CA2689549A1 - Igf for the treatment of rett syndrome and synaptic disorders - Google Patents
Igf for the treatment of rett syndrome and synaptic disorders Download PDFInfo
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- CA2689549A1 CA2689549A1 CA002689549A CA2689549A CA2689549A1 CA 2689549 A1 CA2689549 A1 CA 2689549A1 CA 002689549 A CA002689549 A CA 002689549A CA 2689549 A CA2689549 A CA 2689549A CA 2689549 A1 CA2689549 A1 CA 2689549A1
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
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- Diabetes (AREA)
- Molecular Biology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
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| US93373807P | 2007-06-08 | 2007-06-08 | |
| US60/933,738 | 2007-06-08 | ||
| PCT/US2008/007107 WO2008153929A1 (en) | 2007-06-08 | 2008-06-06 | Igf for the treatment of rett syndrome and synaptic disorders |
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| CA2689549A1 true CA2689549A1 (en) | 2008-12-18 |
Family
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| CA (1) | CA2689549A1 (enExample) |
| WO (1) | WO2008153929A1 (enExample) |
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| BRPI0514293B1 (pt) | 2004-08-23 | 2022-07-19 | Mannkind Corporation | Sistema microparticulado para distribuição de droga |
| DK1928423T3 (en) | 2005-09-14 | 2016-02-29 | Mannkind Corp | A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces |
| CA2650140A1 (en) * | 2006-04-14 | 2007-10-25 | Mriganka Sur | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8940732B2 (en) | 2009-01-16 | 2015-01-27 | Massachusetts Institute Of Technology | Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway |
| PT2571515T (pt) * | 2010-05-17 | 2017-03-02 | Icahn School Med Mount Sinai | Processos e ensaios para tratar indivíduos com eliminação, mutação ou expressão reduzida de shank3 |
| BR112013018898B1 (pt) * | 2011-01-27 | 2021-10-05 | Neuren Pharmaceuticals Limited | Uso de ácido glicil-l-2-metilprolil-l-glutâmico e análogos do mesmo para o tratamento de transtornos do espectro do autismo |
| MY180552A (en) * | 2011-04-01 | 2020-12-02 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| US9399053B2 (en) * | 2011-07-22 | 2016-07-26 | The University Of Chicago | Treatments for migraine and related disorders |
| JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
| WO2014085480A1 (en) * | 2012-11-28 | 2014-06-05 | Neuren Pharmaceuticals Limited | Treatment of autism spectrum disorders using glycyl-l-2-methylprolyl-l-glutamic acid |
| ES2495266B8 (es) * | 2013-02-13 | 2015-11-12 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de igf-1 como reactivo de diagnóstico y/o pronóstico precoz de la enfermedad de alzheimer |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| RU2017110868A (ru) | 2014-09-25 | 2018-10-25 | Колд Спринг Харбор Лаборатори | Лечение синдрома ретта |
| CA3012199C (en) | 2016-01-26 | 2024-05-07 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
| TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
| US11331313B2 (en) * | 2017-05-22 | 2022-05-17 | Whitehead Institute For Biomedical Research | KCC2 expression enhancing compounds and uses thereof |
| CN108187031A (zh) * | 2018-02-11 | 2018-06-22 | 中国人民解放军第四军医大学 | rhIGF1在制备治疗脆性X综合征药物中的应用 |
| JP2022547948A (ja) | 2019-09-09 | 2022-11-16 | ザ・ユニバーシティ・オブ・シカゴ | 片頭痛の処置のための併用療法 |
| JP7764992B2 (ja) * | 2019-11-19 | 2025-11-06 | 国立大学法人京都大学 | 大豆ペプチド及び／又はコラーゲンペプチド含有神経心理学的機能改善剤 |
| US20230312643A1 (en) * | 2020-09-08 | 2023-10-05 | Sunmarine Biotech | Peptide derivative with collagenase inhibitory activity, and use thereof |
| US20240148835A1 (en) * | 2021-01-28 | 2024-05-09 | University Of Florida Research Foundation, Incorporated | Treating disorders associated with dyrk1a dysfunction |
