CA2429681A1 - Device and method for the controlled heating in micro channel systems - Google Patents

Device and method for the controlled heating in micro channel systems Download PDF

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Publication number
CA2429681A1
CA2429681A1 CA002429681A CA2429681A CA2429681A1 CA 2429681 A1 CA2429681 A1 CA 2429681A1 CA 002429681 A CA002429681 A CA 002429681A CA 2429681 A CA2429681 A CA 2429681A CA 2429681 A1 CA2429681 A1 CA 2429681A1
Authority
CA
Canada
Prior art keywords
substrate
heating
disc
selected area
reactor system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002429681A
Other languages
English (en)
French (fr)
Inventor
Gunnar Kylberg
Owe Salven
Per Andersson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gyros Patent AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2429681A1 publication Critical patent/CA2429681A1/en
Abandoned legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • B01L2300/0806Standardised forms, e.g. compact disc [CD] format
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • B01L2300/1844Means for temperature control using fluid heat transfer medium using fans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1861Means for temperature control using radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • General Preparation And Processing Of Foods (AREA)
CA002429681A 2000-11-23 2001-11-23 Device and method for the controlled heating in micro channel systems Abandoned CA2429681A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0004296A SE0004296D0 (sv) 2000-11-23 2000-11-23 Device and method for the controlled heating in micro channel systems
SE0004296-0 2000-11-23
PCT/SE2001/002607 WO2002041997A1 (en) 2000-11-23 2001-11-23 Device and method for the controlled heating in micro channel systems

Publications (1)

Publication Number Publication Date
CA2429681A1 true CA2429681A1 (en) 2002-05-30

Family

ID=20281936

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002429681A Abandoned CA2429681A1 (en) 2000-11-23 2001-11-23 Device and method for the controlled heating in micro channel systems

Country Status (9)

