FR2757864B1 - Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique - Google Patents

Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique

Info

Publication number
FR2757864B1
FR2757864B1 FR9616207A FR9616207A FR2757864B1 FR 2757864 B1 FR2757864 B1 FR 2757864B1 FR 9616207 A FR9616207 A FR 9616207A FR 9616207 A FR9616207 A FR 9616207A FR 2757864 B1 FR2757864 B1 FR 2757864B1
Authority
FR
France
Prior art keywords
therapeutic
preparation
antibodies specifically
specifically recognizing
diagnostic use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9616207A
Other languages
English (en)
Other versions
FR2757864A1 (fr
Inventor
Jean Luc Chagnaud
Michel Geffard
Bernard Veyret
Philippe Vincendeau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9616207A priority Critical patent/FR2757864B1/fr
Priority to JP52968998A priority patent/JP2001508655A/ja
Priority to PCT/FR1997/002412 priority patent/WO1998029452A1/fr
Priority to EP97953005A priority patent/EP0948545A1/fr
Publication of FR2757864A1 publication Critical patent/FR2757864A1/fr
Application granted granted Critical
Publication of FR2757864B1 publication Critical patent/FR2757864B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9616207A 1996-12-30 1996-12-30 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique Expired - Lifetime FR2757864B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR9616207A FR2757864B1 (fr) 1996-12-30 1996-12-30 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique
JP52968998A JP2001508655A (ja) 1996-12-30 1997-12-23 特にニトロシル化タンパク質を識別する抗体、その調製法、治療および診断におけるその使用
PCT/FR1997/002412 WO1998029452A1 (fr) 1996-12-30 1997-12-23 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostic
EP97953005A EP0948545A1 (fr) 1996-12-30 1997-12-23 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9616207A FR2757864B1 (fr) 1996-12-30 1996-12-30 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique

Publications (2)

Publication Number Publication Date
FR2757864A1 FR2757864A1 (fr) 1998-07-03
FR2757864B1 true FR2757864B1 (fr) 1999-03-19

Family

ID=9499294

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9616207A Expired - Lifetime FR2757864B1 (fr) 1996-12-30 1996-12-30 Anticorps reconnaissant specifiquement une proteine nitrosylee, leur procede de preparation, leur utilisation therapeutique et diagnostique

Country Status (4)

Country Link
EP (1) EP0948545A1 (fr)
JP (1) JP2001508655A (fr)
FR (1) FR2757864B1 (fr)
WO (1) WO1998029452A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9085609B2 (en) 1998-09-04 2015-07-21 Cell Signaling Technology, Inc. Production of motif-specific and context-independent antibodies using peptide libraries as antigens
US6441140B1 (en) * 1998-09-04 2002-08-27 Cell Signaling Technology, Inc. Production of motif-specific and context-independent antibodies using peptide libraries as antigens
JP3453330B2 (ja) 1999-09-01 2003-10-06 シャープ株式会社 電子写真感光体
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
ES2335095T3 (es) * 2002-03-13 2010-03-22 Universite De Liege Deteccion de marcadores nitrados especificos.
AU2003299933B2 (en) * 2002-10-09 2010-06-24 Luoxis Diagnostics, Inc. Diagnosis and monitoring of inflammation, ischemia and appendicitis
US20150232540A1 (en) 2006-07-11 2015-08-20 Cell Signaling Technology, Inc. Analysis of ubiquitnated polypeptides
JP4935242B2 (ja) 2006-08-24 2012-05-23 ニプロ株式会社 脂肪酸を含有するｓ−ニトロソタンパク質とその製法
FR2926369A1 (fr) * 2008-01-10 2009-07-17 Univ Joseph Fourier Utilisation d'une proteine ou d'une sequence peptidique nitree pour la mise en oeuvre d'une methode de diagnostic

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835258A (en) * 1986-12-24 1989-05-30 Northwestsern University Conjugation of aromatic amines or nitro-containing compounds with proteins or polypeptides by photoirradiation of the azide derivatives with ultraviolet light in order to produce antibodies against the haptens
DE69332741T2 (de) * 1992-11-19 2003-10-02 The University Of Rochester, Rochester Nachweis von hypoxia
DE69433478T2 (de) * 1993-09-17 2004-11-25 Brigham And Women's Hospital, Boston Verwendung von stickoxid-addukten zur verhütung von thrombosen auf artifiziellen und vaskulären oberflächen
WO1996004311A1 (fr) * 1994-08-03 1996-02-15 University Of Alabama At Birmingham Research Foundation Anticorps monoclonal dirige contre la nitrotyrosine, procedes de diagnostic et procedes therapeutiques
EP0736770A3 (fr) * 1995-04-05 1997-05-02 Anda Biolog Sa Conjugué immunoréactif, procédé d'obtention de ce conjugué, anticorps dirigés contre ledit conjugué, composition pharmaceutique et dispositif de diagnostic les comprenant

Also Published As

Publication number Publication date
JP2001508655A (ja) 2001-07-03
WO1998029452A1 (fr) 1998-07-09
EP0948545A1 (fr) 1999-10-13
FR2757864A1 (fr) 1998-07-03

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