CA2554125A1 - Method for producing a 2-(ethoxymethyl)tropane derivative - Google Patents
Method for producing a 2-(ethoxymethyl)tropane derivative Download PDFInfo
- Publication number
- CA2554125A1 CA2554125A1 CA002554125A CA2554125A CA2554125A1 CA 2554125 A1 CA2554125 A1 CA 2554125A1 CA 002554125 A CA002554125 A CA 002554125A CA 2554125 A CA2554125 A CA 2554125A CA 2554125 A1 CA2554125 A1 CA 2554125A1
- Authority
- CA
- Canada
- Prior art keywords
- process according
- formula
- transfer catalyst
- ethoxymethyl
- ethyl bromide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004004965A DE102004004965B4 (de) | 2004-01-31 | 2004-01-31 | Verfahren zur Herstellung eines 2-(Ethoxymethyl)-tropanderivates |
| DE102004004965.3 | 2004-01-31 | ||
| PCT/EP2005/000512 WO2005073228A1 (de) | 2004-01-31 | 2005-01-20 | Verfahren zur herstellung eines 2-(ethoxymethyl)-tropanderivates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2554125A1 true CA2554125A1 (en) | 2005-08-11 |
Family
ID=34801391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002554125A Abandoned CA2554125A1 (en) | 2004-01-31 | 2005-01-20 | Method for producing a 2-(ethoxymethyl)tropane derivative |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7544802B2 (https=) |
| EP (1) | EP1713800B1 (https=) |
| JP (1) | JP2007519660A (https=) |
| CN (1) | CN1910180B (https=) |
| AR (1) | AR047515A1 (https=) |
| AT (1) | ATE449095T1 (https=) |
| AU (1) | AU2005209382B2 (https=) |
| CA (1) | CA2554125A1 (https=) |
| DE (2) | DE102004004965B4 (https=) |
| DK (1) | DK1713800T3 (https=) |
| MY (1) | MY141935A (https=) |
| NZ (1) | NZ548092A (https=) |
| PE (1) | PE20050770A1 (https=) |
| TW (1) | TWI338690B (https=) |
| UY (1) | UY28730A1 (https=) |
| WO (1) | WO2005073228A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017324406A1 (en) | 2016-09-07 | 2019-05-02 | Saniona A/S | Tesofensine compositions |
| CN115572289A (zh) * | 2022-10-24 | 2023-01-06 | 龙曦宁（上海）医药科技有限公司 | 一种特索芬辛的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3238414B2 (ja) * | 1996-02-22 | 2001-12-17 | ニューロサーチ・アクティーゼルスカブ | トロパン―誘導体、その製造方法及びその使用方法 |
| EP1397358A1 (en) * | 2001-05-23 | 2004-03-17 | Neurosearch A/S | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| WO2003045388A1 (en) * | 2001-11-30 | 2003-06-05 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| WO2021028011A1 (en) | 2019-08-09 | 2021-02-18 | Quintus Technologies Ab | System and method for handling and isostatic pressure treatment of a load |
-
2004
- 2004-01-31 DE DE102004004965A patent/DE102004004965B4/de not_active Expired - Fee Related
-
2005
- 2005-01-20 DE DE502005008535T patent/DE502005008535D1/de not_active Expired - Lifetime
- 2005-01-20 JP JP2006550028A patent/JP2007519660A/ja active Pending
- 2005-01-20 EP EP05701061A patent/EP1713800B1/de not_active Expired - Lifetime
- 2005-01-20 CN CN2005800027516A patent/CN1910180B/zh not_active Expired - Fee Related
- 2005-01-20 NZ NZ548092A patent/NZ548092A/xx unknown
- 2005-01-20 AT AT05701061T patent/ATE449095T1/de active
- 2005-01-20 WO PCT/EP2005/000512 patent/WO2005073228A1/de not_active Ceased
- 2005-01-20 CA CA002554125A patent/CA2554125A1/en not_active Abandoned
- 2005-01-20 AU AU2005209382A patent/AU2005209382B2/en not_active Expired - Fee Related
- 2005-01-20 DK DK05701061.3T patent/DK1713800T3/da active
- 2005-01-28 TW TW094102759A patent/TWI338690B/zh active
- 2005-01-28 PE PE2005000107A patent/PE20050770A1/es not_active Application Discontinuation
- 2005-01-28 AR ARP050100301A patent/AR047515A1/es unknown
- 2005-01-28 MY MYPI20050353A patent/MY141935A/en unknown
- 2005-01-28 UY UY28730A patent/UY28730A1/es not_active Application Discontinuation
- 2005-01-31 US US11/047,260 patent/US7544802B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1910180B (zh) | 2010-05-12 |
| DE102004004965A1 (de) | 2005-09-01 |
| NZ548092A (en) | 2009-07-31 |
| EP1713800B1 (de) | 2009-11-18 |
| AU2005209382A1 (en) | 2005-08-11 |
| HK1097845A1 (zh) | 2007-07-06 |
| US20050171145A1 (en) | 2005-08-04 |
| CN1910180A (zh) | 2007-02-07 |
| WO2005073228A1 (de) | 2005-08-11 |
| AR047515A1 (es) | 2006-01-25 |
| PE20050770A1 (es) | 2005-11-10 |
| DE102004004965B4 (de) | 2006-01-05 |
| UY28730A1 (es) | 2005-09-30 |
| US7544802B2 (en) | 2009-06-09 |
| TW200538455A (en) | 2005-12-01 |
| EP1713800A2 (de) | 2006-10-25 |
| AU2005209382B2 (en) | 2011-02-17 |
| WO2005073228A8 (de) | 2005-10-27 |
| DE502005008535D1 (de) | 2009-12-31 |
| ATE449095T1 (de) | 2009-12-15 |
| TWI338690B (en) | 2011-03-11 |
| JP2007519660A (ja) | 2007-07-19 |
| DK1713800T3 (da) | 2010-03-29 |
| MY141935A (en) | 2010-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20130121 |