Country Link
US (2) US6985672B2 (ja)
EP (1) EP1349658B1 (ja)
JP (1) JP4533581B2 (ja)
AT (1) ATE456398T1 (ja)
AU (1) AU2002223167A1 (ja)
CA (1) CA2429681A1 (ja)
DE (1) DE60141223D1 (ja)
SE (1) SE0004296D0 (ja)
WO (1) WO2002041997A1 (ja)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808836D0 (en) * 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
SE9902474D0 (sv) 1999-06-30 1999-06-30 Amersham Pharm Biotech Ab Polymer valves
SE9904802D0 (sv) * 1999-12-23 1999-12-23 Amersham Pharm Biotech Ab Microfluidic surfaces
SE0004296D0 (sv) * 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
JP4323806B2 (ja) 2001-03-19 2009-09-02 ユィロス・パテント・アクチボラグ 反応可変要素の特徴付け
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US20040132166A1 (en) * 2001-04-10 2004-07-08 Bioprocessors Corp. Determination and/or control of reactor environmental conditions
US7440684B2 (en) * 2001-04-12 2008-10-21 Spaid Michael A Method and apparatus for improved temperature control in microfluidic devices
EP2281633A1 (en) 2001-08-28 2011-02-09 Gyros Patent Ab Retaining microfluidic microcavity and other microfluidic structures
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
DE60237289D1 (de) 2001-09-17 2010-09-23 Gyros Patent Ab Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
US20050026134A1 (en) * 2002-04-10 2005-02-03 Bioprocessors Corp. Systems and methods for control of pH and other reactor environment conditions
US7041258B2 (en) * 2002-07-26 2006-05-09 Applera Corporation Micro-channel design features that facilitate centripetal fluid transfer
JP4519124B2 (ja) * 2003-01-30 2010-08-04 ユィロス・パテント・アクチボラグ 微小流動性デバイスの内部の壁
SE0300822D0 (sv) * 2003-03-23 2003-03-23 Gyros Ab A collection of Micro Scale Devices
SE0300823D0 (sv) 2003-03-23 2003-03-23 Gyros Ab Preloaded Microscale Devices
JP2007502218A (ja) 2003-05-23 2007-02-08 ユィロス・パテント・アクチボラグ 親水性/疎水性表面
US20060246526A1 (en) * 2003-06-02 2006-11-02 Gyros Patent Ab Microfluidic affinity assays with improved performance
EP2402089A1 (en) 2003-07-31 2012-01-04 Handylab, Inc. Processing particle-containing samples
US20060210426A1 (en) * 2003-08-05 2006-09-21 Taiyo Yuden Co., Ltd. Sample analyzer and disk-like sample analyzing medium
US7329391B2 (en) 2003-12-08 2008-02-12 Applera Corporation Microfluidic device and material manipulating method using same
SE0400007D0 (sv) * 2004-01-02 2004-01-02 Gyros Ab Large scale surface modifiv´cation of microfluidic devices
WO2005065827A1 (en) * 2004-01-06 2005-07-21 Gyros Patent Ab Contact heating arrangement
SE0400181D0 (sv) * 2004-01-29 2004-01-29 Gyros Ab Segmented porous and preloaded microscale devices
DE102004017750B4 (de) * 2004-04-06 2006-03-16 Flechsig, Gerd-Uwe, Dr. rer. nat. Analyse-Array mit heizbaren Elektroden
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
US7709249B2 (en) * 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
JP2006329716A (ja) * 2005-05-24 2006-12-07 Ushio Inc マイクロチップ測定装置
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
US7527763B2 (en) 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US20070134739A1 (en) * 2005-12-12 2007-06-14 Gyros Patent Ab Microfluidic assays and microfluidic devices
JP2007209910A (ja) * 2006-02-10 2007-08-23 Aloka Co Ltd マイクロチップおよび反応処理装置
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
EP2001990B1 (en) 2006-03-24 2016-06-29 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using same
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7629124B2 (en) * 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
EP2091647A2 (en) 2006-11-14 2009-08-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US20080152543A1 (en) * 2006-11-22 2008-06-26 Hideyuki Karaki Temperature regulation method of microfluidic chip, sample analysis system and microfluidic chip
WO2008139415A1 (en) * 2007-05-14 2008-11-20 Koninklijke Philips Electronics N.V. Microfluidic device and method of operating a microfluidic device
EP2465609B1 (en) 2007-06-21 2016-12-28 Gen-Probe Incorporated Method for mixing the contents of a detection chamber
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
EP3741869A1 (en) 2007-07-13 2020-11-25 Handylab, Inc. Polynucleotide capture materials and methods of using same
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US9121055B2 (en) * 2008-04-24 2015-09-01 3M Innovative Properties Company Analysis of nucleic acid amplification curves using wavelet transformation
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
FR2950359B1 (fr) * 2009-09-23 2011-12-02 Univ Compiegne Tech Dispositif et systeme de filtration
CN103502593A (zh) * 2010-12-23 2014-01-08 英瑞杰汽车系统研究公司 发动机排气添加剂储存系统
CA3082652A1 (en) 2011-04-15 2012-10-18 Becton, Dickinson And Company Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
KR102121853B1 (ko) 2011-09-30 2020-06-12 벡톤 디킨슨 앤드 컴퍼니 일체화된 시약 스트립
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
EP2810080B1 (en) 2012-02-03 2024-03-27 Becton, Dickinson and Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
KR102312555B1 (ko) 2015-07-30 2021-10-14 더 리전트 오브 더 유니버시티 오브 캘리포니아 광 공동 pcr
DE102016208972A1 (de) 2016-05-24 2017-11-30 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Fluidikmodul, Vorrichtung und Verfahren zum biochemischen Prozessieren einer Flüssigkeit unter Verwendung von mehreren Temperaturzonen
DE102018212930B3 (de) * 2018-08-02 2019-11-07 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und Verfahren zum Leiten einer Flüssigkeit durch ein poröses Medium
CN113166021A (zh) 2018-10-16 2021-07-23 克里普托斯生物技术有限公司 用于通过照射图案化的薄膜进行局部加热的方法和系统
US11648563B2 (en) 2018-12-21 2023-05-16 Kryptos Biotechnologies, Inc. Method and system for heating and temperature measurement using patterned thin films

