CA2539670A1 - Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci - Google Patents

Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci Download PDF

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Publication number
CA2539670A1
CA2539670A1 CA002539670A CA2539670A CA2539670A1 CA 2539670 A1 CA2539670 A1 CA 2539670A1 CA 002539670 A CA002539670 A CA 002539670A CA 2539670 A CA2539670 A CA 2539670A CA 2539670 A1 CA2539670 A1 CA 2539670A1
Authority
CA
Canada
Prior art keywords
cells
diacrylate
polymer
monomer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002539670A
Other languages
English (en)
Inventor
Daniel G. Anderson
Shulamit Levenberg
Robert S. Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/843,707 external-priority patent/US20050019747A1/en
Application filed by Individual filed Critical Individual
Publication of CA2539670A1 publication Critical patent/CA2539670A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002539670A 2003-09-15 2004-09-15 Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci Abandoned CA2539670A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US50316503P 2003-09-15 2003-09-15
US60/503,165 2003-09-15
US57018704P 2004-05-12 2004-05-12
US10/843,707 US20050019747A1 (en) 2002-08-07 2004-05-12 Nanoliter-scale synthesis of arrayed biomaterials and screening thereof
US60/570,187 2004-05-12
US10/843,707 2004-05-12
PCT/US2004/030095 WO2005028619A2 (fr) 2003-09-15 2004-09-15 Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci

Publications (1)

Publication Number Publication Date
CA2539670A1 true CA2539670A1 (fr) 2005-03-31

Family

ID=34381975

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002539670A Abandoned CA2539670A1 (fr) 2003-09-15 2004-09-15 Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci

Country Status (3)

Country Link
EP (1) EP1675943A4 (fr)
CA (1) CA2539670A1 (fr)
WO (1) WO2005028619A2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006487B2 (en) 2005-06-15 2015-04-14 Massachusetts Institute Of Technology Amine-containing lipids and uses thereof
US20090203536A1 (en) * 2006-06-06 2009-08-13 Vermette Patrick Assay supports comprising a peg support, said support attached from a peg solution in cloud point (theta solvent) conditions
WO2009099539A2 (fr) * 2008-01-30 2009-08-13 Corning Incorporated Surfaces de (méth)acrylate de culture cellulaire, et procédé de fabrication et d'utilisation desdites surfaces
SG188098A1 (en) * 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived cardiomyocytes
US8354274B2 (en) 2008-01-30 2013-01-15 Geron Corporation Synthetic surfaces for culturing cells in chemically defined media
US8329469B2 (en) * 2008-01-30 2012-12-11 Geron Corporation Swellable (meth)acrylate surfaces for culturing cells in chemically defined media
CA2714010C (fr) 2008-01-30 2020-06-16 Corning Incorporated Surfaces synthetiques pour la culture de cellules progenitrices d'oligodendrocytes issues de cellules souches
CA2742954C (fr) 2008-11-07 2018-07-10 Massachusetts Institute Of Technology Lipidoides aminoalcool et leurs utilisations
WO2011014845A1 (fr) * 2009-07-31 2011-02-03 Nanoink, Inc. Système de criblage destiné à identifier des motifs sur des surfaces de substrats pour induire la différenciation des cellules souches et pour produire une population homogène d'un type de cellule recherché
PL3338765T3 (pl) 2009-12-01 2019-06-28 Translate Bio, Inc. Pochodna steroidowa dla dostarczania mrna w ludzkich chorobach genetycznych
US9193827B2 (en) 2010-08-26 2015-11-24 Massachusetts Institute Of Technology Poly(beta-amino alcohols), their preparation, and uses thereof
PL2691443T3 (pl) 2011-03-28 2021-08-30 Massachusetts Institute Of Technology Sprzężone lipomery i ich zastosowania
CN111671918A (zh) 2011-06-08 2020-09-18 川斯勒佰尔公司 Mrna递送的脂质纳米颗粒组合物和方法
US20150267192A1 (en) 2012-06-08 2015-09-24 Shire Human Genetic Therapies, Inc. Nuclease resistant polynucleotides and uses thereof
WO2014028487A1 (fr) 2012-08-13 2014-02-20 Massachusetts Institute Of Technology Lipidoïdes contenant des amines et leurs utilisations
ES2708561T3 (es) 2013-03-14 2019-04-10 Translate Bio Inc Métodos para la purificación de ARN mensajero
AU2014236305B2 (en) 2013-03-14 2019-01-17 Ethris Gmbh CFTR mRNA compositions and related methods and uses
WO2014179562A1 (fr) 2013-05-01 2014-11-06 Massachusetts Institute Of Technology Dérivés de 1,3,5-triazinane-2,4,6-trione et leurs utilisations
NZ718817A (en) 2013-10-22 2020-07-31 Massachusetts Inst Technology Lipid formulations for delivery of messenger rna
JP6506749B2 (ja) 2013-10-22 2019-04-24 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド フェニルケトン尿症のためのmRNA療法
CN106413811A (zh) 2013-10-22 2017-02-15 夏尔人类遗传性治疗公司 精氨基琥珀酸合成酶缺乏症的mrna疗法
ES2750661T3 (es) 2014-04-25 2020-03-26 Translate Bio Inc Métodos para la purificación de ARN mensajero
ES2750686T3 (es) 2014-05-30 2020-03-26 Translate Bio Inc Lípidos biodegradables para la administración de ácidos nucleicos
PE20171238A1 (es) 2014-06-24 2017-08-24 Shire Human Genetic Therapies Composiciones enriquecidas estereoquimicamente para administracion de acidos nucleicos
US9840479B2 (en) 2014-07-02 2017-12-12 Massachusetts Institute Of Technology Polyamine-fatty acid derived lipidoids and uses thereof
GB201416078D0 (en) * 2014-09-11 2014-10-29 Univ Nottingham Cell culture substrate
WO2018157154A2 (fr) 2017-02-27 2018-08-30 Translate Bio, Inc. Nouvel arnm cftr à codons optimisés
EP3624824B1 (fr) 2017-05-16 2024-07-10 Translate Bio, Inc. D'arnm à codons optimisés codant pour la cftr pour l'utilisation dans le traitement de la fibrose kystique
CN118421617A (zh) 2018-08-24 2024-08-02 川斯勒佰尔公司 用于纯化信使rna的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020142304A1 (en) * 2001-03-09 2002-10-03 Anderson Daniel G. Uses and methods of making microarrays of polymeric biomaterials
FR2825370A1 (fr) * 2001-05-31 2002-12-06 Inst Nat Sante Rech Med Keratinocytes obtenus a partir de cellules souches embryonnaires de mammiferes

Also Published As

Publication number Publication date
EP1675943A2 (fr) 2006-07-05
WO2005028619A3 (fr) 2005-09-09
EP1675943A4 (fr) 2007-12-05
WO2005028619A2 (fr) 2005-03-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued