AU2001270157A1 - Rapid and sensitive detection of protein aggregation - Google Patents

Rapid and sensitive detection of protein aggregation

Info

Publication number
AU2001270157A1
AU2001270157A1 AU2001270157A AU7015701A AU2001270157A1 AU 2001270157 A1 AU2001270157 A1 AU 2001270157A1 AU 2001270157 A AU2001270157 A AU 2001270157A AU 7015701 A AU7015701 A AU 7015701A AU 2001270157 A1 AU2001270157 A1 AU 2001270157A1
Authority
AU
Australia
Prior art keywords
species
binding
aggregate
forming
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001270157A
Other languages
English (en)
Inventor
Cynthia C. Bamdad
R. Shoshana Bamdad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Minerva Biotechnologies Corp
Original Assignee
Minerva Biotechnologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minerva Biotechnologies Corp filed Critical Minerva Biotechnologies Corp
Publication of AU2001270157A1 publication Critical patent/AU2001270157A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Psychology (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
AU2001270157A 1999-01-25 2001-06-25 Rapid and sensitive detection of protein aggregation Abandoned AU2001270157A1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US60117126 1999-01-25
US60132288 1999-05-03
US60155937 1999-09-24
US60268900A 2000-06-23 2000-06-23
US09602689 2000-06-23
US63181800A 2000-08-03 2000-08-03
US09631818 2000-08-03
PCT/US2001/020232 WO2002001230A2 (en) 2000-06-23 2001-06-25 Rapid and sensitive detection of protein aggregation

Publications (1)

Publication Number Publication Date
AU2001270157A1 true AU2001270157A1 (en) 2002-01-08

Family

ID=27084216

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001270157A Abandoned AU2001270157A1 (en) 1999-01-25 2001-06-25 Rapid and sensitive detection of protein aggregation

Country Status (5)

Country Link
EP (1) EP1356296B1 (enExample)
JP (4) JP2004526124A (enExample)
AU (1) AU2001270157A1 (enExample)
CA (1) CA2413884A1 (enExample)
WO (1) WO2002001230A2 (enExample)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
CA2413884A1 (en) * 2000-06-23 2002-01-03 Minerva Biotechnologies Corporation Rapid and sensitive detection of protein aggregation
AU2002216614A1 (en) 2000-10-03 2002-04-15 Minerva Biotechnologies Corporation Electronic detection of interaction based on the interruption of flow
EP1336104B1 (en) * 2000-11-01 2009-03-25 Minerva Biotechnologies Corporation Proteomics based drug comparison methods
JP4568840B2 (ja) * 2004-12-28 2010-10-27 国立大学法人金沢大学 アルツハイマー病の検査方法
JP5164971B2 (ja) * 2006-04-21 2013-03-21 ピープルバイオ，アイ エヌ シー 三次元的相互作用を用いてマルチマー形成ポリペプチドのモノマーからマルチマーを分別検出する方法
JP2008032554A (ja) * 2006-07-28 2008-02-14 Japan Science & Technology Agency βアミロイドオリゴマーを用いたバイオチップおよびアミロイドセンサーならびに生体試料中に存在するβアミロイドの検出方法
JP4969236B2 (ja) * 2006-12-22 2012-07-04 ローム株式会社 生体分子または生体関連物質の測定方法
AU2009246397B2 (en) 2008-05-13 2013-01-17 University Of Kansas Metal abstraction peptide (MAP) tag and associated methods
JP5205293B2 (ja) * 2009-01-19 2013-06-05 富士フイルム株式会社 抗体固定基板、並びに該抗体固定基板の製造方法及び利用
CA2753586A1 (en) * 2009-02-24 2010-09-02 Winton G. Gibbons Detection of complexes of tau and amyloid
EP2491391B1 (en) * 2009-10-23 2018-02-28 GE Healthcare Bio-Sciences AB Method for determination of macromolecular multimers
WO2013081946A1 (en) 2011-12-02 2013-06-06 Plaxgen, Inc. Plaque array method and compositions for forming and detecting plaques
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
KR101448353B1 (ko) 2012-09-24 2014-10-10 한양대학교 산학협력단 단백질분해효소 활성 분석 방법 및 그 응용
KR101451797B1 (ko) * 2012-11-07 2014-10-16 가천대학교 산학협력단 멀티머-형성 폴리펩타이드의 멀티머 정량분석을 위한 표준 단백질 복합체
JPWO2015159534A1 (ja) * 2014-04-16 2017-04-13 富士フイルム株式会社 検出液及びそれを用いたバイオセンシング方法
DE102015003404B4 (de) * 2015-03-18 2021-10-07 Forschungszentrum Jülich GmbH Verfahren zur Herstellung eines Standards für den Nachweis von Proteinaggregaten einer Proteinfehlfaltungserkrankung sowie Standard und dessen Verwendung
EP3362785A4 (en) * 2015-10-14 2019-06-12 University Health Network (UHN) ELECTROCHEMICAL TEST FOR A PROTEIN ANALYTE
CN111848470A (zh) * 2016-08-05 2020-10-30 深圳深见医药科技有限公司 一种含金团簇的物质及其制备方法与应用
US12352746B2 (en) 2018-01-23 2025-07-08 Oxford University Innovation Limited Peptide-comprising electrode
CA3136356A1 (en) 2019-04-12 2020-10-15 Ecolab Usa Inc. Antimicrobial multi-purpose cleaner and methods of making and using the same
WO2021075879A2 (ko) * 2019-10-15 2021-04-22 고려대학교 산학협력단 단백질 응집체 검출용 형광 프로브 화합물 및 이를 포함하는 단백질 응집체 검출용 형광 센서
CN115867807B (zh) 2020-06-24 2025-10-31 旭化成生命科学股份有限公司 含蛋白质的溶液的评价方法
CA3183682A1 (en) 2020-06-26 2021-12-30 Minerva Biotechnologies Corporation Anti-nme antibody and method of treating cancer or cancer metastasis
WO2022221683A1 (en) * 2021-04-16 2022-10-20 Regents Of The University Of Minnesota Methods and materials for detecting misfolded polypeptides
CA3248038A1 (en) 2022-04-12 2023-10-19 Minerva Biotechnologies Corporation ANTI-MUC1* VARIABLE ANTIBODIES AND RELATED USES
JP2024142624A (ja) 2023-03-30 2024-10-11 セイコーエプソン株式会社 生体物質抽出用磁性ビーズ

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JPH09511492A (ja) * 1994-02-03 1997-11-18 ザ ピコワー インスティテュート フォア メディカル リサーチ アミロイドーシスの前進性グリコシル化終末産物仲介モジュレーション用組成物及び方法
US5620850A (en) * 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US6306584B1 (en) * 1997-01-21 2001-10-23 President And Fellows Of Harvard College Electronic-property probing of biological molecules at surfaces
WO1998037421A1 (en) * 1997-02-19 1998-08-27 Regents Of The University Of Minnesota Aβ DEPOSITION INHIBITOR SCREEN USING SYNTHETIC AMYLOID
DE19715483A1 (de) * 1997-04-14 1998-10-15 Boehringer Mannheim Gmbh Methode zur gleichzeitigen Bestimmung von biomolekularen Wechselwirkungen mittels Plasmonenresonanz undFluoreszenzdetektion
JPH1132764A (ja) * 1997-07-14 1999-02-09 Yakult Honsha Co Ltd ビフィドバクテリウム・ブレーベ用モノクローナル抗体
JP2001515044A (ja) * 1997-08-14 2001-09-18 ザ・レジェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア 蛍光アミロイドＡβペプチドとその使用
WO2000024941A1 (en) * 1998-10-27 2000-05-04 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
JP5122705B2 (ja) * 1999-01-25 2013-01-16 ミナーヴァ・バイオテクノロジーズ・コーポレーション 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出
CA2413884A1 (en) * 2000-06-23 2002-01-03 Minerva Biotechnologies Corporation Rapid and sensitive detection of protein aggregation

Also Published As

Publication number Publication date
WO2002001230A2 (en) 2002-01-03
JP2014013242A (ja) 2014-01-23
JP2004526124A (ja) 2004-08-26
JP2017122728A (ja) 2017-07-13
EP1356296B1 (en) 2016-04-20
WO2002001230A3 (en) 2003-08-14
EP1356296A2 (en) 2003-10-29
CA2413884A1 (en) 2002-01-03
JP6662797B2 (ja) 2020-03-11
JP2015096855A (ja) 2015-05-21

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