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| US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| IL71991A (en) | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| AU637316B2 (en) | 1988-01-28 | 1993-05-27 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| DE68919213T2 (de) | 1988-01-28 | 1995-05-11 | Polygen Holding Corp | Polypeptidverbindungen mit wachstumshormonfreisetzender aktivität. |
| SE8803847A0 (sv) * | 1988-10-27 | 1990-04-28 | Kabigen Ab | Neuromodulerande peptid |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| ATE151293T1 (de) | 1991-08-01 | 1997-04-15 | Genentech Inc | Igf-i zur verbesserung der neuronale lage |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| US5420112A (en) | 1992-06-12 | 1995-05-30 | Lewis; Michael E. | Prevention and treatment of peripheral neuropathy |
| US5446024A (en) | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
| JPH09509404A (ja) | 1993-12-23 | 1997-09-22 | オークランド ユニサービシズ リミテッド | 神経アウトカムを改良するための組成物及び方法 |
| US5565428A (en) | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US7074897B2 (en) | 1997-06-16 | 2006-07-11 | Genentech, Inc. | Pro943 polypeptides |
| US6358951B1 (en) | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| AU757907B2 (en) | 1998-09-03 | 2003-03-13 | Neuren Pharmaceuticals Limited | Neuroprotection |
| AU762351B2 (en) | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| AU2001289160A1 (en) | 2000-08-24 | 2002-03-04 | Neuronz Ltd. | Gpe analogs |
| WO2002057241A1 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES |
| WO2002056873A2 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues |
| CN100439397C (zh) | 2001-02-09 | 2008-12-03 | 基因技术股份有限公司 | Igf-1的结晶 |
| US7041314B2 (en) | 2001-05-24 | 2006-05-09 | Neuren Pharmaceuticals Ltd. | GPE analogs and peptidominetics |
| US7863304B2 (en) | 2001-05-24 | 2011-01-04 | Neuren Pharmaceuticals Limited | Analogs of glycyl-prolyl-glutamate |
| WO2004084809A2 (en) | 2003-03-20 | 2004-10-07 | Neuren Pharmaceuticals Ltd. | Neuroprotective macrocylic compounds and methods for their use |
| US20050027110A1 (en) * | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
| ES2373783T3 (es) | 2003-09-12 | 2012-02-08 | Tercica, Inc. | Métodos para el tratamiento de la deficiencia de factor 1 de crecimiento similar a la insulina (igf-1). |
| WO2005042000A1 (en) | 2003-10-23 | 2005-05-12 | Neuren Pharmaceuticals Limited | Neuroprotective effects of gly-pro-glu following intravenous infusion |
| US20060104969A1 (en) * | 2004-08-16 | 2006-05-18 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| ES2788699T3 (es) | 2004-08-30 | 2020-10-22 | Ipsen Biopharmaceuticals Inc | Procedimiento y dispositivo para diagnosticar y tratar trastornos de deficiencia del factor de crecimiento similar a la insulina |
| KR20060040550A (ko) | 2004-11-05 | 2006-05-10 | 마루이시세이야쿠가부시키가이샤 | 인슐린유사 성장인자-1 분비촉진제 |
| ES2532089T3 (es) | 2005-06-02 | 2015-03-24 | Ipsen Biopharmaceuticals, Inc. | GH e IGF-1 para el tratamiento de trastornos del crecimiento |
| CA2650140A1 (en) * | 2006-04-14 | 2007-10-25 | Mriganka Sur | Identifying and modulating molecular pathways that mediate nervous system plasticity |
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2008
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- 2008-06-06 CA CA002689549A patent/CA2689549A1/en not_active Abandoned
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- 2008-06-06 CN CN200880024937A patent/CN101820896A/zh active Pending
- 2008-06-06 AU AU2008262387A patent/AU2008262387A1/en not_active Abandoned
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2011
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Also Published As
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| AU2008262387A1 (en) | 2008-12-18 |
| EP2164509A1 (en) | 2010-03-24 |
| US20120177630A1 (en) | 2012-07-12 |
| BRPI0812768A2 (pt) | 2014-12-02 |
| WO2008153929A1 (en) | 2008-12-18 |
| US7994127B2 (en) | 2011-08-09 |
| US20090099077A1 (en) | 2009-04-16 |
| JP2010529128A (ja) | 2010-08-26 |
| CN101820896A (zh) | 2010-09-01 |
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