CA2526883A1 - A pharmaceutical composition comprising a p2x7-receptor antagonist and a tumour necrosis factor .alpha. - Google Patents
A pharmaceutical composition comprising a p2x7-receptor antagonist and a tumour necrosis factor .alpha. Download PDFInfo
- Publication number
- CA2526883A1 CA2526883A1 CA002526883A CA2526883A CA2526883A1 CA 2526883 A1 CA2526883 A1 CA 2526883A1 CA 002526883 A CA002526883 A CA 002526883A CA 2526883 A CA2526883 A CA 2526883A CA 2526883 A1 CA2526883 A1 CA 2526883A1
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- CA
- Canada
- Prior art keywords
- ylmethyl
- tricyclo
- chloro
- dec
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 229940044551 receptor antagonist Drugs 0.000 title claims abstract description 46
- 239000002464 receptor antagonist Substances 0.000 title claims abstract description 46
- 102100037602 P2X purinoceptor 7 Human genes 0.000 title claims abstract description 22
- 101710189965 P2X purinoceptor 7 Proteins 0.000 title claims abstract description 22
- 102000018594 Tumour necrosis factor Human genes 0.000 title claims abstract description 12
- 108050007852 Tumour necrosis factor Proteins 0.000 title claims abstract description 12
- 239000008194 pharmaceutical composition Substances 0.000 title description 2
- 239000003112 inhibitor Substances 0.000 claims abstract description 48
- 239000004480 active ingredient Substances 0.000 claims abstract description 42
- 239000000825 pharmaceutical preparation Substances 0.000 claims abstract description 27
- 229940127557 pharmaceutical product Drugs 0.000 claims abstract description 27
- 238000011282 treatment Methods 0.000 claims abstract description 15
- 208000027866 inflammatory disease Diseases 0.000 claims abstract description 10
- YNZTXTGFUQRXMU-UHFFFAOYSA-N [2-(1-adamantylamino)-2-oxo-1-phenylethyl] propanoate Chemical group C1C(C2)CC(C3)CC2CC13NC(=O)C(OC(=O)CC)C1=CC=CC=C1 YNZTXTGFUQRXMU-UHFFFAOYSA-N 0.000 claims abstract description 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 55
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 36
- 150000001875 compounds Chemical class 0.000 claims description 32
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 32
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 30
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 26
- 229910052736 halogen Inorganic materials 0.000 claims description 24
- 150000002367 halogens Chemical class 0.000 claims description 24
- 229910052760 oxygen Inorganic materials 0.000 claims description 24
- -1 cyano, nitro, amino, hydroxyl Chemical group 0.000 claims description 23
- 125000001424 substituent group Chemical group 0.000 claims description 23
- 150000003839 salts Chemical class 0.000 claims description 22
- 229910052739 hydrogen Inorganic materials 0.000 claims description 21
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 18
- 239000001301 oxygen Substances 0.000 claims description 18
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 16
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- 125000005843 halogen group Chemical group 0.000 claims description 14
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- 125000000753 cycloalkyl group Chemical group 0.000 claims description 13
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- 125000001153 fluoro group Chemical group F* 0.000 claims description 8
- 150000002431 hydrogen Chemical class 0.000 claims description 8
- 125000002883 imidazolyl group Chemical group 0.000 claims description 8
- 125000000217 alkyl group Chemical group 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 125000001931 aliphatic group Chemical group 0.000 claims description 6
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 claims description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 6
