CA2430292A1 - Souche bacterienne, extraits de plantes traites, compositions a base de ces elements, procedes relatifs a leur elaboration, et leurs applications therapeutiques et industrielles - Google Patents
Souche bacterienne, extraits de plantes traites, compositions a base de ces elements, procedes relatifs a leur elaboration, et leurs applications therapeutiques et industrielles Download PDFInfo
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- CA2430292A1 CA2430292A1 CA002430292A CA2430292A CA2430292A1 CA 2430292 A1 CA2430292 A1 CA 2430292A1 CA 002430292 A CA002430292 A CA 002430292A CA 2430292 A CA2430292 A CA 2430292A CA 2430292 A1 CA2430292 A1 CA 2430292A1
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- microorganism
- probiotic composition
- volatile fraction
- plant extract
- probiotic
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Applications Claiming Priority (3)
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| US09/725,846 | 2000-11-30 | ||
| US09/725,846 US6500423B2 (en) | 1999-06-03 | 2000-11-30 | Bacterial strain, processed plant extracts, compositions containing same, processes for their preparation and their therapeutic and industrial applications |
| PCT/IL2001/001088 WO2002043649A2 (fr) | 2000-11-30 | 2001-11-27 | Souche bacterienne, extraits de plantes traites, compositions a base de ces elements, procedes relatifs a leur elaboration, et leurs applications therapeutiques et industrielles |
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| CA2430292A1 true CA2430292A1 (fr) | 2002-06-06 |
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| US20050042207A1 (en) * | 2003-08-18 | 2005-02-24 | The Bio Balance Corporation | Stable liquid probiotic composition, preparation and applications thereof |
| MY143693A (en) | 2004-03-24 | 2011-06-30 | Nestec Sa | Shelf stable product wih living micro-organisms |
| JP2009537547A (ja) * | 2006-05-18 | 2009-10-29 | バイオバランス エルエルシー | 生物学的治療組成物およびその使用 |
| RU2453320C2 (ru) * | 2008-08-05 | 2012-06-20 | Виктор Владимирович Чалов | Композиция для перорального применения, содержащая непатогенные микроорганизмы, обладающая способностью нормализовать микрофлору кишечника (варианты) |
| KR101127171B1 (ko) * | 2009-07-24 | 2012-03-20 | (주)애드바이오텍 | 오리의 급만성 전염질병을 유발하는 병원체에 대한 항체를 지닌 난황을 함유하는 오리 사료 첨가용 조성물 |
| US20120183960A1 (en) | 2010-12-07 | 2012-07-19 | Enterologics, Inc. | Method for identifying e. coli m-17 |
| RU2458527C1 (ru) * | 2010-12-30 | 2012-08-20 | Общество с ограниченной ответственностью "БИОТРОФ" | Способ получения препарата для кормления сельскохозяйственных животных и птицы и способ приготовления корма на его основе |
| JP6278960B2 (ja) * | 2012-07-20 | 2018-02-14 | プレヴテック マイクロビア インコーポレイテッド | 非病原性ｆ１８ｅ．ｃｏｌｉ株及びその使用 |
| JP6452607B2 (ja) | 2012-09-25 | 2019-01-16 | アキロン セイエレ エセ．エレ． | プロバイオティクス組成物及びプレバイオティクス組成物 |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| NZ709392A (en) * | 2012-11-23 | 2016-10-28 | Seres Therapeutics Inc | Synergistic bacterial compositions and methods of production and use thereof |
| BR112015018625A2 (pt) | 2013-02-04 | 2017-09-19 | Seres Therapeutics Inc | composições e métodos |
| EP3904502A3 (fr) | 2013-02-04 | 2022-02-23 | Seres Therapeutics, Inc. | Compositions et procédés |
