CA2551305C - Method and apparatus for efficient thin film fluid processing of flat surfaces - Google Patents

Method and apparatus for efficient thin film fluid processing of flat surfaces Download PDF

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Publication number
CA2551305C
CA2551305C CA2551305A CA2551305A CA2551305C CA 2551305 C CA2551305 C CA 2551305C CA 2551305 A CA2551305 A CA 2551305A CA 2551305 A CA2551305 A CA 2551305A CA 2551305 C CA2551305 C CA 2551305C
Authority
CA
Canada
Prior art keywords
fluid
gas permeable
substrate
liquid reagent
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2551305A
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English (en)
French (fr)
Other versions
CA2551305A1 (en
Inventor
Brian H. Kram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ventana Medical Systems Inc
Original Assignee
Ventana Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Medical Systems Inc filed Critical Ventana Medical Systems Inc
Publication of CA2551305A1 publication Critical patent/CA2551305A1/en
Application granted granted Critical
Publication of CA2551305C publication Critical patent/CA2551305C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2551305A 2003-12-23 2004-12-17 Method and apparatus for efficient thin film fluid processing of flat surfaces Expired - Lifetime CA2551305C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53206303P 2003-12-23 2003-12-23
US60/532,063 2003-12-23
PCT/US2004/042864 WO2005064309A1 (en) 2003-12-23 2004-12-17 Method and apparatus for efficient thin film fluid

Publications (2)

Publication Number Publication Date
CA2551305A1 CA2551305A1 (en) 2005-07-14
CA2551305C true CA2551305C (en) 2013-08-13

Family

ID=34738738

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2551305A Expired - Lifetime CA2551305C (en) 2003-12-23 2004-12-17 Method and apparatus for efficient thin film fluid processing of flat surfaces

Country Status (5)

Country Link
US (2) US7615371B2 (https=)
EP (1) EP1697719B1 (https=)
JP (1) JP4871737B2 (https=)
CA (1) CA2551305C (https=)
WO (1) WO2005064309A1 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7501283B2 (en) * 2003-08-11 2009-03-10 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
US7744817B2 (en) 2003-08-11 2010-06-29 Sakura Finetek U.S.A., Inc. Manifold assembly
US7767152B2 (en) 2003-08-11 2010-08-03 Sakura Finetek U.S.A., Inc. Reagent container and slide reaction retaining tray, and method of operation
US9518899B2 (en) 2003-08-11 2016-12-13 Sakura Finetek U.S.A., Inc. Automated reagent dispensing system and method of operation
WO2005064309A1 (en) * 2003-12-23 2005-07-14 Ventana Medical Systems, Inc. Method and apparatus for efficient thin film fluid
WO2006012498A1 (en) * 2004-07-23 2006-02-02 Ventana Medical Systems, Inc. Method and apparatus for applying fluids to a biological sample
US8034610B2 (en) 2005-04-21 2011-10-11 Celerus Diagnostics, Inc. Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry
US8459509B2 (en) 2006-05-25 2013-06-11 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
WO2009085842A1 (en) * 2007-12-21 2009-07-09 Ventana Medical Systems, Inc. Relative-translational liquid application and removal
US9498791B2 (en) 2009-11-13 2016-11-22 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
JP5611363B2 (ja) 2009-11-13 2014-10-22 ベンタナ メディカル システムズ， インコーポレイテッド 調整可能な体積を収容する薄膜処理装置
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2012048154A1 (en) 2010-10-06 2012-04-12 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
JP5801410B2 (ja) 2010-11-10 2015-10-28 コンスティテューション・メディカル・インコーポレイテッドＣｏｎｓｔｉｔｕｔｉｏｎ Ｍｅｄｉｃａｌ， Ｉｎｃ． 検査用に生物試料を準備するための自動化されたシステムおよび方法
US8752732B2 (en) 2011-02-01 2014-06-17 Sakura Finetek U.S.A., Inc. Fluid dispensing system
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
US8932543B2 (en) * 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
US8580568B2 (en) 2011-09-21 2013-11-12 Sakura Finetek U.S.A., Inc. Traceability for automated staining system
WO2013079606A1 (en) 2011-12-01 2013-06-06 Ventana Medical Systems, Inc. Automated dual stain of mirna and protein targets
US10778913B2 (en) 2013-03-12 2020-09-15 Ventana Medical Systems, Inc. Digitally enhanced microscopy for multiplexed histology
CA2901513C (en) 2013-03-12 2020-12-29 Ventana Medical Systems, Inc. Proximity assay for in situ detection of targets
USD728120S1 (en) 2013-03-15 2015-04-28 Ventana Medical Systems, Inc. Arcuate member for moving liquids along a microscope slide
ES2939124T3 (es) 2013-04-05 2023-04-19 Roche Diagnostics Hematology Inc Sistemas y procedimientos automatizados para preparar muestras biológicas para su examen
US9121798B2 (en) 2013-08-26 2015-09-01 Rarecyte, Inc. Apparatus for spreading a fluid across a substrate and method of using the same
ES2533144B1 (es) * 2013-10-02 2016-05-12 Fundació Institut De Ciències Fotòniques Soporte ópticamente transparente para la obtención de especímenes de tipo fluido libres de burbujas
CN111089980B (zh) 2013-12-13 2023-08-15 文塔纳医疗系统公司 生物样本的自动化组织学处理及相关的技术
JP6071925B2 (ja) * 2014-03-03 2017-02-01 富士フイルム株式会社 有機半導体膜の形成方法および有機半導体膜の形成装置
US10634590B2 (en) 2014-03-11 2020-04-28 Emd Millipore Corporation IHC, tissue slide fluid exchange disposable and system
US10209166B2 (en) 2014-11-18 2019-02-19 Alfonso Heras System and method for processing biological specimens
US11280803B2 (en) 2016-11-22 2022-03-22 Sakura Finetek U.S.A., Inc. Slide management system
EP3631409B1 (en) 2017-05-24 2025-06-25 Ventana Medical Systems, Inc. Gas knife using parallelogram flow
EP3631410B1 (en) 2017-05-26 2024-08-28 Ventana Medical Systems, Inc. Non-contact, on-slide fluid mixing
TWI734453B (zh) * 2020-04-24 2021-07-21 元錦生物科技股份有限公司 用以調節液體分佈之容器及其方法
HU231596B1 (hu) * 2022-02-04 2025-03-28 3Dhistech Kft. Tárgylemez takaró eszköz, valamint inkubációs kamra, amely ilyen tárgylemez takaró eszközt tartalmaz

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US656974A (en) * 1900-04-13 1900-08-28 William H Higgins Detector-bar.
US3667896A (en) 1968-10-21 1972-06-06 Miles Lab Applying film of stain to tissue mounted on a moving slide
SE373963B (https=) 1973-06-14 1975-02-17 Janson Sven Olof
US3871895A (en) * 1973-06-29 1975-03-18 Technicon Instr Method for preparing smears of biological liquids
US3977568A (en) 1975-01-08 1976-08-31 Eastman Kodak Company Biological fluid dispenser for dispensing micro amounts
US4043292A (en) 1975-07-21 1977-08-23 Corning Glass Works Microscope slide staining apparatus having temperature control
CA1057592A (en) * 1975-12-19 1979-07-03 Technicon Instruments Corporation Transfer process and apparatus therefor
SE403940B (sv) 1976-02-26 1978-09-11 Cytologiska Centrallab Sett och anordning for maskinell applicering av teckplattor pa med preparat for mikroskopisk undersokning forsedda objektglas
US4092952A (en) 1977-08-19 1978-06-06 Wilkie Ronald N Automatic slide stainer
SE7801564L (sv) 1978-02-10 1979-08-11 Lkb Produkter Ab Anordning for infergning av biologiska preparat
DE2915248C3 (de) 1979-04-14 1982-01-14 Gise, Frhr. von, Hardo, Dr.med., 7400 Tübingen Einrichtung zum automatischen wahlweisen u. exakten Behandeln von Präparaten
US4296069A (en) 1980-06-16 1981-10-20 Eastman Kodak Company Apparatus for processing an analysis slide
US4384193A (en) 1981-06-09 1983-05-17 Immulok, Inc. Incubating device for specimen mounted on glass slides in immunoassays
US4430299A (en) 1981-06-18 1984-02-07 Coulter Electronics, Inc. Apparatus for monitoring chemical reactions
US4635791A (en) 1983-01-31 1987-01-13 Bio-Innovations Container package for staining biological specimens
US4629862A (en) 1984-03-28 1986-12-16 Olympus Optical Company Ltd. Sample heater for use in microscopes
DE8512517U1 (de) 1985-04-27 1985-06-13 Hastka, Jan, 6803 Edingen Einrichtung für zytologische und histologische Untersuchungen von Objektträgerpräparaten
US4858155A (en) 1985-12-24 1989-08-15 Beckman Instruments, Inc. Reaction temperature control system
US5154889A (en) 1986-08-07 1992-10-13 Fuji Photo Film Co., Ltd. Chemical analysis apparatus
US4847208A (en) 1987-07-29 1989-07-11 Bogen Steven A Apparatus for immunohistochemical staining and method of rinsing a plurality of slides
GB8722902D0 (en) 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US4865986A (en) 1988-10-06 1989-09-12 Coy Corporation Temperature control apparatus
FR2641436A1 (https=) 1988-12-30 1990-07-06 Labo Electronique Physique
US5225325A (en) * 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5075079A (en) 1990-05-21 1991-12-24 Technicon Instruments Corporation Slide analysis system
US5207987A (en) 1990-05-21 1993-05-04 Pb Diagnostic Systems Inc. Temperature controlled chamber for diagnostic analyzer
US5425918A (en) 1990-07-18 1995-06-20 Australian Biomedical Corporation Apparatus for automatic tissue staining for immunohistochemistry
DE69130205T2 (de) 1990-12-25 1999-03-25 Ngk Insulators, Ltd., Nagoya, Aichi Heizungsapparat für eine Halbleiterscheibe und Verfahren zum Herstellen desselben
US5696887A (en) 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
GB9123463D0 (en) 1991-11-05 1991-12-18 Hybaid Ltd Reaction temperature control device
US6180061B1 (en) 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
US20040191128A1 (en) 1992-05-11 2004-09-30 Cytologix Corporation Slide stainer with heating
US6092695A (en) 1992-05-11 2000-07-25 Cytologix Corporation Interchangeable liquid dispensing cartridge pump
US5316452A (en) 1992-05-11 1994-05-31 Gilbert Corporation Dispensing assembly with interchangeable cartridge pumps
US5947167A (en) 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5601141A (en) 1992-10-13 1997-02-11 Intelligent Automation Systems, Inc. High throughput thermal cycler
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
JP3051626B2 (ja) 1993-12-09 2000-06-12 富士写真フイルム株式会社 インキュベータ
CA2161224C (en) 1994-02-25 1999-02-02 Gerald Brinker Dissolution testing apparatus
US5523056A (en) 1994-04-29 1996-06-04 Johnson & Johnson Clinical Diagnostics, Inc. Twin rotor incubator assembly
CA2156226C (en) * 1994-08-25 1999-02-23 Takayuki Taguchi Biological fluid analyzing device and method
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
JP3536501B2 (ja) * 1996-01-16 2004-06-14 東レ株式会社 複合半透膜の製造方法及びその装置
US6114122A (en) 1996-03-26 2000-09-05 Affymetrix, Inc. Fluidics station with a mounting system and method of using
AUPN923596A0 (en) * 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
JP3570817B2 (ja) * 1996-06-04 2004-09-29 株式会社千代田製作所 顕微鏡標本のカバーガラス取出し及び取付け方法
US5839091A (en) 1996-10-07 1998-11-17 Lab Vision Corporation Method and apparatus for automatic tissue staining
US5958341A (en) 1996-12-23 1999-09-28 American Registry Of Pathology Apparatus for efficient processing of tissue samples on slides
JPH10197424A (ja) * 1997-01-14 1998-07-31 Chiyoda Manufacturing Co Ltd 顕微鏡標本のカバーガラス取付け方法及び装置
SE517044C2 (sv) 1997-03-20 2002-04-09 Texo Ab Tygbomsarrangemang för vävmaskin
US5922604A (en) 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
US6050719A (en) 1998-01-30 2000-04-18 Affymetrix, Inc. Rotational mixing method using a cartridge having a narrow interior
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
JP3847559B2 (ja) 1998-02-27 2006-11-22 ベンタナ・メデイカル・システムズ・インコーポレーテツド 独立スライド加熱器を有する自動化分子病理学装置
US6096271A (en) 1998-02-27 2000-08-01 Cytologix Corporation Random access slide stainer with liquid waste segregation
US6183693B1 (en) 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US6495106B1 (en) 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
US6572830B1 (en) * 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
US6673620B1 (en) 1999-04-20 2004-01-06 Cytologix Corporation Fluid exchange in a chamber on a microscope slide
US6569674B1 (en) 1999-12-15 2003-05-27 Amersham Biosciences Ab Method and apparatus for performing biological reactions on a substrate surface
US6420114B1 (en) 1999-12-06 2002-07-16 Incyte Genomics, Inc. Microarray hybridization chamber
US6458526B1 (en) 2000-01-28 2002-10-01 Agilent Technologies, Inc. Method and apparatus to inhibit bubble formation in a fluid
DE10006084B4 (de) 2000-02-11 2009-01-02 Leica Biosystems Nussloch Gmbh Färbeautomat mit einer Heizstation
US6555365B2 (en) * 2000-12-07 2003-04-29 Biocrystal, Ltd. Microincubator comprising a cell culture apparatus and a transparent heater
US6485918B1 (en) 2001-07-02 2002-11-26 Packard Bioscience Corporation Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate
DK1499548T3 (da) * 2002-04-26 2008-09-01 Ventana Med Syst Inc Fremgangsmåde og apparat til automatiseret pålægning af dækglas
US7022157B2 (en) * 2003-11-12 2006-04-04 Agilent Technologies, Inc. Devices and methods for performing array based assays
JP4407271B2 (ja) * 2003-12-19 2010-02-03 株式会社日立製作所 チップ、反応分析装置、反応分析方法
WO2005064309A1 (en) * 2003-12-23 2005-07-14 Ventana Medical Systems, Inc. Method and apparatus for efficient thin film fluid

Also Published As

Publication number Publication date
US20090253592A1 (en) 2009-10-08
JP2007516447A (ja) 2007-06-21
US20050164374A1 (en) 2005-07-28
JP4871737B2 (ja) 2012-02-08
EP1697719A1 (en) 2006-09-06
WO2005064309A1 (en) 2005-07-14
US7615371B2 (en) 2009-11-10
EP1697719B1 (en) 2018-09-19
AU2004309825A1 (en) 2005-07-14
CA2551305A1 (en) 2005-07-14

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