CA2630413C - Procede de recuperation d'iopromide, a partir de solution-mere, convenant a des fins pharmaceutiques - Google Patents

Procede de recuperation d'iopromide, a partir de solution-mere, convenant a des fins pharmaceutiques Download PDF

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Publication number
CA2630413C
CA2630413C CA2630413A CA2630413A CA2630413C CA 2630413 C CA2630413 C CA 2630413C CA 2630413 A CA2630413 A CA 2630413A CA 2630413 A CA2630413 A CA 2630413A CA 2630413 C CA2630413 C CA 2630413C
Authority
CA
Canada
Prior art keywords
iopromide
isomer
crystallizate
dissolved
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2630413A
Other languages
English (en)
Other versions
CA2630413A1 (fr
Inventor
Hartmut Kagerer
Meike Dembeck
Hartmut Seba
Ingo Ortmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200510059191 external-priority patent/DE102005059191B4/de
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of CA2630413A1 publication Critical patent/CA2630413A1/fr
Application granted granted Critical
Publication of CA2630413C publication Critical patent/CA2630413C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2630413A 2005-12-05 2006-11-10 Procede de recuperation d'iopromide, a partir de solution-mere, convenant a des fins pharmaceutiques Expired - Fee Related CA2630413C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE200510059191 DE102005059191B4 (de) 2005-12-05 2005-12-05 Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen
DE102005059191.4 2005-12-05
US74817505P 2005-12-08 2005-12-08
US60/748,175 2005-12-08
PCT/EP2006/010943 WO2007065534A1 (fr) 2005-12-05 2006-11-10 Procede de recuperation d'iopromide a usage pharmaceutique a partir d'eaux meres

Publications (2)

Publication Number Publication Date
CA2630413A1 CA2630413A1 (fr) 2007-06-14
CA2630413C true CA2630413C (fr) 2013-06-25

Family

ID=37773154

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2630413A Expired - Fee Related CA2630413C (fr) 2005-12-05 2006-11-10 Procede de recuperation d'iopromide, a partir de solution-mere, convenant a des fins pharmaceutiques

Country Status (5)

Country Link
EP (1) EP1960348A1 (fr)
JP (1) JP2009518325A (fr)
KR (1) KR20080073369A (fr)
CA (1) CA2630413C (fr)
WO (1) WO2007065534A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100976097B1 (ko) * 2008-12-05 2010-08-16 주식회사 대웅제약 이오프로마이드의 ｚ 이성체를 선택적으로 결정화하는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
GB9720969D0 (en) * 1997-10-02 1997-12-03 Nycomed Imaging As Process

Also Published As

Publication number Publication date
JP2009518325A (ja) 2009-05-07
EP1960348A1 (fr) 2008-08-27
KR20080073369A (ko) 2008-08-08
WO2007065534A1 (fr) 2007-06-14
CA2630413A1 (fr) 2007-06-14

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Effective date: 20141110