CA2379165A1 - Chimeric proteins - Google Patents

Chimeric proteins Download PDF

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Publication number
CA2379165A1
CA2379165A1 CA002379165A CA2379165A CA2379165A1 CA 2379165 A1 CA2379165 A1 CA 2379165A1 CA 002379165 A CA002379165 A CA 002379165A CA 2379165 A CA2379165 A CA 2379165A CA 2379165 A1 CA2379165 A1 CA 2379165A1
Authority
CA
Canada
Prior art keywords
protein
interaction
nucleic acid
sequence
chimeric protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002379165A
Other languages
English (en)
French (fr)
Inventor
Christian Kilger
Michael Motz
Eva Loser
Manfred Kogl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sygnis Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2379165A1 publication Critical patent/CA2379165A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1252DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002379165A 1999-08-06 2000-08-07 Chimeric proteins Abandoned CA2379165A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19937230.6 1999-08-06
DE1999137230 DE19937230A1 (de) 1999-08-06 1999-08-06 Chimäre Proteine
PCT/DE2000/002657 WO2001011051A2 (de) 1999-08-06 2000-08-07 Chimäre proteine

Publications (1)

Publication Number Publication Date
CA2379165A1 true CA2379165A1 (en) 2001-02-15

Family

ID=7917496

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379165A Abandoned CA2379165A1 (en) 1999-08-06 2000-08-07 Chimeric proteins

Country Status (6)

Country Link
EP (1) EP1198571A2 (de)
JP (1) JP2003506089A (de)
AU (1) AU6983000A (de)
CA (1) CA2379165A1 (de)
DE (2) DE19937230A1 (de)
WO (1) WO2001011051A2 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7384739B2 (en) 2001-11-14 2008-06-10 Toyo Boseki Kabushiki Kaisha Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
US8232078B2 (en) 2001-11-28 2012-07-31 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
WO2023059361A1 (en) * 2021-10-06 2023-04-13 5Prime Biosciences, Inc. Polymerases for mixed aqueous-organic media and uses thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4722035B2 (ja) * 2003-03-25 2011-07-13 アジレント・テクノロジーズ・インク Dnaポリメラーゼ融合物およびその使用
US20190055527A1 (en) * 2015-11-27 2019-02-21 Kyushu University, National University Corporation Dna polymerase variant

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2734567B1 (fr) * 1995-05-26 1997-08-08 Commissariat Energie Atomique Proteines chimeriques activant la transcription par la polymerase iii, leur utilisation pour la detection et l'analyse des interactions entre proteines, et genes codant pour lesdites proteines
AU4159697A (en) * 1996-08-23 1998-03-06 President And Fellows Of Harvard College Interaction trap assay, reagents and uses thereof
WO1998045452A2 (en) * 1997-04-08 1998-10-15 The Rockfeller University Enzyme derived from thermophilic organisms that functions as a chromosomal replicase, and preparation and uses thereof
US6238905B1 (en) * 1997-09-12 2001-05-29 University Technology Corporation Thermophilic polymerase III holoenzyme
WO1999037661A1 (en) * 1998-01-27 1999-07-29 The Rockefeller University Dna replication proteins of gram positive bacteria and their use to screen for chemical inhibitors
DE19840771A1 (de) * 1998-08-06 2000-02-10 Lion Bioscience Ag Thermostabiler in vitro-Komplex mit Polymeraseaktivität
WO2000008164A2 (de) * 1998-08-06 2000-02-17 Lion Bioscience Ag Thermostabiler in vitro-komplex mit polymeraseaktivität

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7384739B2 (en) 2001-11-14 2008-06-10 Toyo Boseki Kabushiki Kaisha Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
US8232078B2 (en) 2001-11-28 2012-07-31 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
US8476045B2 (en) 2001-11-28 2013-07-02 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
US9139873B2 (en) 2001-11-28 2015-09-22 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
US9708598B2 (en) 2001-11-28 2017-07-18 Bio-Rad Laboratories, Inc. Methods of using improved polymerases
WO2023059361A1 (en) * 2021-10-06 2023-04-13 5Prime Biosciences, Inc. Polymerases for mixed aqueous-organic media and uses thereof

Also Published As

Publication number Publication date
DE10082298D2 (de) 2001-11-08
AU6983000A (en) 2001-03-05
DE19937230A1 (de) 2001-02-08
EP1198571A2 (de) 2002-04-24
WO2001011051A2 (de) 2001-02-15
JP2003506089A (ja) 2003-02-18
WO2001011051A3 (de) 2001-06-21

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Legal Events

Date Code Title Description
FZDE Discontinued