CA2487291A1 - Human prolactin antagonist-angiogenesis inhibitor fusion proteins - Google Patents
Human prolactin antagonist-angiogenesis inhibitor fusion proteins Download PDFInfo
- Publication number
- CA2487291A1 CA2487291A1 CA002487291A CA2487291A CA2487291A1 CA 2487291 A1 CA2487291 A1 CA 2487291A1 CA 002487291 A CA002487291 A CA 002487291A CA 2487291 A CA2487291 A CA 2487291A CA 2487291 A1 CA2487291 A1 CA 2487291A1
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- domain
- protein
- endostatin
- prolactin
- receptor
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57554—Prolactin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38412102P | 2002-05-31 | 2002-05-31 | |
| US60/384,121 | 2002-05-31 | ||
| PCT/US2003/017216 WO2003102148A2 (en) | 2002-05-31 | 2003-06-02 | Human prolactin antagonist-angiogenesis inhibitor fusion proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2487291A1 true CA2487291A1 (en) | 2003-12-11 |
Family
ID=29711980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002487291A Abandoned CA2487291A1 (en) | 2002-05-31 | 2003-06-02 | Human prolactin antagonist-angiogenesis inhibitor fusion proteins |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7339027B2 (https=) |
| EP (1) | EP1513549A4 (https=) |
| JP (2) | JP4511108B2 (https=) |
| AU (1) | AU2003240974A1 (https=) |
| CA (1) | CA2487291A1 (https=) |
| WO (1) | WO2003102148A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2509825A1 (en) * | 2002-12-13 | 2004-07-01 | The Ohio State University | Antagonists for human prolactin |
| AU2011213758B2 (en) * | 2004-02-19 | 2012-11-15 | Yale University | Identification of cancer protein biomarkers using proteomic techniques |
| US7666583B2 (en) * | 2004-02-19 | 2010-02-23 | Yale University | Identification of cancer protein biomarkers using proteomic techniques |
| US7507716B2 (en) * | 2005-07-06 | 2009-03-24 | Board Of Regents, The University Of Texas System | Method for treating pain with prolactin antagonists |
| CA2635588C (en) | 2005-12-30 | 2015-11-10 | Dyax Corp. | Metalloproteinase binding proteins |
| WO2009135056A2 (en) * | 2008-04-30 | 2009-11-05 | Monsanto Technology Llc | Recombinant dna vectors for expression of human prolactin antagonists |
| JP6336389B2 (ja) | 2011-09-09 | 2018-06-06 | チンファ ユニヴァーシティＴｓｉｎｇｈｕａ Ｕｎｉｖｅｒｓｉｔｙ | Ａｔｐ結合部位に変異を有するエンドスタチン変異体 |
| US10314909B2 (en) | 2011-10-21 | 2019-06-11 | Dyax Corp. | Combination therapy comprising an MMP-14 binding protein |
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| JP2813428B2 (ja) * | 1989-08-17 | 1998-10-22 | 三菱電機株式会社 | 電界効果トランジスタ及び該電界効果トランジスタを用いた液晶表示装置 |
| US5315129A (en) * | 1990-08-20 | 1994-05-24 | University Of Southern California | Organic optoelectronic devices and methods |
| TW222345B (en) * | 1992-02-25 | 1994-04-11 | Semicondustor Energy Res Co Ltd | Semiconductor and its manufacturing method |
| FR2719480B1 (fr) * | 1994-05-05 | 1996-07-26 | Agronomique Inst Nat Rech | Compositions pharmaceutiques destinées à prévenir et/ou traiter l'expression du comportement de couvaison chez les oiseaux et plus particulièrement chez la dinde et leurs procédés de préparation. |
| US6278127B1 (en) * | 1994-12-09 | 2001-08-21 | Agere Systems Guardian Corp. | Article comprising an organic thin film transistor adapted for biasing to form a N-type or a P-type transistor |
| US5854205A (en) * | 1995-10-23 | 1998-12-29 | The Children's Medical Center Corporation | Therapeutic antiangiogenic compositions and methods |
| WO1999016889A1 (en) * | 1997-10-01 | 1999-04-08 | G.D. Searle & Co. | Fusion proteins comprising an angiostatin moiety and their use in anti-tumor treatment |
| WO1999046371A2 (en) | 1998-03-11 | 1999-09-16 | Board Of Regents, The University Of Texas System | Induction of apoptotic or cytotoxic gene expression by adenoviral mediated gene codelivery |
| EP1179541B1 (en) * | 1999-04-28 | 2004-06-16 | Board Of Regents, The University Of Texas System | Compositions and methods for cancer treatment by selectively inhibiting VEGF |
| CN1432064A (zh) * | 2000-03-23 | 2003-07-23 | 格林维尔医院系统公司 | 双功能癌症治疗剂 |
| US6803211B2 (en) * | 2000-08-25 | 2004-10-12 | Pfizer Inc. | Methods and compositions for diagnosing and treating disorders involving angiogenesis |
| JP4841751B2 (ja) * | 2001-06-01 | 2011-12-21 | 株式会社半導体エネルギー研究所 | 有機半導体装置及びその作製方法 |
| JP4136482B2 (ja) * | 2002-06-20 | 2008-08-20 | キヤノン株式会社 | 有機半導体素子、その製造方法および有機半導体装置 |
| EP1684365A3 (en) * | 2005-01-20 | 2008-08-13 | Fuji Electric Holdings Co., Ltd. | Transistor |
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2002
- 2002-10-25 JP JP2002311540A patent/JP4511108B2/ja not_active Expired - Fee Related
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2003
- 2003-06-02 EP EP03731479A patent/EP1513549A4/en not_active Withdrawn
- 2003-06-02 US US10/449,609 patent/US7339027B2/en not_active Expired - Lifetime
- 2003-06-02 WO PCT/US2003/017216 patent/WO2003102148A2/en not_active Ceased
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- 2003-06-02 CA CA002487291A patent/CA2487291A1/en not_active Abandoned
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2008
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2009
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|---|---|
| WO2003102148A2 (en) | 2003-12-11 |
| EP1513549A2 (en) | 2005-03-16 |
| JP2004002276A (ja) | 2004-01-08 |
| EP1513549A4 (en) | 2006-05-10 |
| AU2003240974A1 (en) | 2003-12-19 |
| US20090088375A1 (en) | 2009-04-02 |
| JP5221510B2 (ja) | 2013-06-26 |
| US7339027B2 (en) | 2008-03-04 |
| JP4511108B2 (ja) | 2010-07-28 |
| JP2010083896A (ja) | 2010-04-15 |
| US20040127407A1 (en) | 2004-07-01 |
| AU2003240974A8 (en) | 2003-12-19 |
| US8304381B2 (en) | 2012-11-06 |
| WO2003102148A3 (en) | 2004-07-29 |
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