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5955344A (ja) * 1982-09-25 1984-03-30 Ushio Inc 薄膜の局部加熱方法
JPH01274422A (ja) * 1988-04-27 1989-11-02 Nec Corp 半導体基板の熱処理方法
JPH03248340A (ja) * 1990-02-27 1991-11-06 Fuji Xerox Co Ltd 光記録媒体とこれを用いた光学的記録方法
US5073698A (en) * 1990-03-23 1991-12-17 Peak Systems, Inc. Method for selectively heating a film on a substrate
SE470347B (sv) * 1990-05-10 1994-01-31 Pharmacia Lkb Biotech Mikrostruktur för vätskeflödessystem och förfarande för tillverkning av ett sådant system
SE508435C2 (sv) * 1993-02-23 1998-10-05 Erik Stemme Förträngningspump av membranpumptyp
SE501380C2 (sv) * 1993-06-15 1995-01-30 Pharmacia Lkb Biotech Sätt att tillverka mikrokanal/mikrokavitetsstrukturer
SE9304145D0 (sv) * 1993-12-10 1993-12-10 Pharmacia Lkb Biotech Sätt att tillverka hålrumsstrukturer
SE9401327D0 (sv) * 1994-04-20 1994-04-20 Pharmacia Lkb Biotech Hydrofilisering av hydrofob polymer
EP0823054A1 (en) * 1995-04-27 1998-02-11 Pharmacia Biotech AB Apparatus for continuously measuring physical and chemical parameters in a fluid flow
SE9502251D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Ab Flow-through sampling cell and use thereof
SE9502258D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Biotech Ab Method for the manufacture of a membrane-containing microstructure
US6113702A (en) * 1995-09-01 2000-09-05 Asm America, Inc. Wafer support system
US5705813A (en) * 1995-11-01 1998-01-06 Hewlett-Packard Company Integrated planar liquid handling system for maldi-TOF MS
KR100306951B1 (ko) * 1995-12-05 2001-11-15 테칸 보스턴, 인코포레이티드 내장된정보과학에의해미세유체공학시스템내의유체유동을구동시키기위해구심가속도를이용하는장치및방법
US6144447A (en) * 1996-04-25 2000-11-07 Pharmacia Biotech Ab Apparatus for continuously measuring physical and chemical parameters in a fluid flow
SE9602638D0 (sv) * 1996-07-03 1996-07-03 Pharmacia Biotech Ab An improved method for the capillary electrophoresis of nucleic acids, proteins and low molecular charged compounds
US6063589A (en) 1997-05-23 2000-05-16 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement on a microfluidics system
EP1003759A2 (en) * 1997-08-13 2000-05-31 Cepheid Microstructures for the manipulation of fluid samples
US5989402A (en) * 1997-08-29 1999-11-23 Caliper Technologies Corp. Controller/detector interfaces for microfluidic systems
GB9808836D0 (en) * 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
US20040202579A1 (en) * 1998-05-08 2004-10-14 Anders Larsson Microfluidic device
GB9809943D0 (en) 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
JP3817389B2 (ja) * 1998-06-11 2006-09-06 株式会社日立製作所 ポリヌクレオチド分取装置
US6454970B1 (en) * 1998-10-14 2002-09-24 Amic Ab And Gyros Ab Matrix, method of producing and using the matrix and machine including the matrix
SE9803734D0 (sv) 1998-10-30 1998-10-30 Amersham Pharm Biotech Ab Liquid handling system
US6261431B1 (en) 1998-12-28 2001-07-17 Affymetrix, Inc. Process for microfabrication of an integrated PCR-CE device and products produced by the same
SE0001779D0 (sv) 2000-05-12 2000-05-12 Gyros Ab Microanalysis device
US7261859B2 (en) 1998-12-30 2007-08-28 Gyros Ab Microanalysis device
SE9901100D0 (sv) 1999-03-24 1999-03-24 Amersham Pharm Biotech Ab Surface and tis manufacture and uses
SE9901306D0 (sv) 1999-04-09 1999-04-09 Amersham Pharm Biotech Ab Improved TIRF chamber
US6605475B1 (en) * 1999-04-16 2003-08-12 Perspective Biosystems, Inc. Apparatus and method for sample delivery
US6555389B1 (en) 1999-05-11 2003-04-29 Aclara Biosciences, Inc. Sample evaporative control
AU5887000A (en) 1999-06-22 2001-01-09 Tecan Trading Ag Devices and methods for the performance of miniaturized in vitro amplification assays
SE9902474D0 (sv) 1999-06-30 1999-06-30 Amersham Pharm Biotech Ab Polymer valves
JP3990910B2 (ja) * 1999-07-16 2007-10-17 アプレラ コーポレイション 高密度電気泳動デバイスおよび方法
SE9903011D0 (sv) * 1999-08-26 1999-08-26 Aamic Ab Sätt att framställa en plastprodukt och ett härför utnyttjat plastproduktformande arrangemang
GB2355717A (en) 1999-10-28 2001-05-02 Amersham Pharm Biotech Uk Ltd DNA isolation method
SE9903919D0 (sv) 1999-10-29 1999-10-29 Amersham Pharm Biotech Ab Device for dispensing droplets
AU778696B2 (en) * 1999-12-15 2004-12-16 Ge Healthcare Bio-Sciences Ab Compositions and methods for performing biological reactions
SE9904802D0 (sv) 1999-12-23 1999-12-23 Amersham Pharm Biotech Ab Microfluidic surfaces
US6884395B2 (en) 2000-05-12 2005-04-26 Gyros Ab Integrated microfluidic disc
SE0000300D0 (sv) 2000-01-30 2000-01-30 Amersham Pharm Biotech Ab Microfluidic assembly, covering method for the manufacture of the assembly and the use of the assembly
US6454868B1 (en) 2000-04-17 2002-09-24 Electrochemicals Inc. Permanganate desmear process for printed wiring boards
SE0001790D0 (sv) 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
US6734401B2 (en) * 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
WO2002000347A2 (en) 2000-06-28 2002-01-03 3M Innovative Properties Company Sample processing devices, systems and methods
US20030062358A1 (en) * 2000-07-19 2003-04-03 Atsushi Ito Semiconductor manufacturing/testing ceramic heater
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
SE0004594D0 (sv) 2000-12-12 2000-12-12 Gyros Ab Microscale nozzie
US6653625B2 (en) * 2001-03-19 2003-11-25 Gyros Ab Microfluidic system (MS)
US20040099310A1 (en) * 2001-01-05 2004-05-27 Per Andersson Microfluidic device
US6717136B2 (en) * 2001-03-19 2004-04-06 Gyros Ab Microfludic system (EDI)
JP4323806B2 (ja) * 2001-03-19 2009-09-02 ユィロス・パテント・アクチボラグ 反応可変要素の特徴付け
US6812456B2 (en) * 2001-03-19 2004-11-02 Gyros Ab Microfluidic system (EDI)
US7429354B2 (en) * 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
SE0104077D0 (sv) * 2001-10-21 2001-12-05 Gyros Ab A method and instrumentation for micro dispensation of droplets
US20030054563A1 (en) * 2001-09-17 2003-03-20 Gyros Ab Detector arrangement for microfluidic devices
SE0103108D0 (sv) 2001-09-17 2001-09-17 Gyros Microlabs Ab Rotary drive in an instrument for analysis of microscale liquid sample volumes
DE60237289D1 (de) * 2001-09-17 2010-09-23 Gyros Patent Ab Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
SE0103109D0 (sv) * 2001-09-17 2001-09-17 Gyros Microlabs Ab Detector arrangement with rotary drive in an instrument for analysis of microscale liquid sample volumes
US6728644B2 (en) * 2001-09-17 2004-04-27 Gyros Ab Method editor
US20050214442A1 (en) 2001-11-27 2005-09-29 Anders Larsson Surface and its manufacture and uses
US7238255B2 (en) * 2001-12-31 2007-07-03 Gyros Patent Ab Microfluidic device and its manufacture
US7221783B2 (en) * 2001-12-31 2007-05-22 Gyros Patent Ab Method and arrangement for reducing noise
WO2003082730A1 (en) * 2002-03-31 2003-10-09 Gyros Ab Efficient mmicrofluidic devices
WO2003087779A1 (en) * 2002-04-08 2003-10-23 Gyros Ab Homing process
US6955738B2 (en) * 2002-04-09 2005-10-18 Gyros Ab Microfluidic devices with new inner surfaces
WO2003093802A1 (en) 2002-04-30 2003-11-13 Gyros Ab Integrated microfluidic device (ea)
EP1509760A1 (en) 2002-05-31 2005-03-02 Gyros AB Detector arrangement based on surface plasmon resonance
SE0300822D0 (sv) 2003-03-23 2003-03-23 Gyros Ab A collection of Micro Scale Devices
JP5171034B2 (ja) 2003-03-23 2013-03-27 ユィロス・パテント・アクチボラグ 充填済みのマイクロスケール装置
US20050042770A1 (en) 2003-05-23 2005-02-24 Gyros Ab Fluidic functions based on non-wettable surfaces
US7776272B2 (en) 2003-10-03 2010-08-17 Gyros Patent Ab Liquid router
US8592219B2 (en) 2005-01-17 2013-11-26 Gyros Patent Ab Protecting agent

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Publication number Publication date
EP1349658B1 (en) 2010-01-27
JP4533581B2 (ja) 2010-09-01
DE60141223D1 (de) 2010-03-18
US7668443B2 (en) 2010-02-23
JP2004531360A (ja) 2004-10-14
AU2002223167A1 (en) 2002-06-03
EP1349658A1 (en) 2003-10-08
US20060083496A1 (en) 2006-04-20
US20040067051A1 (en) 2004-04-08
WO2002041997A1 (en) 2002-05-30
US6985672B2 (en) 2006-01-10
SE0004296D0 (sv) 2000-11-23
ATE456398T1 (de) 2010-02-15

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