CA2539670A1 - Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci - Google Patents
Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci Download PDFInfo
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- CA2539670A1 CA2539670A1 CA002539670A CA2539670A CA2539670A1 CA 2539670 A1 CA2539670 A1 CA 2539670A1 CA 002539670 A CA002539670 A CA 002539670A CA 2539670 A CA2539670 A CA 2539670A CA 2539670 A1 CA2539670 A1 CA 2539670A1
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- cells
- diacrylate
- polymer
- monomer
- cell
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- 238000001179 sorption measurement Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- CWXPZXBSDSIRCS-UHFFFAOYSA-N tert-butyl piperazine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCNCC1 CWXPZXBSDSIRCS-UHFFFAOYSA-N 0.000 description 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 125000001113 thiadiazolyl group Chemical group 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 125000004149 thio group Chemical group *S* 0.000 description 1
- 125000003396 thiol group Chemical class [H]S* 0.000 description 1
- BRNULMACUQOKMR-UHFFFAOYSA-N thiomorpholine Chemical compound C1CSCCN1 BRNULMACUQOKMR-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- 108091005957 yellow fluorescent proteins Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5073—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50316503P | 2003-09-15 | 2003-09-15 | |
| US60/503,165 | 2003-09-15 | ||
| US57018704P | 2004-05-12 | 2004-05-12 | |
| US10/843,707 US20050019747A1 (en) | 2002-08-07 | 2004-05-12 | Nanoliter-scale synthesis of arrayed biomaterials and screening thereof |
| US60/570,187 | 2004-05-12 | ||
| US10/843,707 | 2004-05-12 | ||
| PCT/US2004/030095 WO2005028619A2 (fr) | 2003-09-15 | 2004-09-15 | Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2539670A1 true CA2539670A1 (fr) | 2005-03-31 |
Family
ID=34381975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002539670A Abandoned CA2539670A1 (fr) | 2003-09-15 | 2004-09-15 | Synthese, a l'echelle du nanolitre, de biomateriaux en reseaux et criblage de ceux-ci |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1675943A4 (fr) |
| CA (1) | CA2539670A1 (fr) |
| WO (1) | WO2005028619A2 (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006487B2 (en) | 2005-06-15 | 2015-04-14 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| US20090203536A1 (en) * | 2006-06-06 | 2009-08-13 | Vermette Patrick | Assay supports comprising a peg support, said support attached from a peg solution in cloud point (theta solvent) conditions |
| WO2009099539A2 (fr) * | 2008-01-30 | 2009-08-13 | Corning Incorporated | Surfaces de (méth)acrylate de culture cellulaire, et procédé de fabrication et d'utilisation desdites surfaces |
| SG188098A1 (en) * | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
| US8354274B2 (en) | 2008-01-30 | 2013-01-15 | Geron Corporation | Synthetic surfaces for culturing cells in chemically defined media |
| US8329469B2 (en) * | 2008-01-30 | 2012-12-11 | Geron Corporation | Swellable (meth)acrylate surfaces for culturing cells in chemically defined media |
| CA2714010C (fr) | 2008-01-30 | 2020-06-16 | Corning Incorporated | Surfaces synthetiques pour la culture de cellules progenitrices d'oligodendrocytes issues de cellules souches |
| CA2742954C (fr) | 2008-11-07 | 2018-07-10 | Massachusetts Institute Of Technology | Lipidoides aminoalcool et leurs utilisations |
