CA2551689A1 - Memantine for the treatment of mild and mild-to-moderate alzheimer's disease - Google Patents
Memantine for the treatment of mild and mild-to-moderate alzheimer's disease Download PDFInfo
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- CA2551689A1 CA2551689A1 CA002551689A CA2551689A CA2551689A1 CA 2551689 A1 CA2551689 A1 CA 2551689A1 CA 002551689 A CA002551689 A CA 002551689A CA 2551689 A CA2551689 A CA 2551689A CA 2551689 A1 CA2551689 A1 CA 2551689A1
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- memantine
- disease
- alzheimer
- mild
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Radiation-Therapy Devices (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53455304P | 2004-01-05 | 2004-01-05 | |
| US60/534,553 | 2004-01-05 | ||
| US54217604P | 2004-02-04 | 2004-02-04 | |
| US60/542,176 | 2004-02-04 | ||
| PCT/US2005/000145 WO2005067908A2 (en) | 2004-01-05 | 2005-01-05 | Memantine for the treatment of mild and mild-to-moderate alzheimer’s disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2551689A1 true CA2551689A1 (en) | 2005-07-28 |
Family
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Family Applications (1)
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|---|---|---|---|
| CA002551689A Abandoned CA2551689A1 (en) | 2004-01-05 | 2005-01-05 | Memantine for the treatment of mild and mild-to-moderate alzheimer's disease |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20060020042A1 (pt) |
| EP (1) | EP1703902B1 (pt) |
| AT (1) | ATE486592T1 (pt) |
| AU (1) | AU2005204358B2 (pt) |
| CA (1) | CA2551689A1 (pt) |
| CY (1) | CY1111359T1 (pt) |
| DE (1) | DE602005024511D1 (pt) |
| DK (1) | DK1703902T3 (pt) |
| HR (1) | HRP20110035T1 (pt) |
| IL (1) | IL176689A0 (pt) |
| NZ (1) | NZ548327A (pt) |
| PL (1) | PL1703902T3 (pt) |
| PT (1) | PT1703902E (pt) |
| RS (1) | RS51540B (pt) |
| RU (1) | RU2371173C2 (pt) |
| SI (1) | SI1703902T1 (pt) |
| WO (1) | WO2005067908A2 (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
| DE602006016934D1 (de) | 2005-04-06 | 2010-10-28 | Adamas Pharmaceuticals Inc | Verfahren und zusammensetzungen zur behandlung von zns-erkrankungen |
| US20100143341A1 (en) * | 2005-06-22 | 2010-06-10 | Develogen Aktiengesellschaft | Thienopyrimidines for pharmaceutical compositions |
| EP2004656B1 (en) * | 2006-04-07 | 2013-07-10 | Boehringer Ingelheim International GmbH | Thienopyrimidines having mnk1 /mnk2 inhibiting activity for pharmaceutical compositions |
| EP1889847A1 (en) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidines for pharmaceutical compositions |
| CN101516401A (zh) * | 2006-08-21 | 2009-08-26 | 诺瓦提斯公司 | 阿尔茨海默病进展的生物标记 |
| US20080182908A1 (en) * | 2007-01-25 | 2008-07-31 | Vinita Umashankar Vyas | Pharmaceutical compositions comprising memantine |
| EP2219649A2 (en) * | 2007-11-22 | 2010-08-25 | Boehringer Ingelheim International Gmbh | Use of mnk inhibitors for the treatment of alzheimer's disease |
| CA2735361A1 (en) | 2008-08-26 | 2010-03-04 | Boehringer Ingelheim International Gmbh | Thienopyrimidines for pharmaceutical compositions |
| WO2011041198A1 (en) | 2009-09-30 | 2011-04-07 | Transtech Pharma, Inc. | Substituted imidazole derivatives for treatment of alzheimers disease |
| UY33241A (es) * | 2010-02-26 | 2011-09-30 | Boehringer Ingelheim Int | ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?. |
| AR080328A1 (es) * | 2010-02-26 | 2012-03-28 | Boehringer Ingelheim Int | Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros |
| AU2011219758A1 (en) * | 2010-02-26 | 2012-08-16 | Boehringer Ingelheim International Gmbh | 4 - [cycloalkyloxy (hetero) arylamino] thieno [2, 3 - d] pyrimidines having Mnkl/ Mnk2 inhibiting activity for pharmaceutical compositions |
| WO2013043597A1 (en) * | 2011-09-19 | 2013-03-28 | The Feinstein Institute For Medical Research | Identification and uses of brain activity networks |
| JP5404750B2 (ja) * | 2011-11-22 | 2014-02-05 | シャープ株式会社 | 認知症ケア支援方法、認知症情報出力装置、認知症ケア支援システム、及びコンピュータプログラム |
| FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
| WO2014015047A1 (en) | 2012-07-17 | 2014-01-23 | The General Hospital Corporation | Compositions and methods to treat neurodegenerative diseases |
| US9717710B2 (en) | 2012-10-05 | 2017-08-01 | Vtv Therapeutics Llc | Treatment of mild and moderate Alzheimer's disease |
| WO2015006643A2 (en) * | 2013-07-12 | 2015-01-15 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
| WO2019190823A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
| WO2019190822A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
| JP7464591B2 (ja) | 2018-10-10 | 2024-04-09 | ブイティーブイ・セラピューティクス・エルエルシー | ［３－（４－｛２－ブチル－１－［４－（４－クロロ－フェノキシ）－フェニル］－１ｈ－イミダゾール－４－イル｝－フェノキシ）－プロピル］－ジエチル－アミンの代謝産物 |
| BR112021014576A2 (pt) | 2019-01-25 | 2021-10-05 | Brown University | Composições e métodos para tratamento, prevenção ou reversão de inflamação e distúrbios associados à idade |
| US20210002650A1 (en) * | 2019-07-03 | 2021-01-07 | University Of Virginia Patent Foundation | Compositions and methods for treating alzheimer's disease |
| KR102271305B1 (ko) * | 2020-05-21 | 2021-06-30 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
| WO2022025785A1 (ru) | 2020-07-29 | 2022-02-03 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Фармацевтическая композиция, включающая мемантин и цитиколин |
| KR102272907B1 (ko) * | 2020-11-05 | 2021-07-05 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
| WO2023248206A1 (en) * | 2022-06-24 | 2023-12-28 | Aribio Co., Ltd. | Compositions and methods for preventing and treating neurodegenerative diseases |
| WO2024003784A1 (en) * | 2022-06-29 | 2024-01-04 | Aribio Co., Ltd. | Composition for preventing and treating neurodegenerative diseases |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES413944A1 (es) * | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
| DE2856393C2 (de) * | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
| US5506231A (en) * | 1989-03-31 | 1996-04-09 | The Children's Medical Center Corporation | Treatment of aids dementia, myelopathy and blindness |
| US5334618A (en) * | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| ES2059602T3 (es) * | 1989-04-14 | 1994-11-16 | Merz & Co Gmbh & Co | Uso de derivados de adamantano para la prevencion y tratamiento de isquemia cerebral. |
| US5614560A (en) * | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| US5958919A (en) * | 1996-09-20 | 1999-09-28 | Washington University | Treatment of presymptomatic alzheimer's disease to prevent neuronal degeneration |
| GEP20032995B (en) * | 1997-06-30 | 2003-06-25 | Merz & Co Gmbh & Co | 1-Amino-Alkylcyclohexane NMDA Receptor Antagonists |
| US20040102525A1 (en) * | 2002-05-22 | 2004-05-27 | Kozachuk Walter E. | Compositions and methods of treating neurological disease and providing neuroprotection |
| AU2003227516B2 (en) * | 2002-05-31 | 2008-03-20 | H. Lundbeck A/S | A combination of an NMDA-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease |
| TW200418446A (en) * | 2002-10-24 | 2004-10-01 | Merz Pharma Gmbh & Co Kgaa | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors |
| WO2004071431A2 (en) * | 2003-02-05 | 2004-08-26 | Myriad Genetics, Inc. | Method and composition for treating neurodegenerative disorders |
-
2005
- 2005-01-05 AT AT05711256T patent/ATE486592T1/de active
- 2005-01-05 PT PT05711256T patent/PT1703902E/pt unknown
- 2005-01-05 US US11/030,584 patent/US20060020042A1/en not_active Abandoned
- 2005-01-05 CA CA002551689A patent/CA2551689A1/en not_active Abandoned
- 2005-01-05 DE DE602005024511T patent/DE602005024511D1/de active Active
- 2005-01-05 SI SI200531209T patent/SI1703902T1/sl unknown
- 2005-01-05 NZ NZ548327A patent/NZ548327A/en unknown
- 2005-01-05 EP EP05711256A patent/EP1703902B1/en not_active Revoked
- 2005-01-05 RU RU2007129842/14A patent/RU2371173C2/ru active
- 2005-01-05 WO PCT/US2005/000145 patent/WO2005067908A2/en active Application Filing
- 2005-01-05 DK DK05711256.7T patent/DK1703902T3/da active
- 2005-01-05 AU AU2005204358A patent/AU2005204358B2/en not_active Revoked
- 2005-01-05 PL PL05711256T patent/PL1703902T3/pl unknown
- 2005-01-05 RS RSP-2010/0561A patent/RS51540B/en unknown
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2006
- 2006-07-03 IL IL176689A patent/IL176689A0/en unknown
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2009
- 2009-10-29 US US12/608,046 patent/US20100048726A1/en not_active Abandoned
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2011
- 2011-01-04 CY CY20111100011T patent/CY1111359T1/el unknown
- 2011-01-18 HR HR20110035T patent/HRP20110035T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005204358A1 (en) | 2005-07-28 |
| US20100048726A1 (en) | 2010-02-25 |
| AU2005204358B2 (en) | 2008-09-04 |
| RS51540B (en) | 2011-06-30 |
| WO2005067908A2 (en) | 2005-07-28 |
| EP1703902B1 (en) | 2010-11-03 |
| PT1703902E (pt) | 2010-11-17 |
| RU2007129842A (ru) | 2009-02-10 |
| NZ548327A (en) | 2009-06-26 |
| HRP20110035T1 (hr) | 2011-02-28 |
| DE602005024511D1 (de) | 2010-12-16 |
| RU2371173C2 (ru) | 2009-10-27 |
| WO2005067908A3 (en) | 2005-11-10 |
| ATE486592T1 (de) | 2010-11-15 |
| EP1703902A2 (en) | 2006-09-27 |
| DK1703902T3 (da) | 2011-02-14 |
| US20060020042A1 (en) | 2006-01-26 |
| PL1703902T3 (pl) | 2011-04-29 |
| CY1111359T1 (el) | 2015-08-05 |
| IL176689A0 (en) | 2006-10-31 |
| SI1703902T1 (sl) | 2011-02-28 |
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