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- 125000006528 (C2-C6) alkyl group Chemical group 0.000 claims description 4
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- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims description 2
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims description 2
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims description 2
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 claims description 2
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- 125000002618 bicyclic heterocycle group Chemical group 0.000 claims description 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 2
- 125000004122 cyclic group Chemical group 0.000 claims description 2
- 125000004981 cycloalkylmethyl group Chemical group 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 125000002950 monocyclic group Chemical group 0.000 claims description 2
- 125000002757 morpholinyl group Chemical group 0.000 claims description 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 2
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims description 2
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- 229920006395 saturated elastomer Polymers 0.000 claims description 2
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 6
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- CKSKCWVDDUDJMY-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[2-(2-hydroxyethylamino)ethoxymethyl]benzamide Chemical compound OCCNCCOCC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 CKSKCWVDDUDJMY-UHFFFAOYSA-N 0.000 claims 2
- WBTWKXHXQXPKJW-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[2-(3-hydroxypropylamino)ethylamino]benzamide Chemical compound OCCCNCCNC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 WBTWKXHXQXPKJW-UHFFFAOYSA-N 0.000 claims 2
- PNZXTKCHRSLEGQ-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[2-(3-hydroxypropylsulfonyl)ethoxy]benzamide Chemical compound OCCCS(=O)(=O)CCOC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 PNZXTKCHRSLEGQ-UHFFFAOYSA-N 0.000 claims 2
- CLJBWWGSUDMECB-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[2-[2-(1-methylimidazol-4-yl)ethylamino]ethylamino]benzamide Chemical compound CN1C=NC(CCNCCNC=2C=C(C(Cl)=CC=2)C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 CLJBWWGSUDMECB-UHFFFAOYSA-N 0.000 claims 2
- WXPRCUJBMDEYBY-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[2-[2-(2-hydroxyethylamino)ethoxy]ethoxy]benzamide Chemical compound OCCNCCOCCOC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 WXPRCUJBMDEYBY-UHFFFAOYSA-N 0.000 claims 2
- LHQVVDIEPGMAMY-UHFFFAOYSA-N n-(1-adamantylmethyl)-2-chloro-5-[3-(3-hydroxypropylamino)propoxy]benzamide Chemical compound OCCCNCCCOC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 LHQVVDIEPGMAMY-UHFFFAOYSA-N 0.000 claims 2
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- WPWSCNZLYJDLIU-SGGRRFJASA-N n-(1-adamantylmethyl)-2-chloro-5-[3-[[(2r)-1-hydroxypropan-2-yl]amino]propyl]benzamide Chemical compound OC[C@@H](C)NCCCC1=CC=C(Cl)C(C(=O)NCC23CC4CC(CC(C4)C2)C3)=C1 WPWSCNZLYJDLIU-SGGRRFJASA-N 0.000 claims 2
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- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 229940023080 viracept Drugs 0.000 description 1
- 239000003064 xanthine oxidase inhibitor Substances 0.000 description 1
- 229960001095 xylometazoline hydrochloride Drugs 0.000 description 1
- 229960004764 zafirlukast Drugs 0.000 description 1
- 229960002555 zidovudine Drugs 0.000 description 1
- MWLSOWXNZPKENC-SSDOTTSWSA-N zileuton Chemical compound C1=CC=C2SC([C@H](N(O)C(N)=O)C)=CC2=C1 MWLSOWXNZPKENC-SSDOTTSWSA-N 0.000 description 1
- 229960005332 zileuton Drugs 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0312321.3 | 2003-05-29 | ||
| GB0312321A GB0312321D0 (en) | 2003-05-29 | 2003-05-29 | New combination |
