CA2396209C - The use of mirtazapine for the treatment of sleep disorders - Google Patents

The use of mirtazapine for the treatment of sleep disorders Download PDF

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Publication number
CA2396209C
CA2396209C CA002396209A CA2396209A CA2396209C CA 2396209 C CA2396209 C CA 2396209C CA 002396209 A CA002396209 A CA 002396209A CA 2396209 A CA2396209 A CA 2396209A CA 2396209 C CA2396209 C CA 2396209C
Authority
CA
Canada
Prior art keywords
mirtazapine
treatment
sleep
dose
unit dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002396209A
Other languages
English (en)
French (fr)
Other versions
CA2396209A1 (en
Inventor
Gerardus Stephanus Franciscus Ruigt
Frans Van Den Berg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme BV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Publication of CA2396209A1 publication Critical patent/CA2396209A1/en
Application granted granted Critical
Publication of CA2396209C publication Critical patent/CA2396209C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002396209A 2000-02-11 2001-02-06 The use of mirtazapine for the treatment of sleep disorders Expired - Lifetime CA2396209C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00200499.2 2000-02-11
EP00200499 2000-02-11
PCT/EP2001/001221 WO2001058453A1 (en) 2000-02-11 2001-02-06 The use of mirtazapine for the treatment of sleep disorders

Publications (2)

Publication Number Publication Date
CA2396209A1 CA2396209A1 (en) 2001-08-16
CA2396209C true CA2396209C (en) 2009-09-01

Family

ID=8171013

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002396209A Expired - Lifetime CA2396209C (en) 2000-02-11 2001-02-06 The use of mirtazapine for the treatment of sleep disorders

Country Status (25)

Country Link
US (1) US6933293B2 (enExample)
EP (4) EP2283840A1 (enExample)
JP (1) JP5039994B2 (enExample)
KR (1) KR20020069371A (enExample)
CN (2) CN1395487A (enExample)
AR (1) AR027394A1 (enExample)
AT (1) ATE317261T1 (enExample)
AU (1) AU780439B2 (enExample)
BR (1) BR0108261A (enExample)
CA (1) CA2396209C (enExample)
CO (1) CO5271706A1 (enExample)
CZ (1) CZ302368B6 (enExample)
DE (1) DE60117122T2 (enExample)
DK (1) DK1257278T3 (enExample)
ES (1) ES2258071T3 (enExample)
HK (1) HK1049122B (enExample)
HU (1) HUP0204391A3 (enExample)
IL (2) IL150290A0 (enExample)
NO (1) NO328007B1 (enExample)
PE (1) PE20011080A1 (enExample)
PL (1) PL206073B1 (enExample)
RU (1) RU2270680C2 (enExample)
SK (1) SK287396B6 (enExample)
WO (1) WO2001058453A1 (enExample)
ZA (1) ZA200205238B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040152055A1 (en) * 2003-01-30 2004-08-05 Gliessner Michael J.G. Video based language learning system
UA83666C2 (ru) 2003-07-10 2008-08-11 Н.В. Органон Способ получения энантиомерно чистого миртазапина
WO2005051349A2 (en) * 2003-11-25 2005-06-09 Aurobindo Pharma Ltd. Pharmaceutical compositions of mirtazapine
GB0417558D0 (en) * 2004-08-06 2004-09-08 Merck Sharp & Dohme Novel combination therapy
CN101039664A (zh) * 2004-10-14 2007-09-19 大金工业株式会社 气氛改变方法、用于该气氛改变方法的喷雾剂与喷雾装置
JP2006137748A (ja) * 2004-10-14 2006-06-01 Daikin Ind Ltd 雰囲気改変方法、並びに、それに用いられる噴霧剤及び噴霧装置
JP2007284363A (ja) * 2006-04-13 2007-11-01 Daikin Ind Ltd 噴霧剤
MX2009010967A (es) 2007-04-11 2009-12-15 Organon Nv Un metodo para la preparacion de mirtazapina.
US10603272B2 (en) 2015-02-27 2020-03-31 Kindred Biosciences, Inc. Stimulation of appetite and treatment of anorexia in dogs and cats
CN111053735A (zh) * 2020-02-25 2020-04-24 上海阶平医院管理有限公司 一种治疗失眠的冷敷凝胶

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
AU678401B2 (en) * 1992-10-07 1997-05-29 Akzo Nobel N.V. Process for separating enantiomers from a racemic mixture
EP0813873B1 (en) * 1996-06-19 2002-02-13 Akzo Nobel N.V. Pharmaceutical composition comprising mirtazapine and one or more selective serotonin reuptake inhibitors
IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
ATE289816T1 (de) * 1997-11-14 2005-03-15 Akzo Nobel Nv Verwendung von mirtazapine zur herstellung eines medikaments zur behandlung von schlafapnoen

Also Published As

Publication number Publication date
AU3024701A (en) 2001-08-20
DE60117122T2 (de) 2006-07-27
CN101229170A (zh) 2008-07-30
IL150290A (en) 2010-12-30
ATE317261T1 (de) 2006-02-15
HUP0204391A3 (en) 2005-03-29
PL206073B1 (pl) 2010-06-30
DK1257278T3 (da) 2006-06-12
RU2002124141A (ru) 2004-03-10
EP1257278B1 (en) 2006-02-08
EP1658850A1 (en) 2006-05-24
IL150290A0 (en) 2002-12-01
NO328007B1 (no) 2009-11-09
JP5039994B2 (ja) 2012-10-03
PL356721A1 (en) 2004-06-28
CA2396209A1 (en) 2001-08-16
EP1656937A1 (en) 2006-05-17
SK287396B6 (sk) 2010-08-09
US20030022888A1 (en) 2003-01-30
RU2270680C2 (ru) 2006-02-27
WO2001058453A1 (en) 2001-08-16
EP2283840A1 (en) 2011-02-16
AU780439B2 (en) 2005-03-24
CO5271706A1 (es) 2003-04-30
KR20020069371A (ko) 2002-08-30
NO20023803L (no) 2002-10-09
CZ302368B6 (cs) 2011-04-13
SK11442002A3 (sk) 2003-02-04
BR0108261A (pt) 2003-03-05
CN1395487A (zh) 2003-02-05
EP1257278A1 (en) 2002-11-20
DE60117122D1 (de) 2006-04-20
PE20011080A1 (es) 2001-10-18
AR027394A1 (es) 2003-03-26
CZ20022330A3 (cs) 2002-11-13
NO20023803D0 (no) 2002-08-09
HK1049122B (en) 2006-04-21
ZA200205238B (en) 2003-09-29
HUP0204391A2 (en) 2003-05-28
JP2003522147A (ja) 2003-07-22
HK1049122A1 (en) 2003-05-02
US6933293B2 (en) 2005-08-23
ES2258071T3 (es) 2006-08-16

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Effective date: 20210208