CA2331299A1 - Substituted guanidines and diaminonitroethenes, their preparation and use - Google Patents
Substituted guanidines and diaminonitroethenes, their preparation and use Download PDFInfo
- Publication number
- CA2331299A1 CA2331299A1 CA002331299A CA2331299A CA2331299A1 CA 2331299 A1 CA2331299 A1 CA 2331299A1 CA 002331299 A CA002331299 A CA 002331299A CA 2331299 A CA2331299 A CA 2331299A CA 2331299 A1 CA2331299 A1 CA 2331299A1
- Authority
- CA
- Canada
- Prior art keywords
- cyano
- trifluoromethyl
- guanidine
- bis
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 *c1cc(*)c(*)c(NC(N*)=*)c1 Chemical compound *c1cc(*)c(*)c(NC(N*)=*)c1 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK63498 | 1998-05-11 | ||
DK0634/98 | 1998-05-11 | ||
PCT/DK1999/000251 WO1999058497A1 (en) | 1998-05-11 | 1999-05-06 | Substituted guanidines and diaminonitroethenes, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2331299A1 true CA2331299A1 (en) | 1999-11-18 |
Family
ID=8095813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002331299A Abandoned CA2331299A1 (en) | 1998-05-11 | 1999-05-06 | Substituted guanidines and diaminonitroethenes, their preparation and use |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1077933A1 (de) |
JP (1) | JP2002514621A (de) |
AU (1) | AU3595799A (de) |
CA (1) | CA2331299A1 (de) |
WO (1) | WO1999058497A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6268284B1 (en) | 1998-10-07 | 2001-07-31 | Tokyo Electron Limited | In situ titanium aluminide deposit in high aspect ratio features |
MXPA03001535A (es) * | 2000-08-21 | 2004-12-13 | Pacific Corp | Derivados de tiourea novedosos y las composiciones farmaceuticas que contienen los mismos. |
CA2571717A1 (en) * | 2004-06-23 | 2006-01-05 | Josette-Nicole Mahy Gehenne | Compounds for the treatment of inflammation of the central nervous system |
PT3461834T (pt) | 2013-03-13 | 2021-09-10 | Sage Therapeutics Inc | Esteroides neuroativos |
CN108135911B (zh) | 2015-07-06 | 2021-06-25 | 萨奇治疗股份有限公司 | 氧甾醇及其使用方法 |
ES2921010T3 (es) | 2016-04-01 | 2022-08-16 | Sage Therapeutics Inc | Oxisteroles y procedimientos de uso de los mismos |
WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
PL3481846T3 (pl) | 2016-07-07 | 2021-12-20 | Sage Therapeutics, Inc. | 11-podstawione 24-hydroksysterole do stosowania w leczeniu stanów związanych z NMDA |
US11149056B2 (en) | 2016-09-30 | 2021-10-19 | Sage Therapeutics, Inc. | C7 substituted oxysterols and methods of use thereof |
JP2019532079A (ja) | 2016-10-18 | 2019-11-07 | セージ セラピューティクス, インコーポレイテッド | オキシステロールおよびその使用方法 |
US11149054B2 (en) | 2016-10-18 | 2021-10-19 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3232462A1 (de) * | 1982-09-01 | 1984-03-01 | Bayer Ag, 5090 Leverkusen | 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE3783529T2 (de) * | 1986-07-23 | 1993-05-13 | Hitachi Chemical Co Ltd | Optisches aufzeichnungsmedium. |
EP0310545A3 (de) * | 1987-09-02 | 1989-07-26 | Ciba-Geigy Ag | Cyanoguanidine als Härter für Epoxidharze |
JP2749639B2 (ja) * | 1989-06-28 | 1998-05-13 | 鐘紡株式会社 | シアノグアニジン誘導体 |
JPH0558985A (ja) * | 1991-08-29 | 1993-03-09 | Kanebo Ltd | シアノグアニジン誘導体の製造法 |
DK41193D0 (da) * | 1993-04-07 | 1993-04-07 | Neurosearch As | Ionkanalaabnere |
JP3270789B2 (ja) * | 1994-01-31 | 2002-04-02 | カネボウ株式会社 | 養毛剤 |
-
1999
- 1999-05-06 WO PCT/DK1999/000251 patent/WO1999058497A1/en not_active Application Discontinuation
- 1999-05-06 CA CA002331299A patent/CA2331299A1/en not_active Abandoned
- 1999-05-06 JP JP2000548301A patent/JP2002514621A/ja active Pending
- 1999-05-06 AU AU35957/99A patent/AU3595799A/en not_active Abandoned
- 1999-05-06 EP EP99917806A patent/EP1077933A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU3595799A (en) | 1999-11-29 |
JP2002514621A (ja) | 2002-05-21 |
EP1077933A1 (de) | 2001-02-28 |
WO1999058497A1 (en) | 1999-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |