CA2682390A1 - Pdgfr.beta.-specific inhibitors - Google Patents
Pdgfr.beta.-specific inhibitors Download PDFInfo
- Publication number
- CA2682390A1 CA2682390A1 CA002682390A CA2682390A CA2682390A1 CA 2682390 A1 CA2682390 A1 CA 2682390A1 CA 002682390 A CA002682390 A CA 002682390A CA 2682390 A CA2682390 A CA 2682390A CA 2682390 A1 CA2682390 A1 CA 2682390A1
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- antibody
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- pdgfr
- beta
- antibodies
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Classifications
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- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07—ORGANIC CHEMISTRY
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US92397907P | 2007-04-17 | 2007-04-17 | |
| US60/923,979 | 2007-04-17 | ||
| PCT/US2008/005137 WO2008130704A2 (en) | 2007-04-17 | 2008-04-17 | PDGFRβ-SPECIFIC INHIBITORS |
Publications (1)
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| CA2682390A1 true CA2682390A1 (en) | 2008-10-30 |
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| CA002682390A Abandoned CA2682390A1 (en) | 2007-04-17 | 2008-04-17 | Pdgfr.beta.-specific inhibitors |
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| US20120231537A1 (en) * | 2008-04-30 | 2012-09-13 | Gradalis, Inc. | Highly Pure Plasmid DNA Preparations |
| US20110020924A1 (en) * | 2008-04-30 | 2011-01-27 | Gradalis, Inc. | Highly pure plasmid dna preparations |
| US20110305672A1 (en) | 2008-07-25 | 2011-12-15 | University Of Georgia Research Foundation, Inc. | COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME |
| EP2379718B2 (en) | 2008-12-16 | 2020-12-30 | Novartis AG | Yeast display systems |
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| CA2775400A1 (en) * | 2009-09-28 | 2011-03-31 | Medizinische Universitat Wien | New use of pdgfrbeta inhibitors |
| US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
| EP2686349B1 (en) * | 2011-03-15 | 2020-12-09 | X-Body, Inc. | Antibody screening methods |
| CN102250249A (zh) * | 2011-06-18 | 2011-11-23 | 常州亚当生物技术有限公司 | 一种抗VEGF/PDGFRbeta双特异性抗体及其应用 |
| HK1199883A1 (en) | 2011-08-26 | 2015-07-24 | Merrimack Pharmaceuticals, Inc. | Tandem fc bispecific antibodies |
| EP3712173B1 (en) * | 2011-12-05 | 2023-07-12 | X-Body, Inc. | Pdgf receptor beta binding polypeptides |
| TWI613215B (zh) | 2012-02-22 | 2018-02-01 | 再生元醫藥公司 | 抗－大－內皮素－１（ｂｉｇ－ｅｔ－１）抗體及其用途 |
| JO3405B1 (ar) * | 2013-01-09 | 2019-10-20 | Regeneron Pharma | الأجسام المضادة لمضاد مستقبل عامل النمو المشتق من الصفائح الدموية - بيتا واستخداماتها |
| KR20150143458A (ko) | 2013-03-06 | 2015-12-23 | 메리맥 파마슈티컬즈, 인크. | 항-C-MET 탠덤 Fc 이중특이적 항체 |
| WO2015035342A2 (en) | 2013-09-08 | 2015-03-12 | Oligasis Llc | Factor viii zwitterionic polymer conjugates |
| US9914769B2 (en) | 2014-07-15 | 2018-03-13 | Kymab Limited | Precision medicine for cholesterol treatment |
| DE202014010499U1 (de) | 2013-12-17 | 2015-10-20 | Kymab Limited | Targeting von humaner PCSK9 zur Cholesterinbehandlung |
| KR102127408B1 (ko) * | 2014-01-29 | 2020-06-29 | 삼성전자주식회사 | 항 Her3 scFv 단편 및 이를 포함하는 항 c-Met/항 Her3 이중 특이 항체 |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016061562A2 (en) | 2014-10-17 | 2016-04-21 | Kodiak Sciences Inc. | Butyrylcholinesterase zwitterionic polymer conjugates |
| CA2980385A1 (en) | 2015-03-20 | 2016-09-29 | Johann Wolfgang Goethe-Universitat Frankfurt Am Main | Pericyte long non-coding rnas |
| WO2017106609A2 (en) * | 2015-12-16 | 2017-06-22 | Kadmon Corporation, Llc. | Pdgfr beta antibody |
| CN114404371A (zh) | 2015-12-16 | 2022-04-29 | 瑞泽恩制药公司 | 制造蛋白质微粒的组合物和方法 |
| JP7088454B2 (ja) | 2015-12-30 | 2022-06-21 | コディアック サイエンシーズ インコーポレイテッド | 抗体および抗体複合体 |
| CN116903741A (zh) | 2016-06-20 | 2023-10-20 | 科马布有限公司 | 特异性结合于pd-l1的抗体或其抗原结合片段及其用途 |
| KR102543323B1 (ko) | 2016-10-30 | 2023-06-14 | 상하이 헨리우스 바이오테크, 인크. | 항-pd-l1 항체 및 변이체 |
| WO2018083248A1 (en) | 2016-11-03 | 2018-05-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
| US11440951B2 (en) | 2017-03-13 | 2022-09-13 | The Government Of The United States, As Represented By The Secretary Of The Army | Therapeutic antibodies to Marburg virus |
| CN109021104B (zh) * | 2017-06-12 | 2022-08-12 | 上海睿智化学研究有限公司 | 一种抗人血小板衍生生长因子β受体的抗体及其应用 |
| EP3758751A4 (en) | 2018-02-28 | 2021-11-17 | Wuxi Biologics Ireland Limited. | MONOCLONAL ANTIBODIES AGAINST HUMAN LAG-3, METHOD OF MANUFACTURING AND USING THEREOF |
| CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
| DE102018204828A1 (de) | 2018-03-29 | 2019-10-02 | Ford Global Technologies, Llc | Verhinderung von Glatteis durch Abwasser von Kraftfahrzeugen |
| WO2020029860A1 (zh) | 2018-08-09 | 2020-02-13 | 北京智仁美博生物科技有限公司 | 针对狂犬病病毒的双特异性抗体及其用途 |
| BR112021006352A2 (pt) * | 2018-10-05 | 2021-07-06 | Univ Ewha Ind Collaboration | anticorpo receptor de pdgf e uso do mesmo |
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| CA3170712A1 (en) * | 2020-02-07 | 2021-08-12 | Biorion Technologies B.V. | Platelet derived growth factor receptor (pdgfr) antibodies, conjugates, compositions, and uses thereof. |
| AU2024305352A1 (en) | 2023-06-12 | 2025-12-04 | Amgen Inc. | Lymphotoxin beta receptor agonist binding proteins |
| CN118440214B (zh) * | 2024-04-02 | 2025-01-28 | 山东大学 | 一种靶向PDGFRβ的嵌合抗原受体、CAR-T细胞及应用 |
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| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2147729T3 (es) | 1991-01-31 | 2000-10-01 | Cor Therapeutics Inc | Dominios de la region extracelular de polipeptidos receptores de factor de crecimiento derivado de plaquetas humano. |
| US20020009443A1 (en) * | 1991-12-02 | 2002-01-24 | Vanitha Ramakrishman | Inhibitory immunoglobulin polypeptides to human pdgf beta receptor |
| DE69233745D1 (de) | 1991-12-02 | 2008-10-23 | Cambridge Antibody Tech | Herstellung von Autoantikörpern auf Phagenoberflächen ausgehend von Antikörpersegmentbibliotheken |
| US5817310A (en) * | 1991-12-02 | 1998-10-06 | Cor Therapeutics, Inc. | Inhibitory immunoglobulin polypeptides to human PDGF beta receptor |
| US5620687A (en) | 1993-02-25 | 1997-04-15 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF beta receptors |
| US5976534A (en) | 1993-02-25 | 1999-11-02 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF receptors and heparin |
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| US6811779B2 (en) * | 1994-02-10 | 2004-11-02 | Imclone Systems Incorporated | Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy |
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-
2008
- 2008-04-17 MX MX2009011226A patent/MX2009011226A/es active IP Right Grant
- 2008-04-17 US US12/148,482 patent/US7740850B2/en not_active Expired - Fee Related
- 2008-04-17 AU AU2008242444A patent/AU2008242444B2/en not_active Ceased
- 2008-04-17 JP JP2010504124A patent/JP5209702B2/ja not_active Expired - Fee Related
- 2008-04-17 EA EA200970953A patent/EA019595B1/ru not_active IP Right Cessation
- 2008-04-17 CN CN200880012257A patent/CN101707882A/zh active Pending
- 2008-04-17 WO PCT/US2008/005137 patent/WO2008130704A2/en not_active Ceased
- 2008-04-17 NZ NZ579734A patent/NZ579734A/en not_active IP Right Cessation
- 2008-04-17 UA UAA200910244A patent/UA99608C2/ru unknown
- 2008-04-17 KR KR1020097021652A patent/KR101136262B1/ko not_active Expired - Fee Related
- 2008-04-17 EP EP08743156A patent/EP2139921A2/en not_active Withdrawn
- 2008-04-17 CA CA002682390A patent/CA2682390A1/en not_active Abandoned
- 2008-04-17 BR BRPI0810374-7A2A patent/BRPI0810374A2/pt not_active IP Right Cessation
- 2008-06-25 US US12/674,350 patent/US20110207005A1/en not_active Abandoned
-
2009
- 2009-09-07 IL IL200779A patent/IL200779A0/en unknown
-
2010
- 2010-04-21 US US12/764,121 patent/US20100221267A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ579734A (en) | 2012-01-12 |
| US7740850B2 (en) | 2010-06-22 |
| JP2010524466A (ja) | 2010-07-22 |
| UA99608C2 (en) | 2012-09-10 |
| KR101136262B1 (ko) | 2012-07-05 |
| WO2008130704A2 (en) | 2008-10-30 |
| WO2008130704A3 (en) | 2008-12-24 |
| US20090053241A1 (en) | 2009-02-26 |
| AU2008242444A1 (en) | 2008-10-30 |
| EP2139921A2 (en) | 2010-01-06 |
| US20110207005A1 (en) | 2011-08-25 |
| BRPI0810374A2 (pt) | 2014-10-29 |
| EA200970953A1 (ru) | 2010-10-29 |
| EA019595B1 (ru) | 2014-04-30 |
| JP5209702B2 (ja) | 2013-06-12 |
| MX2009011226A (es) | 2010-04-01 |
| IL200779A0 (en) | 2010-05-17 |
| KR20090130382A (ko) | 2009-12-23 |
| AU2008242444B2 (en) | 2013-05-02 |
| US20100221267A1 (en) | 2010-09-02 |
| CN101707882A (zh) | 2010-05-12 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20160208 |