CA2413884A1 - Rapid and sensitive detection of protein aggregation - Google Patents
Rapid and sensitive detection of protein aggregation Download PDFInfo
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- CA2413884A1 CA2413884A1 CA002413884A CA2413884A CA2413884A1 CA 2413884 A1 CA2413884 A1 CA 2413884A1 CA 002413884 A CA002413884 A CA 002413884A CA 2413884 A CA2413884 A CA 2413884A CA 2413884 A1 CA2413884 A1 CA 2413884A1
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
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- Immunology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Psychology (AREA)
- Pathology (AREA)
- Nanotechnology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60268900A | 2000-06-23 | 2000-06-23 | |
| US09/602,689 | 2000-06-23 | ||
| US63181800A | 2000-08-03 | 2000-08-03 | |
| US09/631,818 | 2000-08-03 | ||
| PCT/US2001/020232 WO2002001230A2 (en) | 2000-06-23 | 2001-06-25 | Rapid and sensitive detection of protein aggregation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2413884A1 true CA2413884A1 (en) | 2002-01-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002413884A Abandoned CA2413884A1 (en) | 2000-06-23 | 2001-06-25 | Rapid and sensitive detection of protein aggregation |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1356296B1 (enExample) |
| JP (4) | JP2004526124A (enExample) |
| AU (1) | AU2001270157A1 (enExample) |
| CA (1) | CA2413884A1 (enExample) |
| WO (1) | WO2002001230A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017063074A1 (en) * | 2015-10-14 | 2017-04-20 | University Health Network (Uhn) | Electrochemical assay for a protein analyte |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2413884A1 (en) * | 2000-06-23 | 2002-01-03 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of protein aggregation |
| AU2002216614A1 (en) | 2000-10-03 | 2002-04-15 | Minerva Biotechnologies Corporation | Electronic detection of interaction based on the interruption of flow |
| EP1336104B1 (en) * | 2000-11-01 | 2009-03-25 | Minerva Biotechnologies Corporation | Proteomics based drug comparison methods |
| JP4568840B2 (ja) * | 2004-12-28 | 2010-10-27 | 国立大学法人金沢大学 | アルツハイマー病の検査方法 |
| JP5164971B2 (ja) * | 2006-04-21 | 2013-03-21 | ピープルバイオ，アイ エヌ シー | 三次元的相互作用を用いてマルチマー形成ポリペプチドのモノマーからマルチマーを分別検出する方法 |
| JP2008032554A (ja) * | 2006-07-28 | 2008-02-14 | Japan Science & Technology Agency | βアミロイドオリゴマーを用いたバイオチップおよびアミロイドセンサーならびに生体試料中に存在するβアミロイドの検出方法 |
| JP4969236B2 (ja) * | 2006-12-22 | 2012-07-04 | ローム株式会社 | 生体分子または生体関連物質の測定方法 |
| AU2009246397B2 (en) | 2008-05-13 | 2013-01-17 | University Of Kansas | Metal abstraction peptide (MAP) tag and associated methods |
| JP5205293B2 (ja) * | 2009-01-19 | 2013-06-05 | 富士フイルム株式会社 | 抗体固定基板、並びに該抗体固定基板の製造方法及び利用 |
| CA2753586A1 (en) * | 2009-02-24 | 2010-09-02 | Winton G. Gibbons | Detection of complexes of tau and amyloid |
| EP2491391B1 (en) * | 2009-10-23 | 2018-02-28 | GE Healthcare Bio-Sciences AB | Method for determination of macromolecular multimers |
| WO2013081946A1 (en) | 2011-12-02 | 2013-06-06 | Plaxgen, Inc. | Plaque array method and compositions for forming and detecting plaques |
| WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
| KR101448353B1 (ko) | 2012-09-24 | 2014-10-10 | 한양대학교 산학협력단 | 단백질분해효소 활성 분석 방법 및 그 응용 |
| KR101451797B1 (ko) * | 2012-11-07 | 2014-10-16 | 가천대학교 산학협력단 | 멀티머-형성 폴리펩타이드의 멀티머 정량분석을 위한 표준 단백질 복합체 |
| JPWO2015159534A1 (ja) * | 2014-04-16 | 2017-04-13 | 富士フイルム株式会社 | 検出液及びそれを用いたバイオセンシング方法 |
| DE102015003404B4 (de) * | 2015-03-18 | 2021-10-07 | Forschungszentrum Jülich GmbH | Verfahren zur Herstellung eines Standards für den Nachweis von Proteinaggregaten einer Proteinfehlfaltungserkrankung sowie Standard und dessen Verwendung |
| CN111848470A (zh) * | 2016-08-05 | 2020-10-30 | 深圳深见医药科技有限公司 | 一种含金团簇的物质及其制备方法与应用 |
| US12352746B2 (en) | 2018-01-23 | 2025-07-08 | Oxford University Innovation Limited | Peptide-comprising electrode |