| WO2011014845A1 (fr) * | 2009-07-31 | 2011-02-03 | Nanoink, Inc. | Système de criblage destiné à identifier des motifs sur des surfaces de substrats pour induire la différenciation des cellules souches et pour produire une population homogène d'un type de cellule recherché |
| PL3338765T3 (pl) | 2009-12-01 | 2019-06-28 | Translate Bio, Inc. | Pochodna steroidowa dla dostarczania mrna w ludzkich chorobach genetycznych |
| US9193827B2 (en) | 2010-08-26 | 2015-11-24 | Massachusetts Institute Of Technology | Poly(beta-amino alcohols), their preparation, and uses thereof |
| PL2691443T3 (pl) | 2011-03-28 | 2021-08-30 | Massachusetts Institute Of Technology | Sprzężone lipomery i ich zastosowania |
| CN111671918A (zh) | 2011-06-08 | 2020-09-18 | 川斯勒佰尔公司 | Mrna递送的脂质纳米颗粒组合物和方法 |
| US20150267192A1 (en) | 2012-06-08 | 2015-09-24 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
| WO2014028487A1 (fr) | 2012-08-13 | 2014-02-20 | Massachusetts Institute Of Technology | Lipidoïdes contenant des amines et leurs utilisations |
| ES2708561T3 (es) | 2013-03-14 | 2019-04-10 | Translate Bio Inc | Métodos para la purificación de ARN mensajero |
| AU2014236305B2 (en) | 2013-03-14 | 2019-01-17 | Ethris Gmbh | CFTR mRNA compositions and related methods and uses |
| WO2014179562A1 (fr) | 2013-05-01 | 2014-11-06 | Massachusetts Institute Of Technology | Dérivés de 1,3,5-triazinane-2,4,6-trione et leurs utilisations |
| NZ718817A (en) | 2013-10-22 | 2020-07-31 | Massachusetts Inst Technology | Lipid formulations for delivery of messenger rna |
| JP6506749B2 (ja) | 2013-10-22 | 2019-04-24 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | フェニルケトン尿症のためのｍＲＮＡ療法 |
| CN106413811A (zh) | 2013-10-22 | 2017-02-15 | 夏尔人类遗传性治疗公司 | 精氨基琥珀酸合成酶缺乏症的mrna疗法 |
| ES2750661T3 (es) | 2014-04-25 | 2020-03-26 | Translate Bio Inc | Métodos para la purificación de ARN mensajero |
| ES2750686T3 (es) | 2014-05-30 | 2020-03-26 | Translate Bio Inc | Lípidos biodegradables para la administración de ácidos nucleicos |
| PE20171238A1 (es) | 2014-06-24 | 2017-08-24 | Shire Human Genetic Therapies | Composiciones enriquecidas estereoquimicamente para administracion de acidos nucleicos |
| US9840479B2 (en) | 2014-07-02 | 2017-12-12 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
| GB201416078D0 (en) * | 2014-09-11 | 2014-10-29 | Univ Nottingham | Cell culture substrate |
| WO2018157154A2 (fr) | 2017-02-27 | 2018-08-30 | Translate Bio, Inc. | Nouvel arnm cftr à codons optimisés |
| EP3624824B1 (fr) | 2017-05-16 | 2024-07-10 | Translate Bio, Inc. | D'arnm à codons optimisés codant pour la cftr pour l'utilisation dans le traitement de la fibrose kystique |
| CN118421617A (zh) | 2018-08-24 | 2024-08-02 | 川斯勒佰尔公司 | 用于纯化信使rna的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020142304A1 (en) * | 2001-03-09 | 2002-10-03 | Anderson Daniel G. | Uses and methods of making microarrays of polymeric biomaterials |
| FR2825370A1 (fr) * | 2001-05-31 | 2002-12-06 | Inst Nat Sante Rech Med | Keratinocytes obtenus a partir de cellules souches embryonnaires de mammiferes |
-
2004
- 2004-09-15 EP EP04788758A patent/EP1675943A4/fr not_active Withdrawn
- 2004-09-15 WO PCT/US2004/030095 patent/WO2005028619A2/fr active Application Filing
- 2004-09-15 CA CA002539670A patent/CA2539670A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1675943A2 (fr) | 2006-07-05 |
| WO2005028619A3 (fr) | 2005-09-09 |
| EP1675943A4 (fr) | 2007-12-05 |
| WO2005028619A2 (fr) | 2005-03-31 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |