CA2427809A1 - Enterotoxine nsp4 de rotavirus et ses methodes d'utilisation - Google Patents
Enterotoxine nsp4 de rotavirus et ses methodes d'utilisation Download PDFInfo
- Publication number
- CA2427809A1 CA2427809A1 CA002427809A CA2427809A CA2427809A1 CA 2427809 A1 CA2427809 A1 CA 2427809A1 CA 002427809 A CA002427809 A CA 002427809A CA 2427809 A CA2427809 A CA 2427809A CA 2427809 A1 CA2427809 A1 CA 2427809A1
- Authority
- CA
- Canada
- Prior art keywords
- nsp4
- peptide
- nucleic acid
- protein
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12311—Rotavirus, e.g. rotavirus A
- C12N2720/12322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention porte sur la glycoprotéine non structurelle de Rotavirus, NSP4, laquelle remplit différentes fonctions dans le cycle de réplication des virus, notamment au cours de la morphogenèse virale. Plus précisément, la NSP4 est un récepteur intracellulaire qui intervient dans le développement d'une enveloppe membranaire transitoire pendant la phase de bourgeonnement de nouvelles particules sous-virales dans le réticulum endoplasmique (ER). Ladite invention porte sur la NSP4 et ses méthodes d'utilisation. Elle a plus particulièrement trait à l'utilisation de la NSP4 et de fragments de celle-ci (NSP4 114-135, NSP4 120-147, NSP4 112-174, ou NSP4 112-150) dans la prévention ou le traitement de maladies à Rotavirus.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/705,621 US6673355B1 (en) | 1995-06-14 | 2000-11-03 | Rotavirus enterotoxin NSP4 and methods of using same |
US09/705,621 | 2000-11-03 | ||
PCT/US2001/045255 WO2002036172A2 (fr) | 2000-11-03 | 2001-11-02 | Enterotoxine nsp4 de rotavirus et ses methodes d'utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2427809A1 true CA2427809A1 (fr) | 2002-05-10 |
Family
ID=24834264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002427809A Abandoned CA2427809A1 (fr) | 2000-11-03 | 2001-11-02 | Enterotoxine nsp4 de rotavirus et ses methodes d'utilisation |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1349571A4 (fr) |
AU (1) | AU2002220025A1 (fr) |
CA (1) | CA2427809A1 (fr) |
WO (1) | WO2002036172A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1576877A1 (fr) * | 2004-03-04 | 2005-09-21 | Bioprotein Technologies | Production de protéines recombinantes de rotavirus dans le lait d'animaux transgéniques non-humains |
WO2007081447A2 (fr) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Antigènes de norovirus et de sapovirus |
HUE033858T2 (en) * | 2012-02-14 | 2018-01-29 | Merial Inc | Rotavirus unit vaccines and method for their preparation and use |
CN104661675B (zh) * | 2012-05-16 | 2019-04-30 | 阿德莱德研究创新私人有限公司 | 细胞疫苗和诱导受试者免疫反应的方法 |
EA201791683A1 (ru) * | 2015-01-23 | 2017-12-29 | Медикаго Инк. | Получение ротавирусоподобных частиц в растениях |
CN108504718A (zh) * | 2018-03-27 | 2018-09-07 | 东莞市第三人民医院 | 一种CaSR在RV、NSP4感染后的表达水平分析方法 |
CN117866858B (zh) * | 2023-11-30 | 2024-06-21 | 吉林农业大学 | 一种表达猪轮状病毒抗原的重组植物乳杆菌及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5186933A (en) * | 1986-12-30 | 1993-02-16 | Baylor College Of Medicine | Synthesis and immunogenicity of rotavirus genes using a baculovirus expression system |
US5298244A (en) * | 1990-10-25 | 1994-03-29 | University Of Saskatchewan | Assembled viral particles and their use in a vaccine to rotaviral disease |
AU6387196A (en) * | 1995-06-14 | 1997-01-15 | Baylor College Of Medicine | Rotavirus enterotoxin nsp4 and methods of using same |
AU1202201A (en) * | 1999-10-14 | 2001-04-23 | Baylor College Of Medicine | A novel adjuvant |
FR2806087B1 (fr) * | 2000-03-07 | 2002-10-18 | Agronomique Inst Nat Rech | Particules pseudovirales de rotavirus et leur utilisation pour vectoriser des proteines ou des acides nucleiques |
-
2001
- 2001-11-02 AU AU2002220025A patent/AU2002220025A1/en not_active Abandoned
- 2001-11-02 CA CA002427809A patent/CA2427809A1/fr not_active Abandoned
- 2001-11-02 WO PCT/US2001/045255 patent/WO2002036172A2/fr not_active Application Discontinuation
- 2001-11-02 EP EP01992588A patent/EP1349571A4/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2002036172A3 (fr) | 2002-09-19 |
AU2002220025A1 (en) | 2002-05-15 |
EP1349571A4 (fr) | 2005-02-16 |
EP1349571A2 (fr) | 2003-10-08 |
WO2002036172A2 (fr) | 2002-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |