CA2631498A1 - Hcv prodrug formulation - Google Patents
Hcv prodrug formulation Download PDFInfo
- Publication number
- CA2631498A1 CA2631498A1 CA002631498A CA2631498A CA2631498A1 CA 2631498 A1 CA2631498 A1 CA 2631498A1 CA 002631498 A CA002631498 A CA 002631498A CA 2631498 A CA2631498 A CA 2631498A CA 2631498 A1 CA2631498 A1 CA 2631498A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- composition according
- solid suspension
- poloxomer
- compressed tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Landscapes
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- Medicinal Preparation (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US75014605P | 2005-12-14 | 2005-12-14 | |
| US60/750,146 | 2005-12-14 | ||
| US83059406P | 2006-07-12 | 2006-07-12 | |
| US60/830,594 | 2006-07-12 | ||
| PCT/EP2006/069262 WO2007068615A2 (en) | 2005-12-14 | 2006-12-04 | Hcv prodrug formulation |
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| CA2631498A1 true CA2631498A1 (en) | 2007-06-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002631498A Abandoned CA2631498A1 (en) | 2005-12-14 | 2006-12-04 | Hcv prodrug formulation |
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| US (1) | US7795237B2 (pt) |
| EP (1) | EP1962808B1 (pt) |
| JP (1) | JP5649783B2 (pt) |
| KR (1) | KR20080089344A (pt) |
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| AT (1) | ATE482690T1 (pt) |
| AU (1) | AU2006326130B2 (pt) |
| BR (1) | BRPI0619890A2 (pt) |
| CA (1) | CA2631498A1 (pt) |
| CR (1) | CR10026A (pt) |
| DE (1) | DE602006017257D1 (pt) |
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| EC (1) | ECSP088528A (pt) |
| IL (1) | IL191791A (pt) |
| MA (1) | MA30056B1 (pt) |
| NO (1) | NO20082563L (pt) |
| PL (1) | PL1962808T3 (pt) |
| PT (1) | PT1962808E (pt) |
| RU (1) | RU2435592C2 (pt) |
| TW (1) | TWI382840B (pt) |
| WO (1) | WO2007068615A2 (pt) |
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| EP1713514B1 (en) * | 2004-01-28 | 2021-11-24 | Johns Hopkins University | Drugs and gene carrier particles that rapidly move through mucous barriers |
| BRPI0714963A2 (pt) * | 2006-08-16 | 2013-07-30 | Novartis Ag | processo de fabricaÇço de dispersÕes sàlidas de compostos terapÊuticos altamente cristalinos |
| AU2007292902B8 (en) * | 2006-09-08 | 2013-09-05 | Johns Hopkins University | Compositions and methods for enhancing transport through mucus |
| WO2008119659A2 (en) | 2007-03-29 | 2008-10-09 | F. Hoffmann-La Roche Ag | Pharmaceutical composition and process |
| AU2010206224B2 (en) * | 2009-01-21 | 2012-12-13 | F. Hoffmann-La Roche Ag | Pharmaceutical compositions comprising a HCV polymerase inhibitor prodrug |
| AR075180A1 (es) * | 2009-01-29 | 2011-03-16 | Novartis Ag | Formulaciones orales solidas de una pirido-pirimidinona |
| GB0909680D0 (en) | 2009-06-05 | 2009-07-22 | Euro Celtique Sa | Dosage form |
| CN102725303B (zh) | 2010-01-28 | 2015-05-27 | 里博科学有限责任公司 | 作为抗hcv化合物的4’-叠氮基-核苷 |
| CA2798884C (en) | 2010-05-10 | 2016-09-13 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
| WO2011141490A1 (en) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Combination of active loaded granules with additional actives |
| SG184523A1 (en) | 2010-05-10 | 2012-11-29 | Euro Celtique Sa | Pharmaceutical compositions comprising hydromorphone and naloxone |
| CA2816977C (en) * | 2010-11-05 | 2019-10-29 | The Johns Hopkins University | Compositions and methods relating to reduced mucoadhesion |
| EP2455068A1 (en) * | 2010-11-09 | 2012-05-23 | F. Hoffmann-La Roche AG | Pharmaceutical composition for treating HCV infections |
| TW201300106A (zh) * | 2010-11-09 | 2013-01-01 | Hoffmann La Roche | 治療ｈｃｖ感染之醫藥組合物 |
| JP5917964B2 (ja) * | 2012-03-19 | 2016-05-18 | 富士ゼロックス株式会社 | 錠剤、錠剤の製造方法、錠剤管理装置、錠剤照合装置及びプログラム |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| KR102140989B1 (ko) * | 2012-05-03 | 2020-08-04 | 칼라 파마슈티컬스, 인크. | 개선된 점막 수송을 나타내는 제약 나노입자 |
| WO2013166408A1 (en) | 2012-05-03 | 2013-11-07 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| AU2014216178B2 (en) | 2013-02-15 | 2018-06-28 | KALA BIO, Inc. | Therapeutic compounds and uses thereof |