| CA3136356A1 (en) | 2019-04-12 | 2020-10-15 | Ecolab Usa Inc. | Antimicrobial multi-purpose cleaner and methods of making and using the same |
| WO2021075879A2 (ko) * | 2019-10-15 | 2021-04-22 | 고려대학교 산학협력단 | 단백질 응집체 검출용 형광 프로브 화합물 및 이를 포함하는 단백질 응집체 검출용 형광 센서 |
| CN115867807B (zh) | 2020-06-24 | 2025-10-31 | 旭化成生命科学股份有限公司 | 含蛋白质的溶液的评价方法 |
| CA3183682A1 (en) | 2020-06-26 | 2021-12-30 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
| WO2022221683A1 (en) * | 2021-04-16 | 2022-10-20 | Regents Of The University Of Minnesota | Methods and materials for detecting misfolded polypeptides |
| CA3248038A1 (en) | 2022-04-12 | 2023-10-19 | Minerva Biotechnologies Corporation | ANTI-MUC1* VARIABLE ANTIBODIES AND RELATED USES |
| JP2024142624A (ja) | 2023-03-30 | 2024-10-11 | セイコーエプソン株式会社 | 生体物質抽出用磁性ビーズ |
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| JPH0750112B2 (ja) * | 1988-04-26 | 1995-05-31 | 日本電信電話株式会社 | レーザ磁気免疫測定方法を実施するための検体調整方法 |
| IL85137A (en) * | 1987-01-21 | 1992-02-16 | Ares Serono Res & Dev Ltd | Method of assaying for a ligand using surface plasmon resonance effect |
| US5294369A (en) * | 1990-12-05 | 1994-03-15 | Akzo N.V. | Ligand gold bonding |
| US5369036A (en) * | 1992-07-02 | 1994-11-29 | Becton, Dickinson And Company | Enhancement of signal in immunoassays using microparticles which contain different detectable substances |
| JPH09511492A (ja) * | 1994-02-03 | 1997-11-18 | ザ ピコワー インスティテュート フォア メディカル リサーチ | アミロイドーシスの前進性グリコシル化終末産物仲介モジュレーション用組成物及び方法 |
| US5620850A (en) * | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| US6306584B1 (en) * | 1997-01-21 | 2001-10-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
| WO1998037421A1 (en) * | 1997-02-19 | 1998-08-27 | Regents Of The University Of Minnesota | Aβ DEPOSITION INHIBITOR SCREEN USING SYNTHETIC AMYLOID |
| DE19715483A1 (de) * | 1997-04-14 | 1998-10-15 | Boehringer Mannheim Gmbh | Methode zur gleichzeitigen Bestimmung von biomolekularen Wechselwirkungen mittels Plasmonenresonanz undFluoreszenzdetektion |
| JPH1132764A (ja) * | 1997-07-14 | 1999-02-09 | Yakult Honsha Co Ltd | ビフィドバクテリウム・ブレーベ用モノクローナル抗体 |
| JP2001515044A (ja) * | 1997-08-14 | 2001-09-18 | ザ・レジェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア | 蛍光アミロイドＡβペプチドとその使用 |
| WO2000024941A1 (en) * | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| JP5122705B2 (ja) * | 1999-01-25 | 2013-01-16 | ミナーヴァ・バイオテクノロジーズ・コーポレーション | 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出 |
| CA2413884A1 (en) * | 2000-06-23 | 2002-01-03 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of protein aggregation |
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2001
- 2001-06-25 CA CA002413884A patent/CA2413884A1/en not_active Abandoned
- 2001-06-25 JP JP2002506112A patent/JP2004526124A/ja active Pending
- 2001-06-25 WO PCT/US2001/020232 patent/WO2002001230A2/en not_active Ceased
- 2001-06-25 AU AU2001270157A patent/AU2001270157A1/en not_active Abandoned
- 2001-06-25 EP EP01948711.5A patent/EP1356296B1/en not_active Expired - Lifetime
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2013
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2014
- 2014-11-27 JP JP2014240068A patent/JP2015096855A/ja not_active Withdrawn
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2017
- 2017-02-03 JP JP2017018410A patent/JP6662797B2/ja not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017063074A1 (en) * | 2015-10-14 | 2017-04-20 | University Health Network (Uhn) | Electrochemical assay for a protein analyte |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002001230A2 (en) | 2002-01-03 |
| AU2001270157A1 (en) | 2002-01-08 |
| JP2014013242A (ja) | 2014-01-23 |
| JP2004526124A (ja) | 2004-08-26 |
| JP2017122728A (ja) | 2017-07-13 |
| EP1356296B1 (en) | 2016-04-20 |
| WO2002001230A3 (en) | 2003-08-14 |
| EP1356296A2 (en) | 2003-10-29 |
| JP6662797B2 (ja) | 2020-03-11 |
| JP2015096855A (ja) | 2015-05-21 |
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