CA2586973A1 - Amino-alcools tricycliques, processus de synthese et utilisation comme anti-inflammatoires - Google Patents
Amino-alcools tricycliques, processus de synthese et utilisation comme anti-inflammatoires Download PDFInfo
- Publication number
- CA2586973A1 CA2586973A1 CA002586973A CA2586973A CA2586973A1 CA 2586973 A1 CA2586973 A1 CA 2586973A1 CA 002586973 A CA002586973 A CA 002586973A CA 2586973 A CA2586973 A CA 2586973A CA 2586973 A1 CA2586973 A1 CA 2586973A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- groups
- alkyl
- general formula
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004063227.8 | 2004-12-22 | ||
DE102004063227A DE102004063227A1 (de) | 2004-12-22 | 2004-12-22 | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
PCT/EP2005/013943 WO2006066950A2 (fr) | 2004-12-22 | 2005-12-20 | Aminoalcools tricycliques, procedes de realisation associes et utilisation comme anti-inflammatoires |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2586973A1 true CA2586973A1 (fr) | 2006-06-29 |
Family
ID=36250953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002586973A Abandoned CA2586973A1 (fr) | 2004-12-22 | 2005-12-20 | Amino-alcools tricycliques, processus de synthese et utilisation comme anti-inflammatoires |
Country Status (14)
Country | Link |
---|---|
JP (1) | JP2008524300A (fr) |
KR (1) | KR20070089948A (fr) |
CN (1) | CN101087780A (fr) |
AR (1) | AR055016A1 (fr) |
AU (1) | AU2005318354A1 (fr) |
BR (1) | BRPI0519710A2 (fr) |
CA (1) | CA2586973A1 (fr) |
DE (1) | DE102004063227A1 (fr) |
GT (1) | GT200500385A (fr) |
IL (1) | IL183060A0 (fr) |
MX (1) | MX2007007420A (fr) |
PA (1) | PA8657801A1 (fr) |
PE (1) | PE20061197A1 (fr) |
WO (1) | WO2006066950A2 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE502004002403D1 (de) | 2003-10-08 | 2007-02-01 | Schering Ag | Tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US7297700B2 (en) | 2005-03-24 | 2007-11-20 | Renovis, Inc. | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof |
EP1834948A1 (fr) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Derives de tetrahydronaphtalene , procedes pour leur production et leur utilisation en tant qu'anti-inflammatoires |
TWI464148B (zh) | 2006-03-16 | 2014-12-11 | Evotec Us Inc | 作為p2x7調節劑之雙環雜芳基化合物與其用途 |
EP1917963A1 (fr) * | 2006-10-31 | 2008-05-07 | Bayer Schering Pharma Aktiengesellschaft | Imidazoles cycliques substitués par un groupe phényle, procédé pour leur préparation et leur utilisation comme des agents anti-inflammatoires |
EP2072509A1 (fr) | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-aryl-1H-quinoline-2-ones : leur procédé de fabrication et leur utilisation en tant qu'agents anti-inflammatoires |
CA2864085C (fr) | 2012-02-08 | 2021-11-23 | Sunovion Pharmaceuticals Inc. | Composes heteroaryles et procede d'utilisation correspondant |
WO2018023070A1 (fr) | 2016-07-29 | 2018-02-01 | Sunovion Pharmaceuticals, Inc. | Composés et compositions, et utilisations associées |
US10196403B2 (en) | 2016-07-29 | 2019-02-05 | Sunovion Pharmaceuticals Inc. | Compounds and compositions and uses thereof |
MX2020000523A (es) | 2017-08-02 | 2020-08-20 | Sunovion Pharmaceuticals Inc | Compuestos de isocromano y usos de los mismos. |
WO2020186165A1 (fr) | 2019-03-14 | 2020-09-17 | Sunovion Pharmaceuticals Inc. | Sels d'un composé d'isochromanyle et formes cristallines, procédés de préparation, utilisations thérapeutiques et compositions pharmaceutiques associées |
KR102462991B1 (ko) * | 2020-11-02 | 2022-11-04 | 한국해양과학기술원 | 남극-유래 진균 균주 아크레모늄(Acremonium sp.) SF-7394에서 분리한 화합물 및 이를 포함하는 항염증, 항암 또는 항당뇨용 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10038639A1 (de) * | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
ES2298508T3 (es) * | 2002-03-26 | 2008-05-16 | Boehringer Ingelheim Pharmaceuticals Inc. | Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos. |
DE10215316C1 (de) * | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
DE502004002403D1 (de) * | 2003-10-08 | 2007-02-01 | Schering Ag | Tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
GB0418045D0 (en) * | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
DE102004044680B3 (de) * | 2004-09-09 | 2006-06-08 | Schering Ag | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
-
2004
- 2004-12-22 DE DE102004063227A patent/DE102004063227A1/de not_active Withdrawn
-
2005
- 2005-12-20 WO PCT/EP2005/013943 patent/WO2006066950A2/fr not_active Application Discontinuation
- 2005-12-20 JP JP2007547379A patent/JP2008524300A/ja active Pending
- 2005-12-20 CA CA002586973A patent/CA2586973A1/fr not_active Abandoned
- 2005-12-20 MX MX2007007420A patent/MX2007007420A/es not_active Application Discontinuation
- 2005-12-20 KR KR1020077014116A patent/KR20070089948A/ko not_active Application Discontinuation
- 2005-12-20 BR BRPI0519710-4A patent/BRPI0519710A2/pt not_active Application Discontinuation
- 2005-12-20 AU AU2005318354A patent/AU2005318354A1/en not_active Abandoned
- 2005-12-20 CN CNA2005800442843A patent/CN101087780A/zh active Pending
- 2005-12-22 PA PA20058657801A patent/PA8657801A1/es unknown
- 2005-12-22 AR ARP050105486A patent/AR055016A1/es not_active Application Discontinuation
- 2005-12-22 GT GT200500385A patent/GT200500385A/es unknown
-
2006
- 2006-01-03 PE PE2006000009A patent/PE20061197A1/es not_active Application Discontinuation
-
2007
- 2007-05-08 IL IL183060A patent/IL183060A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008524300A (ja) | 2008-07-10 |
PA8657801A1 (es) | 2006-12-07 |
IL183060A0 (en) | 2007-09-20 |
DE102004063227A1 (de) | 2006-07-06 |
WO2006066950A2 (fr) | 2006-06-29 |
BRPI0519710A2 (pt) | 2009-03-10 |
KR20070089948A (ko) | 2007-09-04 |
GT200500385A (es) | 2006-08-03 |
AR055016A1 (es) | 2007-08-01 |
MX2007007420A (es) | 2007-07-17 |
CN101087780A (zh) | 2007-12-12 |
AU2005318354A1 (en) | 2006-06-29 |
WO2006066950A3 (fr) | 2006-08-17 |
PE20061197A1 (es) | 2006-12-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |