CA2488220C - Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol - Google Patents

Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol Download PDF

Info

Publication number
CA2488220C
CA2488220C CA2488220A CA2488220A CA2488220C CA 2488220 C CA2488220 C CA 2488220C CA 2488220 A CA2488220 A CA 2488220A CA 2488220 A CA2488220 A CA 2488220A CA 2488220 C CA2488220 C CA 2488220C
Authority
CA
Canada
Prior art keywords
dimethylamino
methylpentan
methoxyphenyl
pharmaceutical formulation
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2488220A
Other languages
English (en)
French (fr)
Other versions
CA2488220A1 (en
Inventor
Johannes Bartholomause
Iris Ziegler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grünenthal GmbH
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of CA2488220A1 publication Critical patent/CA2488220A1/en
Application granted granted Critical
Publication of CA2488220C publication Critical patent/CA2488220C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2488220A 2002-05-29 2003-05-26 Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol Expired - Fee Related CA2488220C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10224108A DE10224108A1 (de) 2002-05-29 2002-05-29 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes Arzneimiitel mit verzögerter Wirkstofffreisetzung
DE10224108.2 2002-05-29
PCT/EP2003/005488 WO2003099267A1 (de) 2002-05-29 2003-05-26 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes arzneimittel mit verzögerter wirkstofffreisetzung

Publications (2)

Publication Number Publication Date
CA2488220A1 CA2488220A1 (en) 2003-12-04
CA2488220C true CA2488220C (en) 2011-02-01

Family

ID=29557413

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2488220A Expired - Fee Related CA2488220C (en) 2002-05-29 2003-05-26 Medicament with delayed active constituent release containing 1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol

Country Status (14)

Country Link
EP (1) EP1507519B1 (enExample)
JP (1) JP5459818B2 (enExample)
AR (1) AR039900A1 (enExample)
AT (1) ATE326218T1 (enExample)
AU (1) AU2003238397A1 (enExample)
CA (1) CA2488220C (enExample)
DE (2) DE10224108A1 (enExample)
DK (1) DK1507519T3 (enExample)
ES (1) ES2263976T3 (enExample)
MY (1) MY134311A (enExample)
PE (1) PE20040529A1 (enExample)
PL (1) PL218397B1 (enExample)
PT (1) PT1507519E (enExample)
WO (1) WO2003099267A1 (enExample)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US5582837A (en) * 1992-03-25 1996-12-10 Depomed, Inc. Alkyl-substituted cellulose-based sustained-release oral drug dosage forms
JPH06172161A (ja) * 1992-12-10 1994-06-21 Shin Etsu Chem Co Ltd 徐放性錠剤
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
JPH1017497A (ja) * 1996-07-02 1998-01-20 Takeda Chem Ind Ltd 徐放性製剤およびその製造方法
DE10059412A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz

Also Published As

Publication number Publication date
JP2005534640A (ja) 2005-11-17
AR039900A1 (es) 2005-03-09
DE10224108A1 (de) 2004-01-29
DE50303372D1 (de) 2006-06-22
CA2488220A1 (en) 2003-12-04
MY134311A (en) 2007-12-31
AU2003238397A1 (en) 2003-12-12
PT1507519E (pt) 2006-08-31
DK1507519T3 (da) 2006-08-28
ATE326218T1 (de) 2006-06-15
EP1507519B1 (de) 2006-05-17
ES2263976T3 (es) 2006-12-16
PE20040529A1 (es) 2004-08-24
EP1507519A1 (de) 2005-02-23
PL218397B1 (pl) 2014-11-28
PL374186A1 (en) 2005-10-03
JP5459818B2 (ja) 2014-04-02
WO2003099267A1 (de) 2003-12-04

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20160526