CA2329777A1 - Antagonistes du recepteur ccr-3 - Google Patents
Antagonistes du recepteur ccr-3 Download PDFInfo
- Publication number
- CA2329777A1 CA2329777A1 CA002329777A CA2329777A CA2329777A1 CA 2329777 A1 CA2329777 A1 CA 2329777A1 CA 002329777 A CA002329777 A CA 002329777A CA 2329777 A CA2329777 A CA 2329777A CA 2329777 A1 CA2329777 A1 CA 2329777A1
- Authority
- CA
- Canada
- Prior art keywords
- propionate
- ethyl
- hydroxyphenyl
- sulfonylamino
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne des antagonistes du récepteur CCR-3, ainsi que de nouveaux procédés permettant d'utiliser ces antagonistes.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8322898P | 1998-04-27 | 1998-04-27 | |
US60/083,228 | 1998-04-27 | ||
PCT/US1999/009182 WO1999055324A1 (fr) | 1998-04-27 | 1999-04-27 | Antagonistes du recepteur ccr-3 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2329777A1 true CA2329777A1 (fr) | 1999-11-04 |
Family
ID=22177004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002329777A Abandoned CA2329777A1 (fr) | 1998-04-27 | 1999-04-27 | Antagonistes du recepteur ccr-3 |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1076557A1 (fr) |
JP (1) | JP2002512957A (fr) |
CA (1) | CA2329777A1 (fr) |
WO (1) | WO1999055324A1 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000041685A1 (fr) * | 1999-01-19 | 2000-07-20 | Smithkline Beecham Corporation | Antagonistes des recepteurs ccr-3 |
PL362711A1 (en) | 2000-09-29 | 2004-11-02 | Glaxo Group Limited | Morpholin-acetamide derivatives for the treatment of inflammatory diseases |
CA2445348A1 (fr) | 2001-04-27 | 2002-11-07 | Mitsubishi Pharma Corporation | Nouveaux composes de benzylpiperidine |
JP2003081937A (ja) * | 2001-09-07 | 2003-03-19 | Bayer Ag | ベンゼンスルホンアミド誘導体 |
EP2161254B1 (fr) | 2002-03-05 | 2014-08-13 | Sumitomo Chemical Company, Limited | Intermédiaire pour la préparation des composés biaryles |
SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
EP1507756B1 (fr) | 2002-05-24 | 2015-07-22 | Millennium Pharmaceuticals, Inc. | Inhibiteurs de ccr9 et utilisation de ceux-ci |
US7227035B2 (en) | 2002-11-18 | 2007-06-05 | Chemocentryx | Bis-aryl sulfonamides |
US7420055B2 (en) | 2002-11-18 | 2008-09-02 | Chemocentryx, Inc. | Aryl sulfonamides |
EP2256116A3 (fr) * | 2002-11-18 | 2011-11-16 | ChemoCentryx, Inc. | Arylsulfonamides |
US7741519B2 (en) | 2007-04-23 | 2010-06-22 | Chemocentryx, Inc. | Bis-aryl sulfonamides |
MXPA05009771A (es) | 2003-03-14 | 2005-10-26 | Ono Pharmaceutical Co | Derivados heterociclicos que contienen nitrogeno y medicamentos que los contienen como el ingrediente activo. |
PL1608374T3 (pl) | 2003-03-24 | 2009-08-31 | Axikin Pharmaceuticals Inc | 2-Fenoksy i 2-fenylosulfonoamidowe pochodne o aktywności antagonistycznej w stosunku do CCR3 do leczenia astmy i innych zaburzeń o podłożu zapalnym lub immunologicznym |
SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
EP2364982A1 (fr) | 2003-04-18 | 2011-09-14 | ONO Pharmaceutical Co., Ltd. | Dérivés de spiropipéridine comme antgonistes du recepteur chémokine et leur usage médical |
US7935700B2 (en) | 2004-09-08 | 2011-05-03 | Mitsubishi Tanabe Pharma Corporation | Morpholine compound |
TWI400232B (zh) | 2004-09-13 | 2013-07-01 | Ono Pharmaceutical Co | 含氮雜環衍生物及以該含氮雜環衍生物為有效成分之藥劑 |
EP1889622A4 (fr) | 2005-05-31 | 2009-12-23 | Ono Pharmaceutical Co | Compose de spiropiperidine et son utilisation medicinale |
WO2007011293A1 (fr) | 2005-07-21 | 2007-01-25 | Astrazeneca Ab | Nouveaux derives de piperidine |
DK1942108T3 (da) | 2005-10-28 | 2013-12-09 | Ono Pharmaceutical Co | Forbindelse indeholdende basisk gruppe samt anvendelse deraf |
PT1961744E (pt) | 2005-11-18 | 2013-05-15 | Ono Pharmaceutical Co | Composto que contém um grupo básico e sua utilização |
US8003642B2 (en) | 2006-03-10 | 2011-08-23 | Ono Pharmaceutical Co., Ltd. | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient |
EP2042503B1 (fr) | 2006-05-16 | 2013-01-30 | Ono Pharmaceutical Co., Ltd. | Composé ayant un groupe acide qui peut être protégé et utilisation dudit composé |
JP5245827B2 (ja) | 2006-07-31 | 2013-07-24 | 小野薬品工業株式会社 | スピロ結合した環状基を含有する化合物およびその用途 |
WO2010129351A1 (fr) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Procédé pour identifier et pour traiter une dégénérescence maculaire liée à l'âge |
TW201134820A (en) | 2010-03-17 | 2011-10-16 | Axikin Pharmaceuticals Inc | Arylsulfonamide CCR3 antagonists |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09255572A (ja) * | 1996-03-26 | 1997-09-30 | Takeda Chem Ind Ltd | ケモカイン受容体拮抗剤 |
-
1999
- 1999-04-27 WO PCT/US1999/009182 patent/WO1999055324A1/fr not_active Application Discontinuation
- 1999-04-27 CA CA002329777A patent/CA2329777A1/fr not_active Abandoned
- 1999-04-27 EP EP99920102A patent/EP1076557A1/fr not_active Withdrawn
- 1999-04-27 JP JP2000545523A patent/JP2002512957A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1076557A1 (fr) | 2001-02-21 |
JP2002512957A (ja) | 2002-05-08 |
WO1999055324A1 (fr) | 1999-11-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2329777A1 (fr) | Antagonistes du recepteur ccr-3 | |
AU2006212761B2 (en) | Combination therapy | |
US6420424B1 (en) | CCR-3 receptor antagonists | |
AU2013292046C1 (en) | Novel 5-aminotetrahydroquinoline-2-carboxylic acids and use thereof | |
EP1840122B1 (fr) | Composes d'aminopyrimidine et leurs sels, procede pour la preparation et l'utilisation pharmaceutique de ceux-ci | |
EP1763350B1 (fr) | Dérivés de nicotinamide et utilisation de ceux-ci comme agents thérapeutiques | |
EP1438298B1 (fr) | Derives de piperazine a activite antagoniste du recepteur ccr1 | |
US20100048660A1 (en) | Treatment of duchenne muscular dystrophy | |
JP2005501025A (ja) | 可溶性エポキシドヒドロラーゼ阻害薬の使用方法 | |
WO2000041685A1 (fr) | Antagonistes des recepteurs ccr-3 | |
WO2000053172A1 (fr) | Antagonistes du récepteur ccr-3 | |
AU2004305318A1 (en) | Methods of treating acute inflammation in animals with p38 MAP kinase inhibitors | |
WO2000027843A1 (fr) | Antagonistes du recepteur ccr3-3 | |
WO2000027835A1 (fr) | Antagonistes du recepteur ccr-3 | |
JP2003531856A (ja) | リン酸輸送阻害剤 | |
WO2000004003A1 (fr) | Antagonistes du recepteur ccr-3 | |
WO2000027800A1 (fr) | Antagonistes du recepteur ccr-3 | |
Wang et al. | Synthesis and immunosuppressant activity of pyrazole carboxamides | |
JPH0625193A (ja) | 中枢神経系に薬理活性をもつ化合物 | |
JP2000500454A (ja) | 血液調節化合物 | |
JP2000500467A (ja) | 血液調節化合物 | |
JP2024504002A (ja) | がんを処置する方法 | |
CN113582969A (zh) | 一种酰基硫脲类化合物在制备抗肠道病毒药物中的应用 | |
JP2003529600A (ja) | 新規なベンゾスルタムオキサゾリジノン抗菌剤 | |
JP2005509649A (ja) | 体内の金属の過剰の処置のための4−[3,5−ビス−(2−ヒドロキシ−フェニル)−[1,2,4]トリアゾール−1−イル]−安息香酸誘導体 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |