CA2616517A1 - Abl kinase inhibition - Google Patents
Abl kinase inhibition Download PDFInfo
- Publication number
- CA2616517A1 CA2616517A1 CA002616517A CA2616517A CA2616517A1 CA 2616517 A1 CA2616517 A1 CA 2616517A1 CA 002616517 A CA002616517 A CA 002616517A CA 2616517 A CA2616517 A CA 2616517A CA 2616517 A1 CA2616517 A1 CA 2616517A1
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- Prior art keywords
- compound
- abl
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- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70277105P | 2005-07-26 | 2005-07-26 | |
| US60/702,771 | 2005-07-26 | ||
| US78516106P | 2006-03-23 | 2006-03-23 | |
| US60/785,161 | 2006-03-23 | ||
| US83025706P | 2006-07-12 | 2006-07-12 | |
| US60/830,257 | 2006-07-12 | ||
| PCT/US2006/028984 WO2007014250A2 (en) | 2005-07-26 | 2006-07-26 | Abl kinase inhibition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2616517A1 true CA2616517A1 (en) | 2007-02-01 |
Family
ID=37683933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002616517A Abandoned CA2616517A1 (en) | 2005-07-26 | 2006-07-26 | Abl kinase inhibition |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090298844A1 (enExample) |
| EP (1) | EP1906967A4 (enExample) |
| JP (2) | JP2009502937A (enExample) |
| AU (1) | AU2006272609A1 (enExample) |
| CA (1) | CA2616517A1 (enExample) |
| WO (1) | WO2007014250A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE529536T1 (de) * | 2005-12-01 | 2011-11-15 | Bristol Myers Squibb Co | Verfahren zur identifizierung und behandlung von komplexe karyotypen zeigenden individuen |
| JP2009544705A (ja) * | 2006-07-26 | 2009-12-17 | メルク エンド カムパニー インコーポレーテッド | がんの治療のために有用なｍｋ−０４５７の新規乳酸製剤 |
| IN2014KN02601A (enExample) | 2012-04-24 | 2015-05-08 | Vertex Pharma | |
| SMT201900107T1 (it) | 2013-03-12 | 2019-02-28 | Vertex Pharma | Inibitori della dna-pk |
| TWI647220B (zh) | 2013-03-15 | 2019-01-11 | 美商西建卡爾有限責任公司 | 雜芳基化合物及其用途 |
| UA120248C2 (uk) | 2013-03-15 | 2019-11-11 | Селджен Кар Ллс | Гетероарильні сполуки та їх застосування |
| US9663524B2 (en) | 2013-03-15 | 2017-05-30 | Celgene Car Llc | Substituted pyrido[2,3-d]pyrimidines as protein kinase inhibitors |
| PL3424920T3 (pl) | 2013-10-17 | 2020-11-16 | Vertex Pharmaceuticals Incorporated | Kokryształy (S)-N-metylo-8-(1-((2'-metylo-4’,6'-dideutero-[4,5'-bipirymidyn]-6-ylo)amino)propan-2-ylo)chinolino-4-karboksyamidu i ich deuterowane pochodne jako inhibitory DNA-PK |
| MX394860B (es) | 2016-09-27 | 2025-03-24 | Vertex Pharma | Metodo para tratar cancer usando una combinacion de agentes que dañan adn e inhibidores de proteina cinasa dependiente de adn (adn-pk). |
Family Cites Families (3)
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|---|---|---|---|---|
| EP2017335B1 (en) * | 2001-10-05 | 2010-12-01 | Novartis AG | Mutated Abl kinase domains |
| MY141867A (en) * | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| AU2005272815A1 (en) * | 2004-08-13 | 2006-02-23 | Genentech, Inc. | Thiazole based inhibitors of ATP-utilizing enzymes |
-
2006
- 2006-07-26 US US11/989,300 patent/US20090298844A1/en not_active Abandoned
- 2006-07-26 JP JP2008524094A patent/JP2009502937A/ja active Pending
- 2006-07-26 EP EP06800350A patent/EP1906967A4/en not_active Withdrawn
- 2006-07-26 WO PCT/US2006/028984 patent/WO2007014250A2/en not_active Ceased
- 2006-07-26 CA CA002616517A patent/CA2616517A1/en not_active Abandoned
- 2006-07-26 AU AU2006272609A patent/AU2006272609A1/en not_active Abandoned
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2012
- 2012-05-29 JP JP2012122081A patent/JP2012158616A/ja active Pending
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| Publication number | Publication date |
|---|---|
| WO2007014250A3 (en) | 2007-06-28 |
| JP2009502937A (ja) | 2009-01-29 |
| US20090298844A1 (en) | 2009-12-03 |
| WO2007014250A8 (en) | 2008-02-21 |
| JP2012158616A (ja) | 2012-08-23 |
| EP1906967A4 (en) | 2010-07-28 |
| WO2007014250A2 (en) | 2007-02-01 |
| AU2006272609A1 (en) | 2007-02-01 |
| EP1906967A2 (en) | 2008-04-09 |
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