| EP3763710A1 (en) | 2013-02-20 | 2021-01-13 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| NZ719185A (en) | 2013-11-01 | 2017-11-24 | Kala Pharmaceuticals Inc | Crystalline forms of therapeutic compounds and uses thereof |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| JP6232135B2 (ja) | 2013-11-13 | 2017-11-15 | ユーロ−セルティーク エス．エイ． | 疼痛およびオピオイドによる腸機能障害症候群の治療のためのヒドロモルホンおよびナロキソン |
| CA3036065A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CA3036340A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509422A4 (en) | 2016-09-08 | 2020-05-20 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| EP3381479A1 (de) * | 2017-03-29 | 2018-10-03 | ARTOSS GmbH | Trägerzusammensetzung für knochenersatzmaterialien |
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| ATE427124T1 (de) | 1996-06-26 | 2009-04-15 | Univ Texas | Heiss-geschmolzene extrudierbare pharmazeutische formulierung |
| JP2001520984A (ja) * | 1997-10-27 | 2001-11-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 水難溶性薬剤の固態溶剤及び固体分散体 |
| HU229938B1 (en) * | 2001-05-03 | 2015-01-28 | Hoffmann La Roche | Pharmaceutical dosage form of amorphous nelfinavir mesylate |
| DE10208344A1 (de) | 2002-02-27 | 2003-09-04 | Roehm Gmbh | Schmelzextrusion von Wirkstoffsalzen |
| TWI332507B (en) * | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
| US20050044529A1 (en) | 2003-08-20 | 2005-02-24 | Microsoft Corporation | Task library of task data for a plurality of components on a computer system |
| US20050048112A1 (en) | 2003-08-28 | 2005-03-03 | Jorg Breitenbach | Solid pharmaceutical dosage form |
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2006
- 2006-12-04 AU AU2006326130A patent/AU2006326130B2/en not_active Ceased
- 2006-12-04 KR KR1020087014073A patent/KR20080089344A/ko not_active Application Discontinuation
- 2006-12-04 AT AT06830328T patent/ATE482690T1/de active
- 2006-12-04 BR BRPI0619890-2A patent/BRPI0619890A2/pt not_active IP Right Cessation
- 2006-12-04 PT PT06830328T patent/PT1962808E/pt unknown
- 2006-12-04 DE DE602006017257T patent/DE602006017257D1/de active Active
- 2006-12-04 RU RU2008128361/15A patent/RU2435592C2/ru not_active IP Right Cessation
- 2006-12-04 DK DK06830328.8T patent/DK1962808T3/da active
- 2006-12-04 EP EP06830328A patent/EP1962808B1/en active Active
- 2006-12-04 PL PL06830328T patent/PL1962808T3/pl unknown
- 2006-12-04 CA CA002631498A patent/CA2631498A1/en not_active Abandoned
- 2006-12-04 JP JP2008544952A patent/JP5649783B2/ja not_active Expired - Fee Related
- 2006-12-04 WO PCT/EP2006/069262 patent/WO2007068615A2/en active Application Filing
- 2006-12-12 TW TW095146501A patent/TWI382840B/zh not_active IP Right Cessation
- 2006-12-12 AR ARP060105459A patent/AR058313A1/es not_active Application Discontinuation
- 2006-12-13 US US11/637,999 patent/US7795237B2/en not_active Expired - Fee Related
-
2008
- 2008-05-28 CR CR10026A patent/CR10026A/es not_active Application Discontinuation
- 2008-05-28 IL IL191791A patent/IL191791A/en not_active IP Right Cessation
- 2008-06-02 NO NO20082563A patent/NO20082563L/no not_active Application Discontinuation
- 2008-06-12 EC EC2008008528A patent/ECSP088528A/es unknown
- 2008-06-16 MA MA31038A patent/MA30056B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0619890A2 (pt) | 2011-10-25 |
| RU2008128361A (ru) | 2010-01-20 |
| ATE482690T1 (de) | 2010-10-15 |
| ECSP088528A (es) | 2008-07-30 |
| IL191791A0 (en) | 2008-12-29 |
| NO20082563L (no) | 2008-07-03 |
| TW200803873A (en) | 2008-01-16 |
| AR058313A1 (es) | 2008-01-30 |
| US20070202175A1 (en) | 2007-08-30 |
| IL191791A (en) | 2011-06-30 |
| AU2006326130B2 (en) | 2011-09-22 |
| EP1962808A2 (en) | 2008-09-03 |
| RU2435592C2 (ru) | 2011-12-10 |
| TWI382840B (zh) | 2013-01-21 |
| DK1962808T3 (da) | 2010-11-08 |
| JP2009519289A (ja) | 2009-05-14 |
| PT1962808E (pt) | 2010-10-29 |
| WO2007068615A3 (en) | 2007-09-07 |
| WO2007068615A2 (en) | 2007-06-21 |
| PL1962808T3 (pl) | 2011-03-31 |
| MA30056B1 (fr) | 2008-12-01 |
| EP1962808B1 (en) | 2010-09-29 |
| AU2006326130A1 (en) | 2007-06-21 |
| US7795237B2 (en) | 2010-09-14 |
| DE602006017257D1 (de) | 2010-11-11 |
| KR20080089344A (ko) | 2008-10-06 |
| CR10026A (es) | 2008-07-29 |
| JP5649783B2 (ja) | 2015-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20141028 |