CA2373475C - Novel cyanine and indocyanine dye bioconjugates for biomedical applications - Google Patents

Novel cyanine and indocyanine dye bioconjugates for biomedical applications Download PDF

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Publication number
CA2373475C
CA2373475C CA2373475A CA2373475A CA2373475C CA 2373475 C CA2373475 C CA 2373475C CA 2373475 A CA2373475 A CA 2373475A CA 2373475 A CA2373475 A CA 2373475A CA 2373475 C CA2373475 C CA 2373475C
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CA
Canada
Prior art keywords
ch2och2
conh
compound
nhco
co2h
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2373475A
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English (en)
French (fr)
Other versions
CA2373475A1 (en
Inventor
Samuel Achilefu
Richard Bradley Dorshow
Joseph Edward Bugaj
Raghavan Rajagopalan
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Medibeacon Inc
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Medibeacon Inc
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Publication date
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Publication of CA2373475A1 publication Critical patent/CA2373475A1/en
Application granted granted Critical
Publication of CA2373475C publication Critical patent/CA2373475C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2373475A 1999-05-20 2000-04-26 Novel cyanine and indocyanine dye bioconjugates for biomedical applications Expired - Lifetime CA2373475C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13506099P 1999-05-20 1999-05-20
US60/135,060 1999-05-20
US09/325,769 1999-06-04
US09/325,769 US6217848B1 (en) 1999-05-20 1999-06-04 Cyanine and indocyanine dye bioconjugates for biomedical applications
PCT/US2000/011060 WO2000071162A2 (en) 1999-05-20 2000-04-26 Cyanine and indocyanine dye bioconjugates for biomedical applications

Publications (2)

Publication Number Publication Date
CA2373475A1 CA2373475A1 (en) 2000-11-30
CA2373475C true CA2373475C (en) 2012-10-23

Family

ID=26832945

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2373475A Expired - Lifetime CA2373475C (en) 1999-05-20 2000-04-26 Novel cyanine and indocyanine dye bioconjugates for biomedical applications

Country Status (11)

Country Link
US (1) US6217848B1 (https=)
EP (2) EP2058007A3 (https=)
JP (1) JP2003500367A (https=)
AT (1) ATE435662T1 (https=)
AU (1) AU4488800A (https=)
CA (1) CA2373475C (https=)
DE (1) DE60042522D1 (https=)
DK (1) DK1178830T3 (https=)
ES (1) ES2329542T3 (https=)
PT (1) PT1178830E (https=)
WO (1) WO2000071162A2 (https=)

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US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
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JPWO2011043061A1 (ja) * 2009-10-05 2013-03-04 キヤノン株式会社 光音響イメージング用造影剤、及び、それを用いた光音響イメージング方法
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JP5904602B2 (ja) 2011-09-05 2016-04-13 一般財団法人バイオダイナミックス研究所 高分子型蛍光分子プローブ
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JP6028096B2 (ja) 2012-06-21 2016-11-16 ノバダック テクノロジーズ インコーポレイテッド 血管造影及びかん流の定量化並びに解析手法
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CN107209118B (zh) 2014-09-29 2021-05-28 史赛克欧洲运营有限公司 在自体荧光存在下生物材料中目标荧光团的成像
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Also Published As

Publication number Publication date
EP2058007A2 (en) 2009-05-13
EP1178830A2 (en) 2002-02-13
EP2058007A3 (en) 2009-05-27
WO2000071162A3 (en) 2001-07-05
PT1178830E (pt) 2009-09-02
EP1178830B1 (en) 2009-07-08
ATE435662T1 (de) 2009-07-15
AU4488800A (en) 2000-12-12
US6217848B1 (en) 2001-04-17
CA2373475A1 (en) 2000-11-30
ES2329542T3 (es) 2009-11-27
DK1178830T3 (da) 2009-10-12
DE60042522D1 (de) 2009-08-20
WO2000071162A2 (en) 2000-11-30
JP2003500367A (ja) 2003-01-07

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Effective date: 20200426