CA2375477A1 - Novel calpains and their use - Google Patents

Novel calpains and their use Download PDF

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Publication number
CA2375477A1
CA2375477A1 CA002375477A CA2375477A CA2375477A1 CA 2375477 A1 CA2375477 A1 CA 2375477A1 CA 002375477 A CA002375477 A CA 002375477A CA 2375477 A CA2375477 A CA 2375477A CA 2375477 A1 CA2375477 A1 CA 2375477A1
Authority
CA
Canada
Prior art keywords
leu
ser
gly
glu
asp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002375477A
Other languages
English (en)
French (fr)
Inventor
Neil T. Dear
Thomas Bohm
Achim Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2375477A1 publication Critical patent/CA2375477A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002375477A 1999-06-18 2000-06-07 Novel calpains and their use Abandoned CA2375477A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19928021.5 1999-06-18
DE19928021A DE19928021A1 (de) 1999-06-18 1999-06-18 Neue Calpaine und deren Verwendung
PCT/EP2000/005261 WO2000078933A2 (de) 1999-06-18 2000-06-07 Neue calpaine und deren verwendung

Publications (1)

Publication Number Publication Date
CA2375477A1 true CA2375477A1 (en) 2000-12-28

Family

ID=7911777

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002375477A Abandoned CA2375477A1 (en) 1999-06-18 2000-06-07 Novel calpains and their use

Country Status (18)

Country Link
EP (1) EP1185673A2 (no)
JP (1) JP2003503023A (no)
KR (1) KR20020011140A (no)
CN (1) CN1373808A (no)
AR (1) AR024573A1 (no)
AU (1) AU5970600A (no)
BG (1) BG106186A (no)
BR (1) BR0011721A (no)
CA (1) CA2375477A1 (no)
DE (1) DE19928021A1 (no)
HU (1) HUP0201800A2 (no)
IL (1) IL146940A0 (no)
MX (1) MXPA01012937A (no)
NO (1) NO20015922L (no)
PL (1) PL353004A1 (no)
SK (1) SK18262001A3 (no)
TR (1) TR200103662T2 (no)
WO (1) WO2000078933A2 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016336A1 (en) * 1999-09-02 2001-03-08 Lexicon Genetics Incorporated Human calcium dependent proteases and polynucleotides encoding the same
CN102939126B (zh) 2010-04-30 2015-09-16 雅培心脏血管系统股份有限公司 呈现迅速膨胀和收缩的改进型球囊导管

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737105A1 (de) * 1997-08-26 1999-03-04 Basf Ag Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'

Also Published As

Publication number Publication date
JP2003503023A (ja) 2003-01-28
WO2000078933A2 (de) 2000-12-28
AU5970600A (en) 2001-01-09
AR024573A1 (es) 2002-10-16
BR0011721A (pt) 2002-03-05
BG106186A (bg) 2002-12-29
NO20015922D0 (no) 2001-12-04
SK18262001A3 (sk) 2002-09-10
WO2000078933A3 (de) 2001-07-26
TR200103662T2 (tr) 2002-05-21
PL353004A1 (en) 2003-09-22
NO20015922L (no) 2002-02-12
KR20020011140A (ko) 2002-02-07
MXPA01012937A (es) 2002-07-30
IL146940A0 (en) 2002-08-14
CN1373808A (zh) 2002-10-09
HUP0201800A2 (en) 2002-09-28
DE19928021A1 (de) 2000-12-21
EP1185673A2 (de) 2002-03-13

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued