CA2341143C - Production of motif-specific and context-independent antibodies using peptide libraries as antigens - Google Patents
Production of motif-specific and context-independent antibodies using peptide libraries as antigens Download PDFInfo
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- CA2341143C CA2341143C CA002341143A CA2341143A CA2341143C CA 2341143 C CA2341143 C CA 2341143C CA 002341143 A CA002341143 A CA 002341143A CA 2341143 A CA2341143 A CA 2341143A CA 2341143 C CA2341143 C CA 2341143C
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- motif
- peptide
- amino acid
- antibodies
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/148,712 US6441140B1 (en) | 1998-09-04 | 1998-09-04 | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
| US09/148,712 | 1998-09-04 | ||
| PCT/US1999/019597 WO2000014536A1 (en) | 1998-09-04 | 1999-08-26 | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2341143A1 CA2341143A1 (en) | 2000-03-16 |
| CA2341143C true CA2341143C (en) | 2006-11-21 |
Family
ID=22527002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002341143A Expired - Lifetime CA2341143C (en) | 1998-09-04 | 1999-08-26 | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US6441140B1 (enExample) |
| EP (3) | EP1850131B1 (enExample) |
| JP (5) | JP3732408B2 (enExample) |
| CA (1) | CA2341143C (enExample) |
| DE (1) | DE69936389T2 (enExample) |
| WO (1) | WO2000014536A1 (enExample) |
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| US7300753B2 (en) * | 1998-09-04 | 2007-11-27 | John Rush | Immunoaffinity isolation of modified peptides from complex mixtures |
| US20120244594A9 (en) * | 1998-09-04 | 2012-09-27 | Cell Signaling Technology, Inc. | Immunoaffinity isolation of modified peptides from complex mixtures |
| US9085609B2 (en) * | 1998-09-04 | 2015-07-21 | Cell Signaling Technology, Inc. | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
| US7198896B2 (en) * | 1998-09-04 | 2007-04-03 | Cell Signaling Technology, Inc. | Immunoaffinity isolation of modified peptides from complex mixtures |
| US6441140B1 (en) * | 1998-09-04 | 2002-08-27 | Cell Signaling Technology, Inc. | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
| US7208581B1 (en) * | 1999-11-05 | 2007-04-24 | The Burnham Institute | TRAF family proteins |
| WO2001049709A1 (en) * | 2000-01-03 | 2001-07-12 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Glycogen synthase kinase-3 inhibitors |
| CA2407945A1 (en) * | 2000-05-04 | 2001-11-08 | Mount Sinai Hospital | Molecules that modulate ubiquitin-dependent proteolysis and methods for identifying same |
| US20020102248A1 (en) * | 2000-09-06 | 2002-08-01 | The Government Of The United States Of America | Modulating response to genotoxic stress |
| WO2002077623A1 (fr) * | 2001-03-23 | 2002-10-03 | Japan Science And Technology Corporation | Sonde pour visualiser la phosphorylation/dephosphorylation de proteines et procede de detection et de quantification de la phosphorylation/dephosphorylation de proteines |
| US20110111424A1 (en) | 2001-06-21 | 2011-05-12 | Cell Signaling Technology, Inc. | Analysis of ubiquitinated polypeptides |
| DE02747916T1 (de) | 2001-06-21 | 2004-10-21 | Cell Signaling Technology, Inc., Beverly | Immunaffinitätsisolierung modifizierter peptide aus komplexen gemischen |
| US7378432B2 (en) | 2001-09-14 | 2008-05-27 | Tel Aviv University Future Technology Development L.P. | Glycogen synthase kinase-3 inhibitors |
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| GB0208104D0 (en) | 2002-04-09 | 2002-05-22 | Univ Dundee | Method |
| US7446092B2 (en) | 2002-12-12 | 2008-11-04 | Tel Aviv University Future Technology Development L.P. | Glycogen synthase kinase-3 inhibitors |
| CN1838954B (zh) * | 2003-06-27 | 2013-01-16 | 特拉维夫大学未来科技开发有限公司 | 糖原合酶激酶-3抑制剂 |
| JP2007502837A (ja) * | 2003-08-18 | 2007-02-15 | テシス バイオサイエンス， インコーポレイテッド | 小型エピトープ抗体を使用するサンプルの複雑さを低減するための方法 |
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| US9868781B2 (en) * | 2008-06-02 | 2018-01-16 | Cornell University | Antibodies for ubiquitinated proteins |
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| WO2011056561A1 (en) * | 2009-10-27 | 2011-05-12 | Beth Israel Deaconess Medical Center | Methods and compositions for the generation and use of conformation-specific antibodies |
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| CA2945263A1 (en) | 2014-04-09 | 2015-10-15 | Christopher Rudd | Use of gsk-3 inhibitors or activators which modulate pd-1 or t-bet expression to modulate t cell immunity |
| US10857243B2 (en) * | 2014-04-09 | 2020-12-08 | Brandeis University | Enzymatically responsive magnetic particles and their use |
| EP3137482A1 (en) | 2014-05-02 | 2017-03-08 | MorphoSys AG | Peptide libraries |
| US20210011025A1 (en) | 2015-11-11 | 2021-01-14 | Serimmune Inc. | Methods and compositions for assessing antibody specificities |
| EP3661958A2 (en) * | 2017-08-04 | 2020-06-10 | Abcam Plc | Methods and compositions for the development of antibodies specific to epitope post-translational modification status |
| US20230073946A1 (en) * | 2020-01-20 | 2023-03-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Affinity peptide conjugated with antioxidant for protection of proteins from oxidation |
| GB202012722D0 (en) * | 2020-08-14 | 2020-09-30 | Abcam Plc | Validation method |
| JP2023552662A (ja) * | 2020-12-07 | 2023-12-18 | ナックマイト ファーマシューティカルズ シーオー．エルティーディー． | ＲＸＲα結合剤及びＲＸＲα／ＰＬＫ１モジュレーター |
| CN116444677A (zh) * | 2023-06-09 | 2023-07-18 | 中国人民解放军军事科学院军事医学研究院 | 一种FoxM1蛋白Y575磷酸化的多克隆抗体及其制备方法和应用 |
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| JPS61227596A (ja) * | 1985-04-01 | 1986-10-09 | Fujisawa Pharmaceut Co Ltd | 抗リン酸化チロシンモノクロ−ナル抗体およびそれを産生するハイブリド−マ |
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| US6441140B1 (en) | 1998-09-04 | 2002-08-27 | Cell Signaling Technology, Inc. | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
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-
1998
- 1998-09-04 US US09/148,712 patent/US6441140B1/en not_active Expired - Lifetime
-
1999
- 1999-08-26 JP JP2000569230A patent/JP3732408B2/ja not_active Expired - Lifetime
- 1999-08-26 DE DE69936389T patent/DE69936389T2/de not_active Expired - Lifetime
- 1999-08-26 EP EP07012402A patent/EP1850131B1/en not_active Expired - Lifetime
- 1999-08-26 CA CA002341143A patent/CA2341143C/en not_active Expired - Lifetime
- 1999-08-26 EP EP10012547.5A patent/EP2325204B1/en not_active Expired - Lifetime
- 1999-08-26 WO PCT/US1999/019597 patent/WO2000014536A1/en not_active Ceased
- 1999-08-26 EP EP99945243A patent/EP1110086B1/en not_active Expired - Lifetime
-
2000
- 2000-03-24 US US09/535,364 patent/US6982318B1/en not_active Expired - Lifetime
-
2001
- 2001-11-13 US US10/014,485 patent/US7259022B2/en not_active Expired - Fee Related
-
2002
- 2002-05-07 US US10/139,841 patent/US7344714B2/en not_active Expired - Lifetime
- 2002-06-18 US US10/174,105 patent/US20030068652A1/en not_active Abandoned
-
2005
- 2005-09-08 JP JP2005260207A patent/JP5013693B2/ja not_active Expired - Lifetime
-
2012
- 2012-03-15 JP JP2012058996A patent/JP5648007B2/ja not_active Expired - Lifetime
-
2014
- 2014-02-27 JP JP2014036821A patent/JP2014132019A/ja not_active Withdrawn
-
2016
- 2016-06-07 JP JP2016113229A patent/JP2016210783A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20020132988A1 (en) | 2002-09-19 |
| JP5013693B2 (ja) | 2012-08-29 |
| JP2012162535A (ja) | 2012-08-30 |
| EP2325204B1 (en) | 2014-08-13 |
| JP2014132019A (ja) | 2014-07-17 |
| EP2325204A3 (en) | 2011-10-26 |
| DE69936389D1 (de) | 2007-08-09 |
| JP3732408B2 (ja) | 2006-01-05 |
| EP2325204A2 (en) | 2011-05-25 |
| JP2006036784A (ja) | 2006-02-09 |
| US7344714B2 (en) | 2008-03-18 |
| EP1110086A1 (en) | 2001-06-27 |
| US20020168684A1 (en) | 2002-11-14 |
| US20030068652A1 (en) | 2003-04-10 |
| US6441140B1 (en) | 2002-08-27 |
| EP1110086B1 (en) | 2007-06-27 |
| EP1110086A4 (en) | 2003-08-27 |
| DE69936389T2 (de) | 2008-02-28 |
| JP2016210783A (ja) | 2016-12-15 |
| US7259022B2 (en) | 2007-08-21 |
| WO2000014536A1 (en) | 2000-03-16 |
| EP1850131A1 (en) | 2007-10-31 |
| CA2341143A1 (en) | 2000-03-16 |
| US6982318B1 (en) | 2006-01-03 |
| EP1850131B1 (en) | 2013-01-23 |
| JP2002524092A (ja) | 2002-08-06 |
| JP5648007B2 (ja) | 2015-01-07 |
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