CA2478904A1 - Modified gene-silencing rna and uses thereof - Google Patents
Modified gene-silencing rna and uses thereof Download PDFInfo
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- CA2478904A1 CA2478904A1 CA002478904A CA2478904A CA2478904A1 CA 2478904 A1 CA2478904 A1 CA 2478904A1 CA 002478904 A CA002478904 A CA 002478904A CA 2478904 A CA2478904 A CA 2478904A CA 2478904 A1 CA2478904 A1 CA 2478904A1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8249—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving ethylene biosynthesis, senescence or fruit development, e.g. modified tomato ripening, cut flower shelf-life
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/111—Antisense spanning the whole gene, or a large part of it
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| PL343064A1 (en) | 1998-03-20 | 2001-07-30 | Benitec Australia Ltd | Control of gene expression |
| JP2002542263A (ja) * | 1999-04-21 | 2002-12-10 | ワイス | ポリヌクレオチド配列の機能を阻害するための方法および組成物 |
| US7485715B2 (en) * | 1999-06-18 | 2009-02-03 | Ceres, Inc. | Sequence-determined DNA encoding AP2 domain polypeptides |
| US7479555B2 (en) * | 1999-07-21 | 2009-01-20 | Ceres, Inc. | Polynucleotides having a nucleotide sequence that encodes a polypeptide having MOV34 family activity |
| US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
| US7612194B2 (en) | 2001-07-24 | 2009-11-03 | Monsanto Technology Llc | Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof |
| ATE529512T1 (de) | 2002-02-01 | 2011-11-15 | Life Technologies Corp | Doppelsträngige oligonukleotide |
| WO2003064621A2 (en) | 2002-02-01 | 2003-08-07 | Ambion, Inc. | HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES |
| US20060009409A1 (en) | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
| US20050044590A1 (en) | 2003-08-15 | 2005-02-24 | Ruan Yong Ling | Methods and means for altering fiber characteristics in fiber-producing plants |
| WO2005026356A1 (en) * | 2003-09-12 | 2005-03-24 | Commonwealth Scientific And Industrial Research Organisation | Modified gene-silencing nucleic acid molecules and uses thereof |
| ATE526407T1 (de) * | 2003-11-17 | 2011-10-15 | Commw Scient Ind Res Org | Insektenresistenz durch inhibierung von genexpression |
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| MXPA06011694A (es) | 2004-04-09 | 2006-12-14 | Monsanto Technology Llc | Composiciones y metodos para el control de infestaciones de insectos en plantas. |
| EP1786917A4 (en) * | 2004-07-26 | 2008-05-28 | Enzon Pharmaceuticals Inc | OPTIMIZED INTERFERON BETA-GEN |
| BRPI0514342A2 (pt) | 2004-08-13 | 2009-10-06 | Basf Plant Science Gmbh | molécula de rna de filamento duplo, agrupamento de moléculas de rna de filamento duplo, planta transgênica, e, métodos para controlar a infecção de uma planta por um nematóide parasìtico e para fabricar uma planta transgênica |
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| WO2006070227A2 (en) * | 2004-10-04 | 2006-07-06 | Devgen Nv | Method for down-regulating gene expression in fungi |
| US7429692B2 (en) * | 2004-10-14 | 2008-09-30 | Ceres, Inc. | Sucrose synthase 3 promoter from rice and uses thereof |
| CA2584960A1 (en) | 2004-10-21 | 2006-05-04 | Charles L. Niblett | Methods and materials for conferring resistance to pests and pathogens of plants |
| BRPI0518249A2 (pt) | 2004-10-29 | 2008-11-11 | Bayer Bioscience Nv | plantas de algodço tolerantes À tensço |
| WO2008069878A2 (en) | 2006-10-27 | 2008-06-12 | Ceres, Inc. | Modulating lignin in plants |
| US9758790B2 (en) | 2004-12-08 | 2017-09-12 | Ceres, Inc. | Modulating the level of components within plants |
| US7335760B2 (en) * | 2004-12-22 | 2008-02-26 | Ceres, Inc. | Nucleic acid sequences encoding zinc finger proteins |
| US7795503B2 (en) * | 2005-02-22 | 2010-09-14 | Ceres, Inc. | Modulating plant alkaloids |
| ATE530656T1 (de) | 2005-02-23 | 2011-11-15 | Univ North Carolina State | Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene. |
| US20060236421A1 (en) * | 2005-04-14 | 2006-10-19 | Pennell Roger I | Secondary metabolite production via manipulation of genome methylation |
| US7312376B2 (en) * | 2005-04-20 | 2007-12-25 | Ceres, Inc. | Regulatory regions from Papaveraceae |
| US20060272057A1 (en) | 2005-05-25 | 2006-11-30 | Pioneer Hi-Bred International, Inc. | Methods for improving crop plant architecture and yield |
| US8124839B2 (en) * | 2005-06-08 | 2012-02-28 | Ceres, Inc. | Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations |
| EP3508582B1 (en) | 2005-09-16 | 2021-01-13 | Monsanto Technology LLC | Methods for genetic control of insect infestations in plants and compositions thereof |
| US20100062137A1 (en) * | 2005-09-30 | 2010-03-11 | Steven Craig Bobzin | Modulating plant tocopherol levels |
| US20090178160A1 (en) * | 2005-10-25 | 2009-07-09 | Joon-Hyun Park | Modulation of Triterpenoid Content in Plants |
