ATE486592T1 - Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer - Google Patents
Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimerInfo
- Publication number
- ATE486592T1 ATE486592T1 AT05711256T AT05711256T ATE486592T1 AT E486592 T1 ATE486592 T1 AT E486592T1 AT 05711256 T AT05711256 T AT 05711256T AT 05711256 T AT05711256 T AT 05711256T AT E486592 T1 ATE486592 T1 AT E486592T1
- Authority
- AT
- Austria
- Prior art keywords
- mild
- disease
- memantine
- treatment
- moderate alzheimer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53455304P | 2004-01-05 | 2004-01-05 | |
US54217604P | 2004-02-04 | 2004-02-04 | |
PCT/US2005/000145 WO2005067908A2 (en) | 2004-01-05 | 2005-01-05 | Memantine for the treatment of mild and mild-to-moderate alzheimer’s disease |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE486592T1 true ATE486592T1 (de) | 2010-11-15 |
Family
ID=34798833
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05711256T ATE486592T1 (de) | 2004-01-05 | 2005-01-05 | Memantin für die behandlung von leichtem bis mittelschwerem morbus alzheimer |
Country Status (17)
Country | Link |
---|---|
US (2) | US20060020042A1 (de) |
EP (1) | EP1703902B1 (de) |
AT (1) | ATE486592T1 (de) |
AU (1) | AU2005204358B2 (de) |
CA (1) | CA2551689A1 (de) |
CY (1) | CY1111359T1 (de) |
DE (1) | DE602005024511D1 (de) |
DK (1) | DK1703902T3 (de) |
HR (1) | HRP20110035T1 (de) |
IL (1) | IL176689A0 (de) |
NZ (1) | NZ548327A (de) |
PL (1) | PL1703902T3 (de) |
PT (1) | PT1703902E (de) |
RS (1) | RS51540B (de) |
RU (1) | RU2371173C2 (de) |
SI (1) | SI1703902T1 (de) |
WO (1) | WO2005067908A2 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
WO2006121560A2 (en) | 2005-04-06 | 2006-11-16 | Adamas Pharmaceuticals, Inc. | Methods and compositions for treatment of cns disorders |
CA2655799A1 (en) * | 2005-06-22 | 2006-12-28 | Develogen Aktiengesellschaft | Thienopyrimidines for pharmaceutical compositions |
EP2004656B1 (de) * | 2006-04-07 | 2013-07-10 | Boehringer Ingelheim International GmbH | Thienopyrimidine mit mnk1/mnk2-hemmender wirkung für pharmazeutische zusammensetzungen |
EP1889847A1 (de) * | 2006-07-10 | 2008-02-20 | DeveloGen Aktiengesellschaft | Pyrrolopyrimidine zur pharmazeutischen Anwendung |
KR20090041447A (ko) * | 2006-08-21 | 2009-04-28 | 노파르티스 아게 | 알츠하이머 질환 진행에 대한 바이오마커 |
US20080182908A1 (en) * | 2007-01-25 | 2008-07-31 | Vinita Umashankar Vyas | Pharmaceutical compositions comprising memantine |
WO2009065596A2 (en) * | 2007-11-22 | 2009-05-28 | Develogen Aktiengesellschaft | Use of mnk inhibitors for the treatment of alzheimer's disease |
CA2735361A1 (en) | 2008-08-26 | 2010-03-04 | Boehringer Ingelheim International Gmbh | Thienopyrimidines for pharmaceutical compositions |
US8580833B2 (en) | 2009-09-30 | 2013-11-12 | Transtech Pharma, Inc. | Substituted imidazole derivatives and methods of use thereof |
AR080328A1 (es) * | 2010-02-26 | 2012-03-28 | Boehringer Ingelheim Int | Tienopirimidinas que contienen un grupo alquilo sustituido inhibidoras de quinasas mnk1 y/o mnk2, composiciones farmaceuticas que las contienen y uso de las mismas para el tratamiento de trastornos metabolicos tales como diabetes y obesidad, y trastornos hiperproliferativos, entre otros |
MX2012009735A (es) * | 2010-02-26 | 2012-09-12 | Boehringer Ingelheim Int | 4-[cicloalquiloxi (hetero) arilamino] tieno [2,3-d] pirimidinas que tienen actividad inhibitoria de mnk1/mnk2 para composiciones farmaceuticas. |
UY33241A (es) * | 2010-02-26 | 2011-09-30 | Boehringer Ingelheim Int | ?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?. |
WO2013043597A1 (en) * | 2011-09-19 | 2013-03-28 | The Feinstein Institute For Medical Research | Identification and uses of brain activity networks |
JP5404750B2 (ja) * | 2011-11-22 | 2014-02-05 | シャープ株式会社 | 認知症ケア支援方法、認知症情報出力装置、認知症ケア支援システム、及びコンピュータプログラム |
FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
WO2014015047A1 (en) | 2012-07-17 | 2014-01-23 | The General Hospital Corporation | Compositions and methods to treat neurodegenerative diseases |
US9717710B2 (en) | 2012-10-05 | 2017-08-01 | Vtv Therapeutics Llc | Treatment of mild and moderate Alzheimer's disease |
EP3019865A4 (de) * | 2013-07-12 | 2017-04-05 | Immuneering Corporation | Systeme, verfahren und umgebung zur automatisierten überprüfung von genomdaten zur identifikation einer herunterregulierten und/oder unregulierten genexpression als zeichen einer erkrankung oder eines leidens |
WO2019190822A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
WO2019190823A1 (en) | 2018-03-28 | 2019-10-03 | Vtv Therapeutics Llc | Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine |
