BRPI0812768A2 - Igf para o tratamento de síndrome de rett e transtornos sinápticos. - Google Patents
Igf para o tratamento de síndrome de rett e transtornos sinápticos.Info
- Publication number
- BRPI0812768A2 BRPI0812768A2 BRPI0812768-9A2A BRPI0812768A BRPI0812768A2 BR PI0812768 A2 BRPI0812768 A2 BR PI0812768A2 BR PI0812768 A BRPI0812768 A BR PI0812768A BR PI0812768 A2 BRPI0812768 A2 BR PI0812768A2
- Authority
- BR
- Brazil
- Prior art keywords
- igf
- treatment
- rett syndrome
- synaptic
- disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93373807P | 2007-06-08 | 2007-06-08 | |
| PCT/US2008/007107 WO2008153929A1 (en) | 2007-06-08 | 2008-06-06 | Igf for the treatment of rett syndrome and synaptic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0812768A2 true BRPI0812768A2 (pt) | 2014-12-02 |
Family
ID=39891784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812768-9A2A BRPI0812768A2 (pt) | 2007-06-08 | 2008-06-06 | Igf para o tratamento de síndrome de rett e transtornos sinápticos. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7994127B2 (enExample) |
| EP (1) | EP2164509A1 (enExample) |
| JP (1) | JP2010529128A (enExample) |
| CN (1) | CN101820896A (enExample) |
| AU (1) | AU2008262387A1 (enExample) |
| BR (1) | BRPI0812768A2 (enExample) |
| CA (1) | CA2689549A1 (enExample) |
| WO (1) | WO2008153929A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150039211A (ko) | 2004-08-23 | 2015-04-09 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| WO2007033372A2 (en) | 2005-09-14 | 2007-03-22 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
| CA2650140A1 (en) * | 2006-04-14 | 2007-10-25 | Mriganka Sur | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| JP2012515202A (ja) | 2009-01-16 | 2012-07-05 | マサチューセッツ インスティテュート オブ テクノロジー | 自閉症圏障害の診断および処置 |
| ES2617309T3 (es) | 2010-05-17 | 2017-06-16 | Icahn School Of Medicine At Mount Sinai | Métodos y ensayos de tratamiento de sujetos con eliminación, mutación o expresión reducida de SHANK3 |
| LT2667715T (lt) * | 2011-01-27 | 2017-11-10 | Neuren Pharmaceuticals Limited | Autizmo spektro susirgimų gydymas, naudojant glicil-l-2-metilprolil-l-glutamo rūgštį |
| CA3078334C (en) * | 2011-04-01 | 2022-08-09 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| EP2734634B1 (en) * | 2011-07-22 | 2019-08-21 | The University of Chicago | Igf-1 for use in the treatment of migraine |
| AU2012328885B2 (en) | 2011-10-24 | 2017-08-31 | Mannkind Corporation | Methods and compositions for treating pain |
| BR112015012506A2 (pt) * | 2012-11-28 | 2017-07-11 | Neuren Pharmaceuticals Ltd | tratamento de transtornos do espectro do autismo usando ácido glicil-l-2-metilprolil-l-glutâmico |
| ES2495266B8 (es) * | 2013-02-13 | 2015-11-12 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de igf-1 como reactivo de diagnóstico y/o pronóstico precoz de la enfermedad de alzheimer |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| MX2017003892A (es) | 2014-09-25 | 2018-01-30 | Cold Spring Harbor Laboratory | Tratamiento del sindrome de rett. |
| WO2017132127A1 (en) | 2016-01-26 | 2017-08-03 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
| TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
| WO2018217766A1 (en) * | 2017-05-22 | 2018-11-29 | Whitehead Institute For Biomedical Research | Kcc2 expression enhancing compounds and uses thereof |
| CN108187031A (zh) * | 2018-02-11 | 2018-06-22 | 中国人民解放军第四军医大学 | rhIGF1在制备治疗脆性X综合征药物中的应用 |
| CA3153776A1 (en) | 2019-09-09 | 2021-03-18 | The University Of Chicago | Combination therapy for the treatment of migraines |
| WO2021100614A1 (ja) * | 2019-11-19 | 2021-05-27 | 国立大学法人京都大学 | 大豆ペプチド及び/又はコラーゲンペプチド含有神経心理学的機能改善剤 |
| WO2022055045A1 (ko) * | 2020-09-08 | 2022-03-17 | 주식회사 선마린바이오테크 | 콜라게나제 저해 활성 펩타이드 유도체 및 이의 용도 |
| US20240148835A1 (en) * | 2021-01-28 | 2024-05-09 | University Of Florida Research Foundation, Incorporated | Treating disorders associated with dyrk1a dysfunction |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| IL71991A (en) * | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| WO1989007111A1 (en) | 1988-01-28 | 1989-08-10 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| AU637316B2 (en) | 1988-01-28 | 1993-05-27 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| SE8803847A0 (sv) | 1988-10-27 | 1990-04-28 | Kabigen Ab | Neuromodulerande peptid |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| CA2114251C (en) * | 1991-08-01 | 2007-11-06 | Peter Gluckman | Igf-1 to improve the neural condition |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| US5420112A (en) * | 1992-06-12 | 1995-05-30 | Lewis; Michael E. | Prevention and treatment of peripheral neuropathy |
| US5446024A (en) * | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
| EP0735894A4 (en) * | 1993-12-23 | 1999-08-18 | Auckland Uniservices Ltd | COMPOSITION AND METHODS FOR IMPROVING THE OUTCOME OF NERVOUS SYSTEM CONDITIONS |
| US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US20020132252A1 (en) * | 1997-06-16 | 2002-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6358951B1 (en) * | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| EP1109572A4 (en) * | 1998-09-03 | 2004-11-24 | Neuronz Ltd | NEUROPROTECTION |
| CA2356109C (en) * | 1999-01-06 | 2008-04-22 | Genentech, Inc. | Insulin-like growth factor (igf) i mutant variants |
| AU2001289160A1 (en) | 2000-08-24 | 2002-03-04 | Neuronz Ltd. | Gpe analogs |
| WO2002057241A1 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES |
| WO2002056873A2 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues |
| JP4489352B2 (ja) * | 2001-02-09 | 2010-06-23 | ジェネンテック, インコーポレイテッド | Igf−1の結晶化 |
| ES2325983T3 (es) * | 2001-05-24 | 2009-09-28 | Neuren Pharmaceuticals Limited | Analogos y peptidomimeticos de gpe. |
| US7863304B2 (en) * | 2001-05-24 | 2011-01-04 | Neuren Pharmaceuticals Limited | Analogs of glycyl-prolyl-glutamate |
| EP1648873A4 (en) * | 2003-03-20 | 2008-06-25 | Neuren Pharmaceuticals Ltd | NEUROPROTECTIVE MACROCYLIC COMPOUNDS AND METHODS OF THEIR APPLICATION |
| US20050027110A1 (en) | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
| EP1667521B1 (en) * | 2003-09-12 | 2011-12-07 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-1 (igf-1) deficiency |
| EP1684783A4 (en) * | 2003-10-23 | 2009-07-08 | Neuren Pharmaceuticals Ltd | NEUROPROTECTIVE EFFECTS OF GLY-PRO-GLU AFTER INTRAVENOUS INFUSION |
| WO2006023530A2 (en) * | 2004-08-16 | 2006-03-02 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| CN101022820A (zh) * | 2004-08-30 | 2007-08-22 | 特西卡股份有限公司 | 诊断和治疗胰岛素样生长因子缺陷疾病的方法和装置 |
| KR20060040550A (ko) * | 2004-11-05 | 2006-05-10 | 마루이시세이야쿠가부시키가이샤 | 인슐린유사 성장인자-1 분비촉진제 |
| EP1901770B1 (en) | 2005-06-02 | 2014-12-24 | Ipsen Biopharmaceuticals, Inc. | Gh and igf-1 for treatment of growth disorders |
| CA2650140A1 (en) * | 2006-04-14 | 2007-10-25 | Mriganka Sur | Identifying and modulating molecular pathways that mediate nervous system plasticity |
-
2008
- 2008-06-06 CA CA002689549A patent/CA2689549A1/en not_active Abandoned
- 2008-06-06 BR BRPI0812768-9A2A patent/BRPI0812768A2/pt not_active IP Right Cessation
- 2008-06-06 US US12/134,707 patent/US7994127B2/en active Active
- 2008-06-06 WO PCT/US2008/007107 patent/WO2008153929A1/en not_active Ceased
- 2008-06-06 JP JP2010511198A patent/JP2010529128A/ja active Pending
- 2008-06-06 EP EP08768183A patent/EP2164509A1/en not_active Withdrawn
- 2008-06-06 AU AU2008262387A patent/AU2008262387A1/en not_active Abandoned
- 2008-06-06 CN CN200880024937A patent/CN101820896A/zh active Pending
-
2011
- 2011-08-08 US US13/204,817 patent/US20120177630A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090099077A1 (en) | 2009-04-16 |
| EP2164509A1 (en) | 2010-03-24 |
| AU2008262387A1 (en) | 2008-12-18 |
| CA2689549A1 (en) | 2008-12-18 |
| WO2008153929A1 (en) | 2008-12-18 |
| CN101820896A (zh) | 2010-09-01 |
| US20120177630A1 (en) | 2012-07-12 |
| JP2010529128A (ja) | 2010-08-26 |
| US7994127B2 (en) | 2011-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |