiency |
| US20070224165A1 (en) | 2003-10-23 | 2007-09-27 | Neuren Pharmaceuticals Limited | Neuroprotective Effects of Gly-Pro-Glu Following Intravenous Infusion |
| US20060104969A1 (en) * | 2004-08-16 | 2006-05-18 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| JP2008511838A (ja) | 2004-08-30 | 2008-04-17 | テルシカ・インク | インシュリン様成長因子欠乏疾患の診断及び治療のための方法及び装置 |
| KR20060040550A (ko) | 2004-11-05 | 2006-05-10 | 마루이시세이야쿠가부시키가이샤 | 인슐린유사 성장인자-1 분비촉진제 |
| US8158582B2 (en) | 2005-06-02 | 2012-04-17 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-1 deficiency |
| US8969295B2 (en) * | 2006-04-14 | 2015-03-03 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
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- 2008-06-06 AU AU2008262387A patent/AU2008262387A1/en not_active Abandoned
- 2008-06-06 US US12/134,707 patent/US7994127B2/en active Active
- 2008-06-06 CA CA002689549A patent/CA2689549A1/en not_active Abandoned
- 2008-06-06 EP EP08768183A patent/EP2164509A1/en not_active Withdrawn
- 2008-06-06 WO PCT/US2008/007107 patent/WO2008153929A1/en not_active Ceased
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- 2008-06-06 CN CN200880024937A patent/CN101820896A/zh active Pending
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2011
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Also Published As
| Publication number | Publication date |
|---|---|
| CN101820896A (zh) | 2010-09-01 |
| EP2164509A1 (en) | 2010-03-24 |
| US7994127B2 (en) | 2011-08-09 |
| WO2008153929A1 (en) | 2008-12-18 |
| BRPI0812768A2 (pt) | 2014-12-02 |
| JP2010529128A (ja) | 2010-08-26 |
| AU2008262387A1 (en) | 2008-12-18 |
| US20120177630A1 (en) | 2012-07-12 |
| US20090099077A1 (en) | 2009-04-16 |
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Effective date: 20140606 |