PT2571515T - Processos e ensaios para tratar indivíduos com eliminação, mutação ou expressão reduzida de shank3 - Google Patents
Processos e ensaios para tratar indivíduos com eliminação, mutação ou expressão reduzida de shank3Info
- Publication number
- PT2571515T PT2571515T PT117838557T PT11783855T PT2571515T PT 2571515 T PT2571515 T PT 2571515T PT 117838557 T PT117838557 T PT 117838557T PT 11783855 T PT11783855 T PT 11783855T PT 2571515 T PT2571515 T PT 2571515T
- Authority
- PT
- Portugal
- Prior art keywords
- mutation
- assays
- methods
- reduced expression
- treating subjects
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39577510P | 2010-05-17 | 2010-05-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2571515T true PT2571515T (pt) | 2017-03-02 |
Family
ID=44992247
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT117838557T PT2571515T (pt) | 2010-05-17 | 2011-05-16 | Processos e ensaios para tratar indivíduos com eliminação, mutação ou expressão reduzida de shank3 |
Country Status (5)
Country | Link |
---|---|
US (3) | US8691762B2 (pt) |
EP (1) | EP2571515B1 (pt) |
ES (1) | ES2617309T3 (pt) |
PT (1) | PT2571515T (pt) |
WO (1) | WO2011146109A2 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE036637T2 (hu) | 2011-01-27 | 2018-07-30 | Neuren Pharmaceuticals Ltd | Autizmus spektrumbetegségek kezelése glicil-L-2-metilprolil-L-glutaminsavval |
BR112015012506A2 (pt) * | 2012-11-28 | 2017-07-11 | Neuren Pharmaceuticals Ltd | tratamento de transtornos do espectro do autismo usando ácido glicil-l-2-metilprolil-l-glutâmico |
WO2015013397A2 (en) | 2013-07-25 | 2015-01-29 | Neuren Pharmaceuticals Limited | Neuroprotective bicyclic compounds and methods for their use in treating autism spectrum disorders and neurodevelopmental disorders |
US20180296537A1 (en) * | 2015-06-05 | 2018-10-18 | Novartis Ag | Methods and compositions for diagnosing, treating, and monitoring treatment of shank3 deficiency associated disorders |
WO2021219555A1 (en) * | 2020-04-27 | 2021-11-04 | Universität Ulm | Antisense oligonucleotides for increasing shank3 expression |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070053970A1 (en) * | 2005-05-25 | 2007-03-08 | Guilford F T | Liposomal formulation for oral administration of glutathione (reduced) and/or methylcobalamine for diseases related to glutathione deficiency and deficiency of the methionine remethylation pathway |
EP2012815A4 (en) * | 2006-04-14 | 2009-12-09 | Massachusetts Inst Technology | IDENTIFICATION AND MODULATION OF MOLECULAR PATHWAYS THAT INDUCE THE PLASTICITY OF THE NERVOUS SYSTEM |
GB0703998D0 (en) * | 2007-03-01 | 2007-04-11 | Glaxo Group Ltd | Novel salt |
WO2008153929A1 (en) * | 2007-06-08 | 2008-12-18 | Massachusetts Institute Of Technology | Igf for the treatment of rett syndrome and synaptic disorders |
US8980066B2 (en) * | 2008-03-14 | 2015-03-17 | Applied Materials, Inc. | Thin film metal oxynitride semiconductors |
WO2009143622A1 (en) | 2008-05-29 | 2009-12-03 | Chum | Methods of stratifying, prognosing and diagnosing schizophrenia, mutant nucleic acid molecules and polypeptides |
US20110166029A1 (en) * | 2009-09-08 | 2011-07-07 | David Michael Margulies | Compositions And Methods For Diagnosing Autism Spectrum Disorders |
-
2011
- 2011-05-16 PT PT117838557T patent/PT2571515T/pt unknown
- 2011-05-16 EP EP11783855.7A patent/EP2571515B1/en active Active
- 2011-05-16 WO PCT/US2011/000860 patent/WO2011146109A2/en active Application Filing
- 2011-05-16 ES ES11783855.7T patent/ES2617309T3/es active Active
-
2012
- 2012-03-21 US US13/425,633 patent/US8691762B2/en active Active
-
2014
- 2014-02-28 US US14/192,924 patent/US20140178307A1/en not_active Abandoned
-
2018
- 2018-11-21 US US16/197,434 patent/US20190076553A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2571515A4 (en) | 2013-11-27 |
US20120216302A1 (en) | 2012-08-23 |
US20190076553A1 (en) | 2019-03-14 |
EP2571515A2 (en) | 2013-03-27 |
US8691762B2 (en) | 2014-04-08 |
ES2617309T3 (es) | 2017-06-16 |
EP2571515B1 (en) | 2016-11-30 |
WO2011146109A3 (en) | 2012-04-05 |
WO2011146109A2 (en) | 2011-11-24 |
US20140178307A1 (en) | 2014-06-26 |
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