CA2575422A1 - Method of detecting mutations in the gene encoding cytochrome p450-2c19 - Google Patents

Method of detecting mutations in the gene encoding cytochrome p450-2c19 Download PDF

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Publication number
CA2575422A1
CA2575422A1 CA002575422A CA2575422A CA2575422A1 CA 2575422 A1 CA2575422 A1 CA 2575422A1 CA 002575422 A CA002575422 A CA 002575422A CA 2575422 A CA2575422 A CA 2575422A CA 2575422 A1 CA2575422 A1 CA 2575422A1
Authority
CA
Canada
Prior art keywords
seq
cyp2c19
primers
nucleotide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002575422A
Other languages
English (en)
French (fr)
Inventor
James D. Gordon
Frank Merante
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Molecular Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2575422A1 publication Critical patent/CA2575422A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002575422A 2004-07-30 2005-07-29 Method of detecting mutations in the gene encoding cytochrome p450-2c19 Abandoned CA2575422A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59212404P 2004-07-30 2004-07-30
US60/592,124 2004-07-30
PCT/CA2005/001180 WO2006010266A1 (en) 2004-07-30 2005-07-29 Method of detecting mutations in the gene encoding cytochrome p450-2c19

Publications (1)

Publication Number Publication Date
CA2575422A1 true CA2575422A1 (en) 2006-02-02

Family

ID=35785879

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002575422A Abandoned CA2575422A1 (en) 2004-07-30 2005-07-29 Method of detecting mutations in the gene encoding cytochrome p450-2c19

Country Status (6)

Country Link
US (1) US20080248466A1 (enExample)
EP (1) EP1778868A4 (enExample)
JP (1) JP2008507955A (enExample)
AU (1) AU2005266805B2 (enExample)
CA (1) CA2575422A1 (enExample)
WO (1) WO2006010266A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781811B1 (en) * 2004-06-30 2010-06-23 Luminex Molecular Diagnostics, Inc. Method of detecting mutations in the gene encoding cytochrome p450-2d6
CA2571817A1 (en) * 2004-06-30 2006-01-12 Tm Bioscience Pgx, Inc. Method of detecting mutations in the gene encoding cytochrome p450-2c9
WO2009128730A1 (en) * 2008-01-25 2009-10-22 Patrick Gladding Methods and compositions for the assessment of drug response
US20120035060A1 (en) * 2010-08-03 2012-02-09 Bioarray Solutions, Ltd. Highly multiplexed genotyping using leukoreduced blood samples

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
JPH0856695A (ja) * 1993-07-20 1996-03-05 Sumitomo Chem Co Ltd 安全性評価方法
CA2128399A1 (en) * 1993-07-20 1995-01-21 Koji Hayashi Method for safety evaluation of chemical compound using recombinant yeast expressing human cytochrome p450
SE517285C2 (sv) * 1998-07-24 2002-05-21 Delaval Holding Ab Anordning för automatisk mjölkning av ett djur
JP2002523111A (ja) * 1998-08-28 2002-07-30 サンテック モレキュラー ダイアグノスティックス エービー 特定医薬を代謝することに対する患者の能力を測定する方法
GB9902971D0 (en) * 1999-02-11 1999-03-31 Zeneca Ltd Assay
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags
GB0021286D0 (en) * 2000-08-30 2000-10-18 Gemini Genomics Ab Identification of drug metabolic capacity
EP2327794A3 (en) * 2001-01-25 2011-09-14 TM Bioscience Corporation Polynucleotides for use as tags and tag complements, manufacture and use thereof
EP1373574A4 (en) * 2001-03-30 2007-01-03 Ge Healthcare Bio Sciences Ab BIOPUCES ANALYSIS OF SIMPLE POLYMORPHISMS NUCL OTIDE
US7195877B2 (en) * 2001-07-20 2007-03-27 Bioventures, Inc. Cytochrome P450 genetic variations
DE10237691B4 (de) * 2002-08-15 2010-01-28 Biotez Berlin-Buch Gmbh Biochemisch-Technologisches Zentrum Verfahren zum Nachweis von Einzelnukleotid-Polymorphismen (SNP) in Genen des Arzneimittelmetabolismus und Testkit zur Durchführung des Verfahrens
CA2571817A1 (en) * 2004-06-30 2006-01-12 Tm Bioscience Pgx, Inc. Method of detecting mutations in the gene encoding cytochrome p450-2c9

Also Published As

Publication number Publication date
WO2006010266A1 (en) 2006-02-02
EP1778868A1 (en) 2007-05-02
US20080248466A1 (en) 2008-10-09
AU2005266805A1 (en) 2006-02-02
AU2005266805B2 (en) 2010-10-28
JP2008507955A (ja) 2008-03-21
EP1778868A4 (en) 2007-12-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued