CA2392620C - Use of melatonin for the treatment of androgenetic and diffuse alopecia - Google Patents

Use of melatonin for the treatment of androgenetic and diffuse alopecia Download PDF

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Publication number
CA2392620C
CA2392620C CA002392620A CA2392620A CA2392620C CA 2392620 C CA2392620 C CA 2392620C CA 002392620 A CA002392620 A CA 002392620A CA 2392620 A CA2392620 A CA 2392620A CA 2392620 C CA2392620 C CA 2392620C
Authority
CA
Canada
Prior art keywords
hair
melatonin
alopecia
telogenic
rate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002392620A
Other languages
English (en)
French (fr)
Other versions
CA2392620A1 (en
Inventor
Peter Elsner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASAT AG Applied Science and Technology
Original Assignee
ASAT AG Applied Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASAT AG Applied Science and Technology filed Critical ASAT AG Applied Science and Technology
Publication of CA2392620A1 publication Critical patent/CA2392620A1/en
Application granted granted Critical
Publication of CA2392620C publication Critical patent/CA2392620C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002392620A 1999-11-30 2000-11-29 Use of melatonin for the treatment of androgenetic and diffuse alopecia Expired - Fee Related CA2392620C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19957710A DE19957710A1 (de) 1999-11-30 1999-11-30 Verwendung von Melatonin zur Behandlung der androgenetischen Alopezie
DE19957710.2 1999-11-30
US09/506,442 US6281241B1 (en) 1999-11-30 2000-02-18 Use of melatonin for the treatment of androgenetic alopecia
US09/506,442 2000-02-18
PCT/EP2000/011976 WO2001039771A1 (de) 1999-11-30 2000-11-29 Verwendung von melatonin zur behandlung der androgenetischen und diffusen alopezie

Publications (2)

Publication Number Publication Date
CA2392620A1 CA2392620A1 (en) 2001-06-07
CA2392620C true CA2392620C (en) 2009-10-13

Family

ID=7930930

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392620A Expired - Fee Related CA2392620C (en) 1999-11-30 2000-11-29 Use of melatonin for the treatment of androgenetic and diffuse alopecia

Country Status (12)

Country Link
US (2) US6281241B1 (https=)
EP (1) EP1235571B1 (https=)
JP (1) JP4713805B2 (https=)
AT (1) ATE275400T1 (https=)
AU (1) AU2838101A (https=)
CA (1) CA2392620C (https=)
DE (2) DE19957710A1 (https=)
DK (1) DK1235571T3 (https=)
ES (1) ES2228663T3 (https=)
PT (1) PT1235571E (https=)
TR (1) TR200402628T4 (https=)
WO (1) WO2001039771A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19957710A1 (de) * 1999-11-30 2001-05-31 Asat Ag Applied Science & Tech Verwendung von Melatonin zur Behandlung der androgenetischen Alopezie
US7015072B2 (en) 2001-07-11 2006-03-21 Asat Limited Method of manufacturing an enhanced thermal dissipation integrated circuit package
US6734552B2 (en) 2001-07-11 2004-05-11 Asat Limited Enhanced thermal dissipation integrated circuit package
US6790710B2 (en) 2002-01-31 2004-09-14 Asat Limited Method of manufacturing an integrated circuit package
US20030178719A1 (en) * 2002-03-22 2003-09-25 Combs Edward G. Enhanced thermal dissipation integrated circuit package and method of manufacturing enhanced thermal dissipation integrated circuit package
US6940154B2 (en) * 2002-06-24 2005-09-06 Asat Limited Integrated circuit package and method of manufacturing the integrated circuit package
SI1569724T1 (sl) * 2002-10-30 2009-04-30 Asat Ag Applied Science & Tech Formulacije, ki vsebujejo melatonin, dvokrpi ginko in biotin
PT1569724E (pt) * 2002-10-30 2009-04-03 Asat Ag Applied Science & Tech Formulações contendo melatonina, ginkgo biloba e biotina
US20050249785A1 (en) * 2003-08-13 2005-11-10 Gordon John G Use of melatonin-containing oral supplement with animals
CA2556753C (en) * 2004-02-20 2014-11-25 Lifescape Biosciences Incorporated Compositions and methods for sleep regulation
JP3964417B2 (ja) * 2004-09-27 2007-08-22 国立大学法人金沢大学 インドール誘導体を有効成分とするα２受容体遮断剤及び血管拡張剤
US20080059313A1 (en) * 2006-08-30 2008-03-06 Oblong John E Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair
ITGE20070009A1 (it) * 2007-01-24 2008-07-25 Leila Baeram Composizione cosmetica e metodo per favorire la ricrescita dei capelli.
US20100120871A1 (en) * 2008-11-10 2010-05-13 Dawson Jr Thomas Larry Hair care compositions, methods, and articles of commerce that can increase the appearance of thicker and fuller hair
GB0918564D0 (en) 2009-10-22 2009-12-09 Plasticell Ltd Nested cell encapsulation
WO2011109459A2 (en) * 2010-03-04 2011-09-09 University Of Miami Compositions, kits and methods for determining efficacy of a therapeutic agent and treating hair and skin diseases
ITMI20112432A1 (it) * 2011-12-30 2013-07-01 Bionest Ltd Kit per il trattamento e la prevenzione dell'alopecia
US11696883B2 (en) 2014-05-23 2023-07-11 Triple Hair Inc. Compositions for reducing hair loss and/or increasing hair regrowth
WO2015176161A1 (en) 2014-05-23 2015-11-26 Triple Hair Inc. Compositions for reducing hair loss and/or increasing hair regrowth
JP2018512440A (ja) 2015-04-14 2018-05-17 バイチュラス バイオテック，ソシエダ リミタダ 皮膚細胞に対する若返り活性および／または創傷治癒活性を有する無細胞植物細胞培養懸濁液上清
ES2902842T3 (es) 2015-07-08 2022-03-30 Triple Hair Inc Composición que comprende resveratrol y melatonina para reducir la caída y/o aumentar el crecimiento del cabello
JP7118425B2 (ja) 2016-04-11 2022-08-16 バイチュラス バイオテック，ソシエダ リミタダ 脱毛の予防及び／又は治療のためのペプチド及び医薬組成物、栄養補助組成物、又は獣医学組成物
GB201707143D0 (en) 2017-05-04 2017-06-21 Plasticell Ltd Method for producing cells
GB2638109A (en) * 2022-06-20 2025-08-20 John Hemming Trading Ltd Cell differentiation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340579A (en) * 1984-11-20 1994-08-23 Farmaka S.R.L. Method of treating dermatological conditions
US4746674A (en) 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
JPS61212512A (ja) * 1985-03-19 1986-09-20 Shiseido Co Ltd 養毛料
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
FR2717381B1 (fr) * 1994-03-15 1996-04-19 Oreal Compositions à base d'alpha-pyrones pour induire et stimuler la croissance des cheveux et/ou freiner leur chute et utilisation.
JP3108586B2 (ja) * 1994-06-01 2000-11-13 富士産業株式会社 育毛剤
US5597575A (en) * 1994-06-06 1997-01-28 Breitbarth; Richard Composition for stimulating and inducing hair growth
DE19509354A1 (de) * 1994-12-08 1996-06-13 Klett Loch Lore M Kombinationspräparat zur Förderung des Haarwachstums und ggf. des Haut- und Nagelwachstums sowie zur Verhinderung bzw. zur Beseitigung von Haarausfall
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
ES2101660B1 (es) * 1995-12-21 1997-12-16 Soler Armando Jose Yanez Nuevo crecepelo de uso topico.
GB2314019B (en) * 1996-06-10 2000-03-15 Bio Scient Ltd The use of L-Lysine in the treatment of hair loss
FR2751539B1 (fr) * 1996-07-25 1998-12-04 Oreal Nouvelles compositions topiques comprenant de tres faibles doses de melatonine ou ses derives et leur utilisation en cosmetique
WO1998005298A1 (es) * 1996-08-02 1998-02-12 Universidad De Granada Desarrollo de productos cosmeticos para uso humano a base de melatonina como producto activo
FR2754454B1 (fr) * 1996-10-10 1998-11-27 Oreal Utilisation d'au moins un glycol comme agent de solubilisation de la melatonine dans l'eau et compositions obtenues
FR2756832B1 (fr) * 1996-12-06 1999-01-08 Oreal Utilisation de melatonine dans une composition pour stabiliser les polymeres gelifiants hydrophiles
US5958964A (en) * 1997-02-18 1999-09-28 South Alabama Medical Science Foundation Use of melatonin to prevent cytotoxic effects of amyloid beta protein
US6030948A (en) * 1997-12-19 2000-02-29 Mann; Morris A. Hair regeneration compositions for treatment of alopecia and methods of application related thereto
US6274615B1 (en) * 1998-03-25 2001-08-14 South Alabama Medical Science Foundation Method for delaying the onset of alheimer's disease and for treatment or delaying the onset of other amyloidosis-related diseases/disorders
DE19957710A1 (de) * 1999-11-30 2001-05-31 Asat Ag Applied Science & Tech Verwendung von Melatonin zur Behandlung der androgenetischen Alopezie
US6747008B1 (en) * 2000-06-19 2004-06-08 University Of Southern California Methods for treating and preventing alopecia
FR2811550B1 (fr) * 2000-07-11 2003-02-14 Oreal Composition a base de vitamines et de sels mineraux, pour diminuer la chute des cheveux et/ou favoriser la repousse des cheveux

Also Published As

Publication number Publication date
DE50007706D1 (de) 2004-10-14
PT1235571E (pt) 2004-12-31
JP4713805B2 (ja) 2011-06-29
DK1235571T3 (da) 2005-01-17
EP1235571A1 (de) 2002-09-04
CA2392620A1 (en) 2001-06-07
AU2838101A (en) 2001-06-12
US20020183377A1 (en) 2002-12-05
JP2004500353A (ja) 2004-01-08
TR200402628T4 (tr) 2004-11-22
DE19957710A1 (de) 2001-05-31
ATE275400T1 (de) 2004-09-15
ES2228663T3 (es) 2005-04-16
EP1235571B1 (de) 2004-09-08
WO2001039771A1 (de) 2001-06-07
US6281241B1 (en) 2001-08-28

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20181129