| US9717726B2 (en) | 2013-03-14 | 2017-08-01 | Maregade Rx, LLC | Product and method for treating diarrhea |
| AU2014232370B2 (en) | 2013-03-15 | 2018-11-01 | Seres Therapeutics, Inc. | Network-based microbial compositions and methods |
| BR112016011830A2 (pt) | 2013-11-25 | 2017-09-26 | Seres Therapeutics Inc | composições bacterianas sinergísticas e métodos para produção e uso das mesmas. |
| WO2015095241A2 (fr) | 2013-12-16 | 2015-06-25 | Seres Health, Inc. | Compositions bactériennes et leurs méthodes d'utilisation pour traiter des troubles du système immunitaire |
| RU2660355C2 (ru) * | 2016-04-01 | 2018-07-05 | Акционерное общество "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" | Антибактериальная фармацевтическая композиция для перорального применения, содержащая бактериофаги |
| WO2017214727A1 (fr) * | 2016-06-14 | 2017-12-21 | Prevtec Microbia Inc. | Granules d'alimentaire pour animaux comprenant un additif alimentaire, procédé pour les fabriquer et les utiliser |
| RU2639544C1 (ru) * | 2016-12-16 | 2017-12-21 | Общество с ограниченной ответственностью "БИОРЕАКТОР" | Средство для лечения и профилактики заболеваний желудочно-кишечного тракта птицы |
| ES2953520T3 (es) | 2016-12-23 | 2023-11-14 | Maregade Rx Llc | Producto a baja dosis y método para el tratamiento de la diarrea |
| CN107319103A (zh) * | 2017-08-01 | 2017-11-07 | 河南牧业经济学院 | 促进畜禽生长和肠道发育的饲料添加剂及其制备方法和应用 |
| BR112020002992A2 (pt) | 2017-08-14 | 2020-08-18 | Seres Therapeutics, Inc. | composições e métodos para tratamento de doença colestática |
| KR101939080B1 (ko) * | 2017-10-23 | 2019-01-16 | 고려대학교 산학협력단 | 슈도모나스 베로니 균주 kacc 81051bp 및 이를 포함하는 조성물 |
| CN109260235A (zh) * | 2018-10-23 | 2019-01-25 | 上海市第十人民医院 | 一种组合物在制备防治便秘药物或保健品中的应用 |
| CN110004072B (zh) * | 2018-11-12 | 2021-08-13 | 西安交通大学 | 一株益生性粪肠球菌分离株a3-1及其应用 |
| CN113652340A (zh) * | 2021-08-24 | 2021-11-16 | 江苏江大源生态生物科技股份有限公司 | 一种益生菌制剂、菌种筛选装置及筛选方法 |
| CN113616715B (zh) * | 2021-08-31 | 2022-05-06 | 昆明理工大学 | 治疗仔猪腹泻及改善其肠道菌群的发酵中药口服液 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3908028A (en) * | 1973-04-19 | 1975-09-23 | Procter & Gamble | Soft drink composition containing paramethoxycinnamaldehyde as a flavoring agent and sweetner |
| GB1501098A (en) * | 1974-06-11 | 1978-02-15 | Brewing Patents Ltd | Preparation of hop oil |
| US4986985A (en) * | 1987-11-02 | 1991-01-22 | Bar Ilan University | Method of treating skin virus infections |
| CH675685A5 (fr) * | 1988-06-24 | 1990-10-31 | Flachsmann Ag Emil | |
| US5443826A (en) * | 1988-08-02 | 1995-08-22 | Borody; Thomas J. | Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli |
| US5082489A (en) * | 1990-02-06 | 1992-01-21 | The Royal Institution For The Advancement Of Learning (Mcgill University) | Composition for biocontrol of wild buckwheat |
| US5478557A (en) * | 1992-07-29 | 1995-12-26 | The United States Of America, As Represented By The Secretary Of Agriculture | Probiotic for control of salmonella |
| US5486367A (en) * | 1992-10-13 | 1996-01-23 | Kansas State University Research Foundation | Enzymatic method for accelerating fermentation of comestible products |
| US5376374A (en) * | 1993-05-24 | 1994-12-27 | Zelaya; Luz M. | Oral rinse composition |
| US5733774A (en) * | 1995-02-02 | 1998-03-31 | Ecoscience Corporation | Method and composition for producing stable bacteria and bacterial formulations |
| AU714310B2 (en) * | 1995-05-12 | 1999-12-23 | Japan Pharmaceutical Development Co., Ltd | Plant extract |
| ES2167575T3 (es) * | 1995-05-26 | 2002-05-16 | D & W Trading B V | Composiciones farmaceuticas basadas en aceites etericos obtenidos a partir de plantas, para uso en el campo de la medicina humana. |
| US5679364A (en) * | 1995-06-07 | 1997-10-21 | Lee County Mosquito Control District | Compositions and methods for reducing the amount of contaminants in aquatic and terrestrial environments |
| GB2303799B (en) * | 1995-07-29 | 1999-03-10 | Siemens Plc | Improvements in or relating to aqueous sample testing apparatus |
| US5888395A (en) * | 1996-08-30 | 1999-03-30 | The Regents Of The University Of California | Method for enhanced longevity of in situ microbial filter used for bioremediation |
| US5773075A (en) * | 1996-12-13 | 1998-06-30 | Kalamazoo Holdings, Inc. | High temperature countercurrent solvent extraction of Capsicum solids |
| US5965128A (en) * | 1997-08-13 | 1999-10-12 | University Of Georgia Research Foundation Inc. | Control of enterohemorrhagic E. coli 0157:H7 in cattle by probiotic bacteria and specific strains of E. coli |
| IL130303A0 (en) * | 1999-06-03 | 2000-06-01 | M G Novobiotech Ltd | A bacterial strain processed plant extracts and probiotic compositions for human and veterinary use |
-
2001
- 2001-11-27 CA CA002430292A patent/CA2430292A1/fr not_active Abandoned
- 2001-11-27 RU RU2003119151/13A patent/RU2281326C2/ru not_active IP Right Cessation
- 2001-11-27 NZ NZ526748A patent/NZ526748A/xx unknown
- 2001-11-27 BR BR0116178-4A patent/BR0116178A/pt not_active IP Right Cessation
- 2001-11-27 AU AU2100402A patent/AU2100402A/xx active Pending
- 2001-11-27 JP JP2002545628A patent/JP4410992B2/ja not_active Expired - Fee Related
- 2001-11-27 EP EP01998302A patent/EP1343370A4/fr not_active Ceased
- 2001-11-27 CN CNB018214851A patent/CN1294253C/zh not_active Expired - Fee Related
- 2001-11-27 AU AU2002221004A patent/AU2002221004B2/en not_active Ceased
- 2001-11-27 IL IL15621301A patent/IL156213A0/xx unknown
- 2001-11-27 WO PCT/IL2001/001088 patent/WO2002043649A2/fr active Application Filing
- 2001-11-27 MX MXPA03004851A patent/MXPA03004851A/es not_active Application Discontinuation
- 2001-11-27 PL PL01366363A patent/PL366363A1/xx unknown
- 2001-11-27 KR KR10-2003-7007337A patent/KR20030082549A/ko not_active Application Discontinuation
-
2003
- 2003-06-19 ZA ZA200304747A patent/ZA200304747B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03004851A (es) | 2004-05-04 |
| JP2004534512A (ja) | 2004-11-18 |
| WO2002043649A2 (fr) | 2002-06-06 |
| AU2002221004B2 (en) | 2007-01-25 |
| WO2002043649A8 (fr) | 2004-04-29 |
| CN1494374A (zh) | 2004-05-05 |
| IL156213A0 (en) | 2003-12-23 |
| AU2100402A (en) | 2002-06-11 |
| WO2002043649A3 (fr) | 2002-08-29 |
| RU2281326C2 (ru) | 2006-08-10 |
| BR0116178A (pt) | 2003-10-14 |
| EP1343370A4 (fr) | 2004-02-11 |
| JP4410992B2 (ja) | 2010-02-10 |
| CN1294253C (zh) | 2007-01-10 |
| NZ526748A (en) | 2006-03-31 |
| ZA200304747B (en) | 2004-09-03 |
| EP1343370A2 (fr) | 2003-09-17 |
| PL366363A1 (en) | 2005-01-24 |
| KR20030082549A (ko) | 2003-10-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20121127 |