EP3864008A1 (de) | 2018-10-10 | 2021-08-18 | vTv Therapeutics LLC | Metaboliten von [3-(4-{2-butyl-l-[4-(4-chloro-phenoxy)-phenyl]-lh-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amin |
MX2021008751A (es) * | 2019-01-25 | 2021-11-12 | Univ Brown | Composiciones y metodos para tratar, prevenir o revertir la inflamacion y los trastornos asociados a la edad. |
US20210002650A1 (en) * | 2019-07-03 | 2021-01-07 | University Of Virginia Patent Foundation | Compositions and methods for treating alzheimer's disease |
KR102271305B1 (ko) * | 2020-05-21 | 2021-06-30 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
EP4190319A4 (de) | 2020-07-29 | 2024-05-01 | Novamedica Limited Liability Company | Pharmazeutische zusammensetzung mit memantin und citicolin |
KR102272907B1 (ko) * | 2020-11-05 | 2021-07-05 | 주식회사 아리바이오 | 치매 예방 및 치료용 조성물 |
WO2023248206A1 (en) * | 2022-06-24 | 2023-12-28 | Aribio Co., Ltd. | Compositions and methods for preventing and treating neurodegenerative diseases |
WO2024003784A1 (en) * | 2022-06-29 | 2024-01-04 | Aribio Co., Ltd. | Composition for preventing and treating neurodegenerative diseases |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA974518A (en) * | 1972-04-20 | 1975-09-16 | Merz And Co. | Procedure for the manufacture of 1,3,5 trisubstituted adamantan compounds |
DE2856393C2 (de) * | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
US5506231A (en) * | 1989-03-31 | 1996-04-09 | The Children's Medical Center Corporation | Treatment of aids dementia, myelopathy and blindness |
US5334618A (en) * | 1991-04-04 | 1994-08-02 | The Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
DE10299048I2 (de) * | 1989-04-14 | 2006-07-13 | Merz Pharma Gmbh & Co Kgaa | Verwendung von Adamantan-Derivaten zur Pr{vention und Behandlung der cerebralen Isch{mie |
US5614560A (en) * | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
US5958919A (en) * | 1996-09-20 | 1999-09-28 | Washington University | Treatment of presymptomatic alzheimer's disease to prevent neuronal degeneration |
TW593225B (en) * | 1997-06-30 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane NMDA receptor antagonists |
US20040102525A1 (en) * | 2002-05-22 | 2004-05-27 | Kozachuk Walter E. | Compositions and methods of treating neurological disease and providing neuroprotection |
DE60324788D1 (de) * | 2002-05-31 | 2009-01-02 | Lundbeck & Co As H | Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit |
GEP20094759B (en) * | 2002-10-24 | 2009-08-25 | Merz Pharma Gmbh & Co Kgaa | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors |
EP1603548A4 (de) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen |
-
2005
- 2005-01-05 RU RU2007129842/14A patent/RU2371173C2/ru active
- 2005-01-05 AU AU2005204358A patent/AU2005204358B2/en not_active Revoked
- 2005-01-05 AT AT05711256T patent/ATE486592T1/de active
- 2005-01-05 US US11/030,584 patent/US20060020042A1/en not_active Abandoned
- 2005-01-05 EP EP05711256A patent/EP1703902B1/de not_active Revoked
- 2005-01-05 RS RSP-2010/0561A patent/RS51540B/en unknown
- 2005-01-05 WO PCT/US2005/000145 patent/WO2005067908A2/en active Application Filing
- 2005-01-05 PT PT05711256T patent/PT1703902E/pt unknown
- 2005-01-05 CA CA002551689A patent/CA2551689A1/en not_active Abandoned
- 2005-01-05 NZ NZ548327A patent/NZ548327A/en unknown
- 2005-01-05 DK DK05711256.7T patent/DK1703902T3/da active
- 2005-01-05 DE DE602005024511T patent/DE602005024511D1/de active Active
- 2005-01-05 SI SI200531209T patent/SI1703902T1/sl unknown
- 2005-01-05 PL PL05711256T patent/PL1703902T3/pl unknown
-
2006
- 2006-07-03 IL IL176689A patent/IL176689A0/en unknown
-
2009
- 2009-10-29 US US12/608,046 patent/US20100048726A1/en not_active Abandoned
-
2011
- 2011-01-04 CY CY20111100011T patent/CY1111359T1/el unknown
- 2011-01-18 HR HR20110035T patent/HRP20110035T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
US20100048726A1 (en) | 2010-02-25 |
US20060020042A1 (en) | 2006-01-26 |
EP1703902A2 (de) | 2006-09-27 |
WO2005067908A3 (en) | 2005-11-10 |
DE602005024511D1 (de) | 2010-12-16 |
PT1703902E (pt) | 2010-11-17 |
RS51540B (en) | 2011-06-30 |
DK1703902T3 (da) | 2011-02-14 |
HRP20110035T1 (hr) | 2011-02-28 |
PL1703902T3 (pl) | 2011-04-29 |
RU2007129842A (ru) | 2009-02-10 |
IL176689A0 (en) | 2006-10-31 |
CY1111359T1 (el) | 2015-08-05 |
CA2551689A1 (en) | 2005-07-28 |
WO2005067908A2 (en) | 2005-07-28 |
SI1703902T1 (sl) | 2011-02-28 |
RU2371173C2 (ru) | 2009-10-27 |
NZ548327A (en) | 2009-06-26 |
AU2005204358A1 (en) | 2005-07-28 |
EP1703902B1 (de) | 2010-11-03 |
AU2005204358B2 (en) | 2008-09-04 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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