CA2493646A1 - Caspase inhibitors and uses thereof - Google Patents
Caspase inhibitors and uses thereof Download PDFInfo
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- CA2493646A1 CA2493646A1 CA002493646A CA2493646A CA2493646A1 CA 2493646 A1 CA2493646 A1 CA 2493646A1 CA 002493646 A CA002493646 A CA 002493646A CA 2493646 A CA2493646 A CA 2493646A CA 2493646 A1 CA2493646 A1 CA 2493646A1
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- MRTGTFBFDWLFNS-UHFFFAOYSA-N tert-butyl 4-oxo-3-(phenylmethoxycarbonylamino)-5-(2,3,5,6-tetrafluorophenoxy)pentanoate Chemical compound FC=1C(F)=CC(F)=C(F)C=1OCC(=O)C(CC(=O)OC(C)(C)C)NC(=O)OCC1=CC=CC=C1 MRTGTFBFDWLFNS-UHFFFAOYSA-N 0.000 description 1
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Classifications
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Landscapes
- Health & Medical Sciences (AREA)
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- Public Health (AREA)
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Applications Claiming Priority (5)
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| US39259202P | 2002-06-28 | 2002-06-28 | |
| US60/392,592 | 2002-06-28 | ||
| US43507302P | 2002-12-20 | 2002-12-20 | |
| US60/435,073 | 2002-12-20 | ||
| PCT/US2003/020557 WO2004002961A1 (en) | 2002-06-28 | 2003-06-27 | Caspase inhibitors and uses thereof |
Publications (1)
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| CA2493646A1 true CA2493646A1 (en) | 2004-01-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002493646A Abandoned CA2493646A1 (en) | 2002-06-28 | 2003-06-27 | Caspase inhibitors and uses thereof |
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| JP (2) | JP4616643B2 (https=) |
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| PL374598A1 (en) | 2002-06-28 | 2005-10-31 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| US7612091B2 (en) | 2002-12-20 | 2009-11-03 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| PE20050159A1 (es) * | 2003-05-27 | 2005-04-19 | Vertex Pharma | Derivados de acido 3-[2-(3-amino-2-oxo-2h-piridin-1-il)-acetilamino]-4-oxo-pentanoico como inhibidores de caspasa |
| EP2399916B1 (en) * | 2004-03-12 | 2014-12-10 | Vertex Pharmaceuticals Incorporated | Process and intermediates for the preparation of aspartic acetal caspase ihnhibitors |
| WO2005115362A1 (en) * | 2004-05-15 | 2005-12-08 | Vertex Pharmaceuticals Incorporated | Treating seizures using ice inhibitors |
| CA2567080A1 (en) | 2004-05-27 | 2005-12-15 | Vertex Pharmaceuticals Incorporated | Ice inhibitors for the treatment of autoinflammatory diseases |
| EP3121176A1 (en) * | 2004-06-08 | 2017-01-25 | Families of Spinal Muscular Atrophy | 2,4-diaminoquinazolines for the treatment of spinal muscular atrophy |
| EP1784390A2 (en) * | 2004-08-13 | 2007-05-16 | Amgen Inc. | Substituted benzofused heterocycles |
| EP1791535B1 (en) | 2004-09-17 | 2008-07-30 | BioMAS Ltd. | Novel tellurium compounds and their use as immunomodulators |
| ATE543803T1 (de) * | 2004-11-24 | 2012-02-15 | Vertex Pharma | 3-ä2-(3-azylamino-2-oxo-2h-pyridin-1- yl)acetylaminoü-4-oxopentansäurederivate und deren verwendung als caspase-inhibitoren |
| EP1833803A4 (en) * | 2005-01-03 | 2009-08-05 | Myriad Genetics Inc | PHARMACEUTICAL COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCTORS OF APOPTOSIS AND THEIR USE |
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-
2003
- 2003-06-27 PL PL03374598A patent/PL374598A1/xx not_active Application Discontinuation
- 2003-06-27 BR BR0312232-8A patent/BR0312232A/pt not_active IP Right Cessation
- 2003-06-27 MX MXPA05000069A patent/MXPA05000069A/es unknown
- 2003-06-27 CN CNB038187930A patent/CN100503572C/zh not_active Expired - Fee Related
- 2003-06-27 RU RU2005102094/04A patent/RU2005102094A/ru unknown
- 2003-06-27 JP JP2004518103A patent/JP4616643B2/ja not_active Expired - Fee Related
- 2003-06-27 CA CA002493646A patent/CA2493646A1/en not_active Abandoned
- 2003-06-27 AR ARP030102352A patent/AR040350A1/es unknown
- 2003-06-27 WO PCT/US2003/020557 patent/WO2004002961A1/en not_active Ceased
- 2003-06-27 PE PE2003000653A patent/PE20040728A1/es not_active Application Discontinuation
- 2003-06-27 KR KR10-2004-7021300A patent/KR20050013260A/ko not_active Ceased
- 2003-06-27 IL IL16598603A patent/IL165986A0/xx unknown
- 2003-06-27 US US10/609,147 patent/US7553852B2/en not_active Expired - Fee Related
- 2003-06-27 TW TW092117681A patent/TW200404783A/zh unknown
- 2003-06-27 NZ NZ537807A patent/NZ537807A/en unknown
- 2003-06-27 EP EP03762231A patent/EP1539701A1/en not_active Withdrawn
- 2003-06-27 AU AU2003248758A patent/AU2003248758A1/en not_active Abandoned
- 2003-06-30 UY UY27872A patent/UY27872A1/es unknown
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2005
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2009
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2010
- 2010-02-04 JP JP2010023632A patent/JP2010143942A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN100503572C (zh) | 2009-06-24 |
| RU2005102094A (ru) | 2006-02-27 |
| PE20040728A1 (es) | 2004-10-23 |
| US20090281128A1 (en) | 2009-11-12 |
| JP4616643B2 (ja) | 2011-01-19 |
| NZ537807A (en) | 2007-05-31 |
| US8129381B2 (en) | 2012-03-06 |
| JP2010143942A (ja) | 2010-07-01 |
| PL374598A1 (en) | 2005-10-31 |
| JP2005533825A (ja) | 2005-11-10 |
| KR20050013260A (ko) | 2005-02-03 |
| US7553852B2 (en) | 2009-06-30 |
| NO20050851L (no) | 2005-03-29 |
| UY27872A1 (es) | 2003-12-31 |
| TW200404783A (en) | 2004-04-01 |
| BR0312232A (pt) | 2005-05-10 |
| EP1539701A1 (en) | 2005-06-15 |
| CN1675184A (zh) | 2005-09-28 |
| IL165986A0 (en) | 2006-01-15 |
| AU2003248758A1 (en) | 2004-01-19 |
| AR040350A1 (es) | 2005-03-30 |
| MXPA05000069A (es) | 2005-04-11 |
| US20040072850A1 (en) | 2004-04-15 |
| WO2004002961A1 (en) | 2004-01-08 |
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| EEER | Examination request | ||
| FZDE | Discontinued |