CA2381004A1 - Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins - Google Patents
Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins Download PDFInfo
- Publication number
- CA2381004A1 CA2381004A1 CA002381004A CA2381004A CA2381004A1 CA 2381004 A1 CA2381004 A1 CA 2381004A1 CA 002381004 A CA002381004 A CA 002381004A CA 2381004 A CA2381004 A CA 2381004A CA 2381004 A1 CA2381004 A1 CA 2381004A1
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- Prior art keywords
- nucleic acid
- artificial sequence
- acid ligand
- rna
- hgf
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- G01N2333/475—Assays involving growth factors
- G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53642890A | 1990-06-11 | 1990-06-11 | |
| US09/364,543 | 1999-07-29 | ||
| US09/364,539 US6344321B1 (en) | 1990-06-11 | 1999-07-29 | Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met |
| US09/364,539 | 1999-07-29 | ||
| US09/364,543 US6331394B1 (en) | 1991-06-10 | 1999-07-29 | Nucleic acid ligands to integrins |
| PCT/US2000/020139 WO2001009159A1 (en) | 1990-06-11 | 2000-07-24 | Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2381004A1 true CA2381004A1 (en) | 2001-02-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002381004A Abandoned CA2381004A1 (en) | 1990-06-11 | 2000-07-24 | Nucleic acid ligands to hepatocyte growth factor/scatter factor (hgf/sf) or its receptor c-met and to integrins |
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| Country | Link |
|---|---|
| US (2) | US6344321B1 (enExample) |
| EP (1) | EP1203007B1 (enExample) |
| JP (1) | JP2003506024A (enExample) |
| CA (1) | CA2381004A1 (enExample) |
| WO (1) | WO2001009159A1 (enExample) |
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| CA2328356A1 (en) | 1999-12-22 | 2001-06-22 | Itty Atcravi | Recreational vehicles |
| US7645743B2 (en) * | 1999-12-22 | 2010-01-12 | Altermune, Llc | Chemically programmable immunity |
| EP2322648A1 (en) * | 2000-09-26 | 2011-05-18 | Duke University | RNA aptamers and methods for identifying the same |
| US20030118585A1 (en) | 2001-10-17 | 2003-06-26 | Agy Therapeutics | Use of protein biomolecular targets in the treatment and visualization of brain tumors |
| IL159053A0 (en) | 2001-05-25 | 2004-05-12 | Univ Duke | Modulators of pharmacological agents |
| US10590418B2 (en) | 2001-07-23 | 2020-03-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for RNAi mediated inhibition of gene expression in mammals |
| CA2936534C (en) | 2001-07-23 | 2021-01-26 | The Board Of Trustees Of Leland Stanford Junior University | Methods and compositions for rnai mediated inhibition of gene expression in mammals |
| US7435542B2 (en) * | 2002-06-24 | 2008-10-14 | Cornell Research Foundation, Inc. | Exhaustive selection of RNA aptamers against complex targets |
| US8853376B2 (en) | 2002-11-21 | 2014-10-07 | Archemix Llc | Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics |
| US7670631B2 (en) * | 2003-03-12 | 2010-03-02 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Method for the prevention of malaria infection of humans by hepatocyte growth factor antagonists |
| EP1620547B1 (en) * | 2003-04-21 | 2014-06-18 | Archemix LLC | Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics |
| US7727969B2 (en) * | 2003-06-06 | 2010-06-01 | Massachusetts Institute Of Technology | Controlled release nanoparticle having bound oligonucleotide for targeted delivery |
| ES2323425T3 (es) * | 2003-06-06 | 2009-07-15 | Genentech, Inc. | Modulacion de la interaccion entre la cadena beta de hgf y c-met. |
| US20050123932A1 (en) * | 2003-12-09 | 2005-06-09 | Mekbib Astatke | Nucleic acid-chelating agent conjugates |
| EP1756138A4 (en) * | 2004-03-05 | 2009-07-01 | Archemix Corp | HUMAN CYTOKINE FAMILY BINDING APTAMERS AND THEIR USE AS THERAPEUTIC AGENTS OF AUTOIMMUNE DISEASES |
| US20060193821A1 (en) * | 2004-03-05 | 2006-08-31 | Diener John L | Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics |
| JP2007532662A (ja) * | 2004-04-13 | 2007-11-15 | （オーエスアイ）アイテツク・インコーポレーテツド | 高分子量の立体的な基へ抱合された核酸アプタマー |
| US7989613B2 (en) * | 2004-10-19 | 2011-08-02 | Texas Tech University | Inhibition of metallo-β-lactamase by RNA |
| KR20080036595A (ko) * | 2005-07-05 | 2008-04-28 | 가부시키가이샤 리보믹 | 면역글로불린 ｇ에 결합하는 핵산과 그 이용법 |
| JP4910195B2 (ja) * | 2005-07-05 | 2012-04-04 | 株式会社リボミック | 免疫グロブリンｇに結合する核酸とその利用法 |
| DK1994171T3 (en) * | 2006-01-17 | 2015-06-15 | Somalogic Inc | Multiplex Analyses of test samples |
| JP4698559B2 (ja) | 2006-11-24 | 2011-06-08 | Ｎｅｃソフト株式会社 | ウサギ由来のＩｇＧ抗体に結合性を有する核酸分子 |
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- 2000-07-24 WO PCT/US2000/020139 patent/WO2001009159A1/en not_active Ceased
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2006
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| EP1203007A4 (en) | 2003-06-04 |
| JP2003506024A (ja) | 2003-02-18 |
| EP1203007A1 (en) | 2002-05-08 |
| US20070010473A1 (en) | 2007-01-11 |
| EP1203007B1 (en) | 2009-04-15 |
| US6344321B1 (en) | 2002-02-05 |
| WO2001009159A1 (en) | 2001-02-08 |
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