| SE0301655-7 | 2003-06-05 | ||
| SE0301655A SE0301655D0 (sv) | 2003-06-05 | 2003-06-05 | New combination |
| PCT/SE2004/000817 WO2004105798A1 (en) | 2003-05-29 | 2004-05-27 | A PHARMACEUTICAL COMPOSITION COMPRISING A P2X7-RECEPTOR ANTAGONIST AND A TUMOUR NECROSIS FACTOR α |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2526883A1 true CA2526883A1 (en) | 2004-12-09 |
Family
ID=33492248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002526883A Abandoned CA2526883A1 (en) | 2003-05-29 | 2004-05-27 | A pharmaceutical composition comprising a p2x7-receptor antagonist and a tumour necrosis factor .alpha. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070032465A1 (https=) |
| EP (1) | EP1633401A1 (https=) |
| JP (1) | JP2007501270A (https=) |
| KR (1) | KR20060037258A (https=) |
| AR (1) | AR044452A1 (https=) |
| BR (1) | BRPI0410739A (https=) |
| CA (1) | CA2526883A1 (https=) |
| CO (1) | CO5640094A2 (https=) |
| IS (1) | IS8188A (https=) |
| MX (1) | MXPA05012705A (https=) |
| NO (1) | NO20056131L (https=) |
| RU (1) | RU2350354C2 (https=) |
| TW (1) | TW200507829A (https=) |
| UY (1) | UY28335A1 (https=) |
| WO (1) | WO2004105798A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9538710B2 (en) | 2010-04-01 | 2017-01-10 | Tony Wayne Covely | Crop product tracking system and method |
| US10444122B2 (en) | 2010-04-01 | 2019-10-15 | Agri-Labs Holdings Llc | Soil sample tracking system and method |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0200920D0 (sv) * | 2002-03-25 | 2002-03-25 | Astrazeneca Ab | Novel compounds |
| SE0300480D0 (sv) | 2003-02-21 | 2003-02-21 | Astrazeneca Ab | Novel compounds |
| WO2004105797A1 (en) * | 2003-05-29 | 2004-12-09 | Astrazeneca Ab | A pharmaceutical composition comprising a p2x7 antagonist and sulfasalazine |
| EP1644042A1 (en) * | 2003-05-29 | 2006-04-12 | AstraZeneca AB | A pharmaceutical composition containing a p2x7 receptor antagonist and methotrexate |
| SE0302192D0 (sv) * | 2003-08-08 | 2003-08-08 | Astrazeneca Ab | Novel compounds |
| SE0302488D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | New combination |
| SA05260265A (ar) * | 2004-08-30 | 2005-12-03 | استرازينيكا ايه بي | مركبات جديدة |
| SE0402925D0 (sv) * | 2004-11-30 | 2004-11-30 | Astrazeneca Ab | Novel Compounds |
| WO2006095355A1 (en) * | 2005-03-07 | 2006-09-14 | Ganga Raju Gokaraju | Novel salts of boswellic acids and selectively enriched boswellic acids and processes for the same |
| GB0919594D0 (en) | 2009-11-09 | 2009-12-23 | Glaxo Group Ltd | Compounds |
| JP2013521002A (ja) | 2010-03-05 | 2013-06-10 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | 誘導樹状細胞組成物及びその使用 |
| CN103841969A (zh) * | 2011-08-04 | 2014-06-04 | 美国卫生和人力服务部 | 经由药物介导的对类二十烷酸平衡的操作治疗和预防微生物介导的疾病 |
| NZ701915A (en) | 2012-05-18 | 2016-11-25 | Genentech Inc | High-concentration monoclonal antibody formulations |
| KR102035463B1 (ko) * | 2018-02-14 | 2019-11-26 | 연세대학교 산학협력단 | 암 줄기세포의 치료용 약학 조성물 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3471491A (en) * | 1967-08-28 | 1969-10-07 | Squibb & Sons Inc | Adamantyl-s-triazines |
| US3464998A (en) * | 1968-03-04 | 1969-09-02 | Searle & Co | Adamantyl esters and amides of pyridinecarboxylic acids |
| US4349552A (en) * | 1978-10-30 | 1982-09-14 | Fujisawa Pharmaceutical Company, Ltd. | 5-Fluorouracil derivatives, and their pharmaceutical compositions |
| US4751292A (en) * | 1985-07-02 | 1988-06-14 | The Plant Cell Research Institute, Inc. | Adamantyl purines |
| US5399564A (en) * | 1991-09-03 | 1995-03-21 | Dowelanco | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides |
| EP0952832B1 (en) * | 1996-05-20 | 2008-08-27 | Darwin Discovery Limited | Quinoline carboxamides as tnf inhibitors and as pde-iv inhibitors |
| SE9704545D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
| SE9704544D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
| CN1147483C (zh) * | 1999-04-09 | 2004-04-28 | 阿斯特拉曾尼卡有限公司 | 金刚烷衍生物 |
| SE9904505D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Pharma Prod | Novel compounds |
| TWI258462B (en) * | 1999-12-17 | 2006-07-21 | Astrazeneca Ab | Adamantane derivative compounds, process for preparing the same and pharmaceutical composition comprising the same |
| GB0013737D0 (en) * | 2000-06-07 | 2000-07-26 | Astrazeneca Ab | Novel compounds |
| US8058441B2 (en) * | 2001-07-02 | 2011-11-15 | N.V. Organon | Tetrahydroquinoline derivatives |
| WO2003042190A1 (en) * | 2001-11-12 | 2003-05-22 | Pfizer Products Inc. | N-alkyl-adamantyl derivatives as p2x7-receptor antagonists |
| PA8557501A1 (es) * | 2001-11-12 | 2003-06-30 | Pfizer Prod Inc | Benzamida, heteroarilamida y amidas inversas |
| SE0103836D0 (sv) * | 2001-11-16 | 2001-11-16 | Astrazeneca Ab | Novel compounds |
| US6908939B2 (en) * | 2001-12-21 | 2005-06-21 | Galderma Research & Development S.N.C. | Biaromatic ligand activators of PPARγ receptors |
| SE0200920D0 (sv) * | 2002-03-25 | 2002-03-25 | Astrazeneca Ab | Novel compounds |
| SE0300445D0 (sv) * | 2003-02-18 | 2003-02-18 | Astrazeneca Ab | New combination |
| SE0300480D0 (sv) * | 2003-02-21 | 2003-02-21 | Astrazeneca Ab | Novel compounds |
| EP1644042A1 (en) * | 2003-05-29 | 2006-04-12 | AstraZeneca AB | A pharmaceutical composition containing a p2x7 receptor antagonist and methotrexate |
| WO2004105797A1 (en) * | 2003-05-29 | 2004-12-09 | Astrazeneca Ab | A pharmaceutical composition comprising a p2x7 antagonist and sulfasalazine |
| SE0302192D0 (sv) * | 2003-08-08 | 2003-08-08 | Astrazeneca Ab | Novel compounds |
| SE0302488D0 (sv) * | 2003-09-18 | 2003-09-18 | Astrazeneca Ab | New combination |
-
2004
- 2004-05-27 TW TW093115142A patent/TW200507829A/zh unknown
- 2004-05-27 WO PCT/SE2004/000817 patent/WO2004105798A1/en not_active Ceased
- 2004-05-27 MX MXPA05012705A patent/MXPA05012705A/es not_active Application Discontinuation
- 2004-05-27 US US10/558,354 patent/US20070032465A1/en not_active Abandoned
- 2004-05-27 JP JP2006532213A patent/JP2007501270A/ja active Pending
- 2004-05-27 KR KR1020057022669A patent/KR20060037258A/ko not_active Ceased
- 2004-05-27 RU RU2005136131/15A patent/RU2350354C2/ru not_active IP Right Cessation
- 2004-05-27 BR BRPI0410739-0A patent/BRPI0410739A/pt not_active IP Right Cessation
- 2004-05-27 EP EP04735147A patent/EP1633401A1/en not_active Withdrawn
- 2004-05-27 CA CA002526883A patent/CA2526883A1/en not_active Abandoned
- 2004-05-28 AR ARP040101848A patent/AR044452A1/es unknown
- 2004-05-28 UY UY28335A patent/UY28335A1/es unknown
-
2005
- 2005-11-24 CO CO05119402A patent/CO5640094A2/es not_active Application Discontinuation
- 2005-12-20 IS IS8188A patent/IS8188A/is unknown
- 2005-12-22 NO NO20056131A patent/NO20056131L/no not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9538710B2 (en) | 2010-04-01 | 2017-01-10 | Tony Wayne Covely | Crop product tracking system and method |
| US10444122B2 (en) | 2010-04-01 | 2019-10-15 | Agri-Labs Holdings Llc | Soil sample tracking system and method |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20060037258A (ko) | 2006-05-03 |
| US20070032465A1 (en) | 2007-02-08 |
| RU2005136131A (ru) | 2006-07-27 |
| CO5640094A2 (es) | 2006-05-31 |
| WO2004105798A1 (en) | 2004-12-09 |
| IS8188A (is) | 2005-12-20 |
| AU2004243137A1 (en) | 2004-12-09 |
| AR044452A1 (es) | 2005-09-14 |
| MXPA05012705A (es) | 2006-02-08 |
| RU2350354C2 (ru) | 2009-03-27 |
| JP2007501270A (ja) | 2007-01-25 |
| UY28335A1 (es) | 2004-12-31 |
| TW200507829A (en) | 2005-03-01 |
| EP1633401A1 (en) | 2006-03-15 |
| BRPI0410739A (pt) | 2006-06-27 |
| NO20056131L (no) | 2006-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |