CA2665080C - Regulatable fusion promoters - Google Patents
Regulatable fusion promoters Download PDFInfo
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- CA2665080C CA2665080C CA2665080A CA2665080A CA2665080C CA 2665080 C CA2665080 C CA 2665080C CA 2665080 A CA2665080 A CA 2665080A CA 2665080 A CA2665080 A CA 2665080A CA 2665080 C CA2665080 C CA 2665080C
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| WO2006132606A1 (en) * | 2005-06-09 | 2006-12-14 | Agency For Science, Technology And Research | Hepatic stellate cell specific promoter and uses thereof |
| DK2341943T3 (en) * | 2008-09-22 | 2019-02-25 | Dicerna Pharmaceuticals Inc | COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS |
| US8829173B2 (en) | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| CN102227503B (zh) * | 2008-09-26 | 2015-10-21 | 托卡根公司 | 重组载体 |
| KR101728655B1 (ko) * | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| ES2786051T3 (es) | 2012-10-25 | 2020-10-08 | Tocagen Inc | Vector retroviral con casete de mini-promotor |
| JP2018526007A (ja) | 2015-09-04 | 2018-09-13 | トカジェン インコーポレーテッド | ２ａペプチドを含む組換えベクター |
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| US4522811A (en) * | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
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| FR2738842B1 (fr) * | 1995-09-15 | 1997-10-31 | Rhone Poulenc Rorer Sa | Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique |
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| DE19831420A1 (de) * | 1998-07-14 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | Expressionssysteme enthaltend chimäre Promotoren mit Bindungsstellen für rekombinante Transkriptionsfaktoren |
| WO2000055378A1 (en) * | 1999-03-16 | 2000-09-21 | Dana-Farber Cancer Institute, Inc. | Lentiviral vector system for high quantity screening |
| WO2000072886A1 (en) | 1999-05-26 | 2000-12-07 | Dana-Farber Cancer Institute, Inc. | Episomally replicating lentiviral vectors |
| JP3704037B2 (ja) * | 1999-11-05 | 2005-10-05 | 独立行政法人産業技術総合研究所 | スライディング可能な機能性キメラ分子 |
| US6579522B1 (en) * | 2000-06-27 | 2003-06-17 | Genvec, Inc. | Replication deficient adenoviral TNF vector |
| JP3613576B2 (ja) * | 2000-10-30 | 2005-01-26 | 独立行政法人産業技術総合研究所 | 細胞内で高機能な核酸分子の選択方法 |
| JP2005504520A (ja) * | 2001-06-13 | 2005-02-17 | イースタン ヴァージニア メディカル スクール | 治療用核酸の標的化発現の方法 |
| JP4745563B2 (ja) * | 2001-09-11 | 2011-08-10 | 一般財団法人 化学物質評価研究機構 | レポータープラスミド |
| GB0130955D0 (en) * | 2001-12-24 | 2002-02-13 | Cancer Res Ventures | Expression system |
| US6863884B2 (en) | 2002-05-01 | 2005-03-08 | Cell Genesys, Inc. | Pseudotyped retroviral vectors |
| US20050196862A1 (en) * | 2002-08-30 | 2005-09-08 | Wooddell Christine I. | DNA cassette for cellular expression of small RNA |
| US6799657B2 (en) * | 2002-10-02 | 2004-10-05 | Carrier Corporation | Absorptive/reactive muffler for variable speed compressors |
| AU2003297474A1 (en) * | 2002-12-18 | 2004-07-14 | Salk Institute For Biological Studies | Methods of inhibiting gene expression by rna interference |
| EP2314687B1 (en) * | 2003-01-17 | 2017-12-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inducible small interfering rna (sirna) expression constructs for targeted gene silencing |
| US20050013018A1 (en) | 2003-07-16 | 2005-01-20 | Alex Ning | Compact lens assembly |
| WO2005007875A2 (en) * | 2003-07-18 | 2005-01-27 | University Of Massachusetts | Enhanced promoters for synthesis of small hairpin rna |
| WO2005007877A2 (en) * | 2003-07-18 | 2005-01-27 | University Of Massachusetts | Regulatable promoters for synthesis of small hairpin rna |
| WO2005021733A2 (en) * | 2003-09-02 | 2005-03-10 | The Scripps Research Institute | Methods and compositions for sirna expression |
| US20050166272A1 (en) * | 2003-12-09 | 2005-07-28 | National Institute Of Advanced Industrial Science And Technology | Enhancement of RNAi activity through mutation |
| JP4753130B2 (ja) * | 2003-12-12 | 2011-08-24 | 独立行政法人産業技術総合研究所 | インターフェロン応答が軽減された長い干渉用二重鎖ｒｎａ |
| JPWO2005068630A1 (ja) * | 2003-12-16 | 2007-07-26 | 独立行政法人産業技術総合研究所 | 干渉用二重鎖ｒｎａ |
| US20050164210A1 (en) * | 2004-01-23 | 2005-07-28 | Vivek Mittal | Regulated polymerase III expression systems and related methods |
| US20050203047A1 (en) * | 2004-03-10 | 2005-09-15 | Ulrich Thomann | Delivery vectors for short interfering RNA, micro-RNA and antisense RNA |
| WO2005112620A2 (en) * | 2004-05-18 | 2005-12-01 | Massachusetts Institute Of Technology | A cre-lox based method for conditional rna interference |
| US8008468B2 (en) * | 2005-02-16 | 2011-08-30 | Benitec, Inc. | RNAi expression constructs with liver-specific enhancer/promoter |
-
2006
- 2006-09-29 AU AU2006297112A patent/AU2006297112B2/en not_active Ceased
- 2006-09-29 WO PCT/US2006/038154 patent/WO2007041350A2/en not_active Ceased
- 2006-09-29 EP EP11160708.1A patent/EP2386564B1/en not_active Not-in-force
- 2006-09-29 EP EP06815854A patent/EP1943265B1/en not_active Not-in-force
- 2006-09-29 US US12/088,921 patent/US20090053295A1/en not_active Abandoned
- 2006-09-29 JP JP2008533689A patent/JP5976986B2/ja not_active Expired - Fee Related
- 2006-09-29 CA CA2665080A patent/CA2665080C/en not_active Expired - Fee Related
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2012
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2015
- 2015-09-04 JP JP2015175115A patent/JP6199934B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP6199934B2 (ja) | 2017-09-20 |
| JP2009509544A (ja) | 2009-03-12 |
| EP1943265A2 (en) | 2008-07-16 |
| AU2006297112B2 (en) | 2013-04-18 |
| CA2665080A1 (en) | 2007-04-12 |
| US20090053295A1 (en) | 2009-02-26 |
| EP1943265B1 (en) | 2012-09-12 |
| EP1943265A4 (en) | 2009-01-14 |
| HK1121165A1 (en) | 2009-04-17 |
| JP2012254098A (ja) | 2012-12-27 |
| WO2007041350A3 (en) | 2007-10-04 |
| WO2007041350A2 (en) | 2007-04-12 |
| AU2006297112A1 (en) | 2007-04-12 |
| JP5976986B2 (ja) | 2016-08-24 |
| EP2386564B1 (en) | 2014-07-16 |
| JP2016000047A (ja) | 2016-01-07 |
| EP2386564A1 (en) | 2011-11-16 |
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