| CN102174085A (zh) | 2005-11-10 | 2011-09-07 | 先锋高级育种国际公司 | Dof(具有一指的dna结合)序列和使用方法 |
| US20090304901A1 (en) * | 2006-01-25 | 2009-12-10 | Steven Craig Bobzin | Modulating plant protein levels |
| US8222482B2 (en) * | 2006-01-26 | 2012-07-17 | Ceres, Inc. | Modulating plant oil levels |
| CN101421295B (zh) | 2006-02-09 | 2012-05-02 | 先锋高级育种国际公司 | 用于提高作物植物中的氮利用效率的基因 |
| US20070199090A1 (en) * | 2006-02-22 | 2007-08-23 | Nestor Apuya | Modulating alkaloid biosynthesis |
| WO2007120989A2 (en) * | 2006-02-24 | 2007-10-25 | Ceres, Inc. | Shade regulatory regions |
| WO2007117693A2 (en) * | 2006-04-07 | 2007-10-18 | Ceres, Inc. | Regulatory protein-regulatory region associations related to alkaloid biosynthesis |
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| CN118995804B (zh) * | 2024-10-23 | 2025-02-28 | 青岛农业大学 | 一种突变型质粒及制备方法和应用 |
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| US4873191A (en) * | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US5190931A (en) * | 1983-10-20 | 1993-03-02 | The Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
| ATE198350T1 (de) | 1983-10-20 | 2001-01-15 | Univ New York State Res Found | Regulierung der genexpression durch translationshemmung unter verwendung einer m-rns behindernden komplementären rns |
| US6617496B1 (en) | 1985-10-16 | 2003-09-09 | Monsanto Company | Effecting virus resistance in plants through the use of negative strand RNAs |
| NZ219472A (en) | 1986-03-28 | 1990-08-28 | Calgene Inc | Regulation of phenotype in plant cells using dsdna constructs |
| US5037745A (en) * | 1986-04-01 | 1991-08-06 | University Of Medicine And Dentistry Of New Jersey | Plasmid for the overproduction of bacteriophage T3 RNA polymerase, transcription vectors that carry a promoter recognized by its polymerase, gene coding for T3 RNA polymerase and application of these plasmids |
| JP3026985B2 (ja) | 1987-10-20 | 2000-03-27 | プラント・ジェネティック・システムズ・エヌ・ブイ | 遺伝子導入植物内の修飾された貯蔵種子タンパク質遺伝子の発現による生物学的に活性なペプチドの製造方法 |
| GB8810120D0 (en) | 1988-04-28 | 1988-06-02 | Plant Genetic Systems Nv | Transgenic nuclear male sterile plants |
| WO1992013956A1 (en) | 1991-02-08 | 1992-08-20 | Plant Genetic Systems, N.V. | Stamen-specific promoters from rice |
| US5908779A (en) * | 1993-12-01 | 1999-06-01 | University Of Connecticut | Targeted RNA degradation using nuclear antisense RNA |
| NZ291734A (en) | 1994-08-30 | 1997-09-22 | Commw Scient Ind Res Org | Plant transcription regulators from circovirus; isolated nucleic acid molecules and transgenic plants |
| US6420628B1 (en) | 1995-10-06 | 2002-07-16 | Plant Genetic Systems, N.V. | Seed shattering |
| DE19631919C2 (de) | 1996-08-07 | 1998-07-16 | Deutsches Krebsforsch | Anti-Sinn-RNA mit Sekundärstruktur |
| WO2000049035A1 (en) * | 1999-02-19 | 2000-08-24 | The General Hospital Corporation | Gene silencing |
| US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
| HUP0302320A3 (en) | 2000-06-23 | 2005-11-28 | Pioneer Hi Bred Int | Recombinant constructs and their use in reducing gene expression |
| AU2001291656A1 (en) | 2000-06-30 | 2002-01-08 | Willem Broekaert | Gene silencing vector |
| US20020058340A1 (en) | 2000-08-02 | 2002-05-16 | Clemente Thomas E. | Down-regulation of single genes and simultaneous down-regulation of multiple genes by nuclear localization of RNA transcripts |
| CA2429397C (en) * | 2001-01-26 | 2014-06-03 | Commonwealth Scientific And Industrial Research Organisation | Methods and means for producing efficient silencing construct using recombinational cloning |
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2003
- 2003-03-12 EP EP03743758A patent/EP1487980A4/en not_active Withdrawn
- 2003-03-12 BR BR0308424-8A patent/BR0308424A/pt not_active Application Discontinuation
- 2003-03-12 JP JP2003574823A patent/JP2005519607A/ja active Pending
- 2003-03-12 CA CA002478904A patent/CA2478904A1/en not_active Abandoned
- 2003-03-12 WO PCT/AU2003/000292 patent/WO2003076619A1/en not_active Ceased
- 2003-03-12 AU AU2003209814A patent/AU2003209814B2/en not_active Ceased
- 2003-03-12 US US10/385,521 patent/US7576262B2/en not_active Expired - Fee Related
- 2003-03-12 CN CNA038082551A patent/CN1646687A/zh active Pending
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2004
- 2004-08-30 IN IN1268KO2004 patent/IN2004KO01268A/en unknown
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2008
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| WO2003076619A1 (en) | 2003-09-18 |
| BR0308424A (pt) | 2005-02-22 |
| JP2005519607A (ja) | 2005-07-07 |
| US7576262B2 (en) | 2009-08-18 |
| AU2003209814B2 (en) | 2008-12-04 |
| EP1487980A4 (en) | 2005-08-10 |
| US20090165153A1 (en) | 2009-06-25 |
| AU2003209814A1 (en) | 2003-09-22 |
| CN1646687A (zh) | 2005-07-27 |
| US20030180945A1 (en) | 2003-09-25 |
| EP1487980A1 (en) | 2004-12-22 |
| IN2004KO01268A (enExample) | 2006-05-05 |
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