CA2548349A1 - P ef-tu expression units - Google Patents

P ef-tu expression units Download PDF

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Publication number
CA2548349A1
CA2548349A1 CA002548349A CA2548349A CA2548349A1 CA 2548349 A1 CA2548349 A1 CA 2548349A1 CA 002548349 A CA002548349 A CA 002548349A CA 2548349 A CA2548349 A CA 2548349A CA 2548349 A1 CA2548349 A1 CA 2548349A1
Authority
CA
Canada
Prior art keywords
activity
nucleic acids
expression
acids encoding
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002548349A
Other languages
English (en)
French (fr)
Inventor
Burkhard Kroeger
Oskar Zelder
Corinna Klopprogge
Hartwig Schroeder
Stefan Haefner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2548349A1 publication Critical patent/CA2548349A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002548349A 2003-12-18 2004-12-15 P ef-tu expression units Abandoned CA2548349A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10359594.5 2003-12-18
DE10359594A DE10359594A1 (de) 2003-12-18 2003-12-18 PEF-TU-Expressionseinheiten
PCT/EP2004/014266 WO2005059093A2 (de) 2003-12-18 2004-12-15 P ef-tu-expressionseinheiten

Publications (1)

Publication Number Publication Date
CA2548349A1 true CA2548349A1 (en) 2005-06-30

Family

ID=34683543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002548349A Abandoned CA2548349A1 (en) 2003-12-18 2004-12-15 P ef-tu expression units

Country Status (19)

Country Link
US (2) US7785779B2 (OSRAM)
EP (2) EP1697525A2 (OSRAM)
JP (2) JP2007514425A (OSRAM)
KR (1) KR101162226B1 (OSRAM)
CN (2) CN101255419B (OSRAM)
AR (1) AR047150A1 (OSRAM)
AU (1) AU2004298546A1 (OSRAM)
BR (1) BRPI0417710A (OSRAM)
CA (1) CA2548349A1 (OSRAM)
DE (1) DE10359594A1 (OSRAM)
ES (1) ES2439946T3 (OSRAM)
IN (2) IN2006CH02598A (OSRAM)
MX (1) MXPA06006131A (OSRAM)
NO (1) NO20062683L (OSRAM)
PL (1) PL1908842T3 (OSRAM)
RU (1) RU2006125501A (OSRAM)
TW (1) TW200530398A (OSRAM)
WO (1) WO2005059093A2 (OSRAM)
ZA (1) ZA200605863B (OSRAM)

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DE10359594A1 (de) * 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
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DE102004061846A1 (de) 2004-12-22 2006-07-13 Basf Ag Mehrfachpromotoren
WO2008049781A1 (en) 2006-10-24 2008-05-02 Basf Se Method of reducing gene expression using modified codon usage
EP2431476B1 (en) 2007-02-19 2014-08-20 Evonik Degussa GmbH Coryneform bacteria with glycine cleavage activity
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
EP2348101B1 (en) 2008-10-20 2016-05-04 CJ CheilJedang Corporation Corynebacterium genus microorganism having ability to produce n-acetyl glucosamine and method for producing n-acetyl glucosamine or glucosamine using same
CN102753682A (zh) 2009-12-17 2012-10-24 巴斯夫欧洲公司 用于生产尸胺的方法和重组微生物
WO2012114256A1 (en) 2011-02-22 2012-08-30 Basf Se Processes and recombinant microorganisms for the production of cadaverine
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
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EP2861726B1 (en) 2012-06-18 2017-05-31 Evonik Degussa GmbH Recombinant microorganism for the fermentative production of methionine
KR20140066553A (ko) 2012-11-23 2014-06-02 삼성전자주식회사 코리네박테리움 속 균주의 신규 프로모터
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CN108026516A (zh) 2015-08-07 2018-05-11 赢创德固赛有限公司 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产
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US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
EP3415622A1 (en) 2017-06-14 2018-12-19 Evonik Degussa GmbH Method for production of fine chemicals using a corynebacterium secreting modified alpha-1,6-glucosidases
JP7498598B2 (ja) * 2020-05-29 2024-06-12 花王株式会社 新規プロモーター
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GB2621337A (en) 2022-08-08 2024-02-14 Mitsubishi Chemical Uk Ltd Process for the biological production of methacrylic acid and derivatives thereof
WO2025118096A1 (zh) * 2023-12-04 2025-06-12 武汉远大弘元股份有限公司 一种改造的强启动子、含其的菌株及它们在氨基酸生产中的应用
CN119331870A (zh) * 2024-11-11 2025-01-21 暨南大学 核酸分子、转录元件、表达载体、宿主及其应用

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Also Published As

Publication number Publication date
TW200530398A (en) 2005-09-16
US8044191B2 (en) 2011-10-25
EP1908842A3 (de) 2008-08-27
BRPI0417710A (pt) 2007-03-20
EP1908842B1 (de) 2013-09-18
CN101255419A (zh) 2008-09-03
ES2439946T3 (es) 2014-01-27
IN2008CH00415A (OSRAM) 2008-09-19
EP1697525A2 (de) 2006-09-06
AR047150A1 (es) 2006-01-11
CN101255419B (zh) 2012-06-20
AU2004298546A1 (en) 2005-06-30
MXPA06006131A (es) 2006-08-11
DE10359594A1 (de) 2005-07-28
JP2007514425A (ja) 2007-06-07
EP1908842A2 (de) 2008-04-09
PL1908842T3 (pl) 2014-03-31
KR101162226B1 (ko) 2012-07-04
IN2006CH02598A (OSRAM) 2007-06-08
US20080166775A1 (en) 2008-07-10
CN1894412A (zh) 2007-01-10
US7785779B2 (en) 2010-08-31
NO20062683L (no) 2006-09-11
KR20070000431A (ko) 2007-01-02
RU2006125501A (ru) 2008-01-27
JP5710095B2 (ja) 2015-04-30
WO2005059093A3 (de) 2006-03-02
US20080118948A1 (en) 2008-05-22
WO2005059093A2 (de) 2005-06-30
JP2008212155A (ja) 2008-09-18
ZA200605863B (en) 2008-01-30

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