CA2445381C - Phosphorous antimicrobial compounds and methods for their use - Google Patents

Phosphorous antimicrobial compounds and methods for their use Download PDF

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Publication number
CA2445381C
CA2445381C CA2445381A CA2445381A CA2445381C CA 2445381 C CA2445381 C CA 2445381C CA 2445381 A CA2445381 A CA 2445381A CA 2445381 A CA2445381 A CA 2445381A CA 2445381 C CA2445381 C CA 2445381C
Authority
CA
Canada
Prior art keywords
compound
group
compounds
protonated
antimicrobial composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2445381A
Other languages
English (en)
French (fr)
Other versions
CA2445381A1 (en
Inventor
Roderic M. K. Dale
Steven L. Gatton
Amy Arrow
Terry Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lakewood-Amedex Inc
Original Assignee
Lakewood-Amedex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lakewood-Amedex Inc filed Critical Lakewood-Amedex Inc
Priority to CA2827671A priority Critical patent/CA2827671C/en
Publication of CA2445381A1 publication Critical patent/CA2445381A1/en
Application granted granted Critical
Publication of CA2445381C publication Critical patent/CA2445381C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
CA2445381A 2001-05-03 2002-05-03 Phosphorous antimicrobial compounds and methods for their use Expired - Fee Related CA2445381C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2827671A CA2827671C (en) 2001-05-03 2002-05-03 Phosphorus-containing antimicrobial compounds and methods for their use

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/847,654 2001-05-03
US09/847,654 US20020032164A1 (en) 1998-12-30 2001-05-03 Antimicrobial compounds and methods for their use
PCT/US2002/013910 WO2002089581A1 (en) 2001-05-03 2002-05-03 Antimicrobial compounds and methods for their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2827671A Division CA2827671C (en) 2001-05-03 2002-05-03 Phosphorus-containing antimicrobial compounds and methods for their use

Publications (2)

Publication Number Publication Date
CA2445381A1 CA2445381A1 (en) 2002-11-14
CA2445381C true CA2445381C (en) 2013-09-17

Family

ID=25301163

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2445381A Expired - Fee Related CA2445381C (en) 2001-05-03 2002-05-03 Phosphorous antimicrobial compounds and methods for their use
CA2827671A Expired - Fee Related CA2827671C (en) 2001-05-03 2002-05-03 Phosphorus-containing antimicrobial compounds and methods for their use

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2827671A Expired - Fee Related CA2827671C (en) 2001-05-03 2002-05-03 Phosphorus-containing antimicrobial compounds and methods for their use

Country Status (10)

Country Link
US (2) US20020032164A1 (enExample)
EP (2) EP1389909B1 (enExample)
JP (4) JP4347573B2 (enExample)
AU (1) AU2002305336B2 (enExample)
CA (2) CA2445381C (enExample)
CY (1) CY1116784T1 (enExample)
DK (1) DK2311466T3 (enExample)
ES (1) ES2549766T3 (enExample)
PT (1) PT2311466E (enExample)
WO (1) WO2002089581A1 (enExample)

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CA2549017A1 (en) * 2003-08-01 2005-02-10 Mona Patel Substituted indazole-o-glucosides
CN104109155A (zh) 2003-08-01 2014-10-22 田边三菱制药株式会社 新颖化合物
US8785403B2 (en) 2003-08-01 2014-07-22 Mitsubishi Tanabe Pharma Corporation Glucopyranoside compound
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UY30730A1 (es) * 2006-12-04 2008-07-03 Mitsubishi Tanabe Pharma Corp Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
WO2008135085A1 (en) * 2007-05-04 2008-11-13 Symrise Gmbh & Co. Kg Synergistic active preparations comprising 1,2-decanediol and further antimicrobial active compounds
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GB2460445B (en) * 2008-05-30 2012-07-11 Vernolix Ltd Treatment of ringworm
US9056850B2 (en) * 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
JP5658751B2 (ja) 2009-07-10 2015-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ １−（β−Ｄ−グルコピラノシル）−４−メチル−３−［５−（４−フルオロフェニル）−２−チエニルメチル］ベンゼンのための結晶化方法
WO2011047113A1 (en) * 2009-10-14 2011-04-21 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
NZ703128A (en) 2010-05-11 2016-04-29 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
WO2012140120A1 (en) 2011-04-13 2012-10-18 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
TWI542596B (zh) 2011-05-09 2016-07-21 健生藥品公司 （２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
KR102684529B1 (ko) 2017-03-10 2024-07-12 레이크우드 아메덱스, 인크. 항미생물 화합물, 조성물, 및 그의 용도
US12030908B2 (en) 2017-03-10 2024-07-09 Lakewood Amedex, Inc. Antimicrobial compounds, compositions, and uses thereof
US11795192B2 (en) 2017-03-10 2023-10-24 Lakewood Amedex, Inc. Antimicrobial compounds, compositions, and uses thereof
US11377468B2 (en) 2017-03-10 2022-07-05 Lakewood Amedex, Inc. Antimicrobial compounds, compositions, and uses thereof
KR20260035292A (ko) 2017-06-12 2026-03-12 레이크우드 아메덱스, 인크. 비스포스포신 겔 제제 및 이의 용도
EP3641725A1 (en) 2017-06-23 2020-04-29 The Procter and Gamble Company Composition and method for improving the appearance of skin
US11622963B2 (en) 2018-07-03 2023-04-11 The Procter & Gamble Company Method of treating a skin condition
CN112839662A (zh) 2018-10-17 2021-05-25 莱克伍德阿美达克斯股份有限公司 用于治疗口腔粘膜炎的方法和组合物
CZ308943B6 (cs) * 2019-12-12 2021-09-22 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipofosfonoxiny třetí generace, jejich příprava a použití
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
CN115843238B (zh) 2020-06-01 2025-06-10 宝洁公司 改善维生素b3化合物渗透到皮肤中的方法
KR20220009630A (ko) * 2020-07-16 2022-01-25 정준영 플라즈마를 이용한 마스크 폐기 처리기
CN115448967A (zh) * 2022-09-26 2022-12-09 泽同医药科技(南通)有限公司 一种吩噁嗪半乳烯糖碳苷化合物及其合成方法
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Also Published As

Publication number Publication date
AU2002305336B2 (en) 2007-11-08
US7176191B2 (en) 2007-02-13
EP1389909A4 (en) 2005-03-30
CY1116784T1 (el) 2017-03-15
JP4347573B2 (ja) 2009-10-21
DK2311466T3 (en) 2015-10-19
EP2311466A3 (en) 2012-04-25
JP2009179639A (ja) 2009-08-13
JP2005511482A (ja) 2005-04-28
JP2014055139A (ja) 2014-03-27
PT2311466E (pt) 2015-10-27
EP1389909A1 (en) 2004-02-25
ES2549766T3 (es) 2015-11-02
JP2016056177A (ja) 2016-04-21
JP6097372B2 (ja) 2017-03-15
US20050107344A1 (en) 2005-05-19
CA2827671A1 (en) 2002-11-14
CA2827671C (en) 2016-07-05
WO2002089581A1 (en) 2002-11-14
US20020032164A1 (en) 2002-03-14
CA2445381A1 (en) 2002-11-14
EP1389909B1 (en) 2012-07-18
JP5503900B2 (ja) 2014-05-28
EP2311466A2 (en) 2011-04-20
JP5883838B2 (ja) 2016-03-15
EP2311466B1 (en) 2015-07-08

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