CA2475526A1 - Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours - Google Patents

Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours Download PDF

Info

Publication number
CA2475526A1
CA2475526A1 CA002475526A CA2475526A CA2475526A1 CA 2475526 A1 CA2475526 A1 CA 2475526A1 CA 002475526 A CA002475526 A CA 002475526A CA 2475526 A CA2475526 A CA 2475526A CA 2475526 A1 CA2475526 A1 CA 2475526A1
Authority
CA
Canada
Prior art keywords
ptx3
derivative
tumour cells
sequence seq
tumour
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002475526A
Other languages
English (en)
French (fr)
Inventor
Rita De Santis
Giovanni Salvatori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2475526A1 publication Critical patent/CA2475526A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002475526A 2002-02-28 2003-02-25 Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours Abandoned CA2475526A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2002A000109 2002-02-28
IT2002RM000109A ITRM20020109A1 (it) 2002-02-28 2002-02-28 Derivati funzionali della pentraxina lunga ptx3 per preparare un vaccino autologo per la cura dei tumori.
PCT/IT2003/000104 WO2003072603A2 (en) 2002-02-28 2003-02-25 Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours

Publications (1)

Publication Number Publication Date
CA2475526A1 true CA2475526A1 (en) 2003-09-04

Family

ID=11456119

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002475526A Abandoned CA2475526A1 (en) 2002-02-28 2003-02-25 Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours

Country Status (12)

Country Link
US (1) US20090110666A1 (cg-RX-API-DMAC7.html)
EP (1) EP1478661A2 (cg-RX-API-DMAC7.html)
JP (1) JP2005538690A (cg-RX-API-DMAC7.html)
KR (1) KR20040099291A (cg-RX-API-DMAC7.html)
AR (1) AR038854A1 (cg-RX-API-DMAC7.html)
AU (1) AU2003214645A1 (cg-RX-API-DMAC7.html)
CA (1) CA2475526A1 (cg-RX-API-DMAC7.html)
IT (1) ITRM20020109A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA04008217A (cg-RX-API-DMAC7.html)
PL (1) PL372719A1 (cg-RX-API-DMAC7.html)
TW (1) TWI293958B (cg-RX-API-DMAC7.html)
WO (1) WO2003072603A2 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20040858A1 (it) 2004-04-29 2004-07-29 Farma Dev S R L Anticorpi monoclonali ibridomi metodo migliorato per determinare la proteina ptx3 e kit per detta determinazione
ITRM20040489A1 (it) 2004-10-08 2005-01-08 Sigma Tau Ind Farmaceuti Pentraxina lunga ptx3 deglicosilata o desialidata.
JP5427415B2 (ja) * 2006-01-24 2014-02-26 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ Ｆｇｆ２結合性ペプチドおよびそれらの使用
US8435525B1 (en) * 2010-04-16 2013-05-07 Andrew B. Bush FGF modulation of in vivo antibody production and humoral immunity
US9226960B2 (en) * 2010-04-16 2016-01-05 Andrew B. Bush FGF modulation of in vivo antibody production and humoral immunity
TWI531375B (zh) 2015-05-29 2016-05-01 國立成功大學 抑制癌細胞活性之短肽治療劑及含此之醫藥組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849478A (en) * 1986-08-14 1998-12-15 Cashman; Daniel P. Blocked-polymerase polynucleotide immunoassay method and kit
US5290551A (en) * 1990-05-08 1994-03-01 Thomas Jefferson University Treatment of melanoma with a vaccine comprising irradiated autologous melanoma tumor cells conjugated to a hapten
IT1298487B1 (it) * 1997-12-19 2000-01-10 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
IT1317927B1 (it) * 2000-11-03 2003-07-15 Sigma Tau Ind Farmaceuti Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni.
IT1317930B1 (it) * 2000-11-08 2003-07-15 Sigma Tau Ind Farmaceuti Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patalogie associate ad una alterata attivazione
US20020122820A1 (en) * 2001-01-16 2002-09-05 Hildebrand William H. Soluble MHC artificial antigen presenting cells
US7041648B2 (en) * 2001-08-03 2006-05-09 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Compositions and methods for treating female fertility
ES2261714T3 (es) * 2001-08-03 2006-11-16 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Uso de la pentraxina larga ptx3 para tratar la infertilidad femenina.
ITRM20020191A1 (it) * 2002-04-08 2003-10-08 Sigma Tau Ind Farmaceuti Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie tumorali associate ad una alterata att
US20040137544A1 (en) * 2002-10-31 2004-07-15 Roberto Latini PTX3 as an early prognostic indicator of cardiovascular and cerebrovascular pathologies
ITRM20030596A1 (it) * 2003-12-23 2005-06-24 Sigma Tau Ind Farmaceuti Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3.
US20070023879A1 (en) * 2005-07-29 2007-02-01 Vinayak Pandey Single unit heat sink, voltage regulator, and package solution for an integrated circuit

Also Published As

Publication number Publication date
TW200303755A (en) 2003-09-16
WO2003072603A2 (en) 2003-09-04
ITRM20020109A1 (it) 2003-08-28
TWI293958B (en) 2008-03-01
US20090110666A1 (en) 2009-04-30
MXPA04008217A (es) 2004-11-26
AU2003214645A1 (en) 2003-09-09
AU2003214645A8 (en) 2003-09-09
PL372719A1 (en) 2005-07-25
WO2003072603A3 (en) 2004-03-18
EP1478661A2 (en) 2004-11-24
WO2003072603A9 (en) 2004-10-07
AR038854A1 (es) 2005-01-26
KR20040099291A (ko) 2004-11-26
JP2005538690A (ja) 2005-12-22
ITRM20020109A0 (it) 2002-02-28

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued