CA2389953A1 - New functionalized polymeric reagents - Google Patents

New functionalized polymeric reagents Download PDF

Info

Publication number
CA2389953A1
CA2389953A1 CA002389953A CA2389953A CA2389953A1 CA 2389953 A1 CA2389953 A1 CA 2389953A1 CA 002389953 A CA002389953 A CA 002389953A CA 2389953 A CA2389953 A CA 2389953A CA 2389953 A1 CA2389953 A1 CA 2389953A1
Authority
CA
Canada
Prior art keywords
functionalized polymeric
reagent
polymeric reagent
solution
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002389953A
Other languages
English (en)
French (fr)
Inventor
Patrick Page
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2389953A1 publication Critical patent/CA2389953A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C291/00—Compounds containing carbon and nitrogen and having functional groups not covered by groups C07C201/00 - C07C281/00
    • C07C291/10—Isocyanides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/88—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00—Methods specially adapted for identifying library members
    • C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Structural Engineering (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002389953A 1999-11-22 2000-11-16 New functionalized polymeric reagents Abandoned CA2389953A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904222-8 1999-11-22
SE9904222A SE519326C2 (sv) 1999-11-22 1999-11-22 Funktionaliserade polymera reagens innefattande en syralabil isonitrildel samt förfarande för dess framställning
PCT/SE2000/002263 WO2001037983A1 (en) 1999-11-22 2000-11-16 New functionalized polymeric reagents

Publications (1)

Publication Number Publication Date
CA2389953A1 true CA2389953A1 (en) 2001-05-31

Family

ID=20417810

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002389953A Abandoned CA2389953A1 (en) 1999-11-22 2000-11-16 New functionalized polymeric reagents

Country Status (6)

Country Link
EP (1) EP1239949A1 (sv)
JP (1) JP2003514876A (sv)
AU (1) AU769893B2 (sv)
CA (1) CA2389953A1 (sv)
SE (1) SE519326C2 (sv)
WO (1) WO2001037983A1 (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10150077B4 (de) * 2001-10-10 2004-07-29 Morphochem Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung polymergebundener Isonitrile
DE10162134A1 (de) * 2001-12-18 2003-07-10 Morphochem Ag Ag Fuer Kombinat Harzgebundene Isonitrile
FR2856061A1 (fr) * 2003-06-11 2004-12-17 Chrysalon Derives polycycliques ortho-condenses de l'aminopyrrole a substituant electroattracteur chimiotheques combinatoires desdits derives et leur procede d'obtention
MXPA06014307A (es) 2004-06-08 2007-03-12 Alza Corp Preparacion de conjugados macromoleculares por reaccion de condensacion de cuatro componentes.
CN104245794A (zh) * 2011-12-16 2014-12-24 麻省理工学院 α-氨基脒聚合物及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812532A (en) * 1987-07-29 1989-03-14 Bio-Affinity Systems, Inc. Solid phase oxime reagent
WO1999025752A1 (en) * 1997-11-18 1999-05-27 Aventis Pharmaceuticals Products Inc. Functionalized resin for the synthesis of amides and peptides

Also Published As

Publication number Publication date
AU1907401A (en) 2001-06-04
WO2001037983A1 (en) 2001-05-31
AU769893B2 (en) 2004-02-05
SE9904222D0 (sv) 1999-11-22
JP2003514876A (ja) 2003-04-22
SE9904222L (sv) 2001-05-23
SE519326C2 (sv) 2003-02-11
EP1239949A1 (en) 2002-09-18

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Legal Events

Date Code Title Description
FZDE Discontinued