CA2319640C - Electrochemically reactive cathodes for an electrotransport device - Google Patents

Electrochemically reactive cathodes for an electrotransport device Download PDF

Info

Publication number
CA2319640C
CA2319640C CA002319640A CA2319640A CA2319640C CA 2319640 C CA2319640 C CA 2319640C CA 002319640 A CA002319640 A CA 002319640A CA 2319640 A CA2319640 A CA 2319640A CA 2319640 C CA2319640 C CA 2319640C
Authority
CA
Canada
Prior art keywords
electrode
cathodic
silver halide
body surface
electrolyte reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002319640A
Other languages
English (en)
French (fr)
Other versions
CA2319640A1 (en
Inventor
Lothar W. Kleiner
Erik R. Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CA2319640A1 publication Critical patent/CA2319640A1/en
Application granted granted Critical
Publication of CA2319640C publication Critical patent/CA2319640C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/4998Combined manufacture including applying or shaping of fluent material
    • Y10T29/49988Metal casting
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/4998Combined manufacture including applying or shaping of fluent material
    • Y10T29/49988Metal casting
    • Y10T29/49991Combined with rolling

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Discharge Lamp (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CA002319640A 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device Expired - Fee Related CA2319640C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7282398P 1998-01-28 1998-01-28
US7280698P 1998-01-28 1998-01-28
US60/072,823 1998-01-28
US60/072,806 1998-01-28
PCT/US1999/001748 WO1999038564A1 (en) 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device

Publications (2)

Publication Number Publication Date
CA2319640A1 CA2319640A1 (en) 1999-08-05
CA2319640C true CA2319640C (en) 2010-01-19

Family

ID=26753770

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002319640A Expired - Fee Related CA2319640C (en) 1998-01-28 1999-01-28 Electrochemically reactive cathodes for an electrotransport device

Country Status (12)

Country Link
US (1) US6505069B2 (enExample)
EP (1) EP1051219B1 (enExample)
JP (1) JP4221151B2 (enExample)
KR (1) KR100550492B1 (enExample)
CN (1) CN1147330C (enExample)
AT (1) ATE274973T1 (enExample)
AU (1) AU2346499A (enExample)
CA (1) CA2319640C (enExample)
DE (1) DE69919841T2 (enExample)
DK (1) DK1051219T3 (enExample)
ES (1) ES2229672T3 (enExample)
WO (1) WO1999038564A1 (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
IL154838A0 (en) * 2000-09-11 2003-10-31 Alza Corp Transdermal electrotransport device and method for manufacturing same
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7349733B2 (en) * 2001-11-02 2008-03-25 Ceramatel, Inc. Iontophoretic drug delivery systems
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
US7018345B2 (en) * 2002-12-06 2006-03-28 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis system
WO2006001022A1 (en) * 2004-06-28 2006-01-05 Power Paper Ltd Novel electrodes and uses thereof
JP4615929B2 (ja) * 2004-08-11 2011-01-19 久光製薬株式会社 イオントフォレーシス装置
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
WO2006055729A1 (en) * 2004-11-16 2006-05-26 Transcutaneous Technologies Inc. Iontophoretic device and method for administering immune response-enhancing agents and compositions
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
JPWO2007023907A1 (ja) * 2005-08-24 2009-02-26 Tti・エルビュー株式会社 冷凍型イオントフォレーシス用電極構造体
US20070048362A1 (en) * 2005-08-29 2007-03-01 Transcutaneous Technologies Inc. General purpose electrolyte solution composition for iontophoresis
US20100016781A1 (en) * 2005-08-29 2010-01-21 Mizuo Nakayama Iontophoresis device selecting drug to be administered on the basis of information form sensor
WO2007029611A1 (ja) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
JPWO2007032446A1 (ja) * 2005-09-15 2009-03-19 Tti・エルビュー株式会社 ロッド型イオントフォレーシス装置
JPWO2007032423A1 (ja) * 2005-09-16 2009-03-19 Tti・エルビュー株式会社 カテーテル型イオントフォレーシス装置
WO2007037324A1 (ja) * 2005-09-28 2007-04-05 Transcu Ltd. 乾燥型イオントフォレーシス用電極構造体
JP4902543B2 (ja) * 2005-09-30 2012-03-21 Tti・エルビュー株式会社 形状記憶セパレータを有するイオントフォレーシス用電極構造体およびそれを用いたイオントフォレーシス装置
EP1944057A4 (en) * 2005-09-30 2009-02-18 Tti Ellebeau Inc IONTOPHORESIS DEVICE FOR MONITORING THE DOSE AND TIME OF ADMINISTRATION OF A SLEEP-INDUCING AND ANALYTICAL AGENT
US20070074590A1 (en) * 2005-09-30 2007-04-05 Transcutaneous Technologies Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
JP2009509677A (ja) * 2005-09-30 2009-03-12 Tti・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
KR20080080087A (ko) * 2005-09-30 2008-09-02 티티아이 엘뷰 가부시키가이샤 신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
US20070078376A1 (en) * 2005-09-30 2007-04-05 Smith Gregory A Functionalized microneedles transdermal drug delivery systems, devices, and methods
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
BRPI0616771A2 (pt) * 2005-09-30 2011-06-28 Tti Ellebeau Inc dispositivo de iontoforese para liberar múltiplos agentes ativos para interfaces biológicas
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
JP4804904B2 (ja) * 2005-12-09 2011-11-02 Tti・エルビュー株式会社 イオントフォレーシス装置包装品
WO2007079116A1 (en) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US20080033398A1 (en) * 2005-12-29 2008-02-07 Transcutaneous Technologies Inc. Device and method for enhancing immune response by electrical stimulation
USD576282S1 (en) 2006-06-16 2008-09-02 Activatek, Inc. Adhesive transdermal medicament patch
MX2009002321A (es) * 2006-09-05 2009-03-23 Tti Ellebeau Inc Sistemas, dispositivos y metodos de suministro transdermico de farmacos que utilizan suministros de energia inductiva.
JP5383497B2 (ja) 2006-12-01 2014-01-08 Tti・エルビュー株式会社 装置、例として経皮送達装置に給電し且つ/又は当該装置を制御するシステム及び装置
US20080177219A1 (en) * 2007-01-23 2008-07-24 Joshi Ashok V Method for Iontophoretic Fluid Delivery
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US20080214985A1 (en) * 2007-02-02 2008-09-04 Activatek, Inc. Active transdermal medicament patch
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
JP2012529353A (ja) * 2009-06-09 2012-11-22 Tti・エルビュー株式会社 長寿命高容量電極、装置および製造方法
EP3001194B1 (en) * 2009-08-31 2019-04-17 Abbott Diabetes Care, Inc. Medical devices and methods
US9125625B2 (en) 2010-06-10 2015-09-08 The Regents Of The University Of California Textile-based printable electrodes for electrochemical sensing
US9159945B2 (en) 2012-12-13 2015-10-13 Universal Display Corporation System and method for matching electrode resistances in OLED light panels
US10898116B2 (en) * 2013-03-15 2021-01-26 Cambridge Medical Technologies LLC Methods of manufacture to optimize performance of transdermal sampling and analysis device
US10722160B2 (en) 2014-12-03 2020-07-28 The Regents Of The University Of California Non-invasive and wearable chemical sensors and biosensors
US12109032B1 (en) 2017-03-11 2024-10-08 Biolinq Incorporated Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure
US11045142B1 (en) 2017-04-29 2021-06-29 Biolinq, Inc. Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
EP4647772A3 (en) 2020-07-29 2025-12-24 Biolinq, Inc. Continuous analyte monitoring system with microneedle array
CA3184224A1 (en) 2021-05-08 2022-11-17 Joshua Ray Windmiller Fault detection for microneedle array based continuous analyte monitoring device
CN120857905A (zh) 2023-02-02 2025-10-28 比奥林公司 用于改善基于微针的连续分析物监测系统的传感器灵敏度的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110130A (en) * 1976-09-29 1978-08-29 Scm Corporation Forging powdered dispersion strengthened metal
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
JPS58197206A (ja) * 1982-04-30 1983-11-16 Hitachi Metals Ltd 高品位金属または合金粉末の製造方法
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4847980A (en) * 1987-11-16 1989-07-18 The Governors Of The University Of Alberta Method of manufacturing transmural cardiac electrodes
US5320597A (en) * 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5147297A (en) 1990-05-07 1992-09-15 Alza Corporation Iontophoretic delivery device
DK0575508T3 (da) * 1991-03-11 1994-11-14 Alza Corp Iontophoreseafgivelsesanordning og fremgangsmåde til fremstilling af samme
US5405317A (en) 1991-05-03 1995-04-11 Alza Corporation Iontophoretic delivery device
US5533971A (en) * 1993-09-03 1996-07-09 Alza Corporation Reduction of skin irritation during electrotransport
US5427736A (en) * 1994-04-05 1995-06-27 General Electric Company Method of making metal alloy foils
DE69532503T2 (de) * 1994-06-17 2004-11-04 Hisamitsu Pharmaceutical Co., Inc., Tosu Elektrode für iontophorese und vorrichtung dafür
WO1996009851A1 (en) * 1994-09-29 1996-04-04 Becton Dickinson And Company Method of preparing silver chloride electrodes for iontophoretic drug delivery devices
US5911919A (en) * 1997-09-08 1999-06-15 Integrated Thermal Sciences, Inc. Electron emission materials and components
US6190579B1 (en) * 1997-09-08 2001-02-20 Integrated Thermal Sciences, Inc. Electron emission materials and components

Also Published As

Publication number Publication date
EP1051219B1 (en) 2004-09-01
EP1051219A1 (en) 2000-11-15
DK1051219T3 (da) 2005-01-10
US20020055704A1 (en) 2002-05-09
WO1999038564A1 (en) 1999-08-05
JP2002501794A (ja) 2002-01-22
US6505069B2 (en) 2003-01-07
KR100550492B1 (ko) 2006-02-09
DE69919841D1 (de) 2004-10-07
CN1289260A (zh) 2001-03-28
CN1147330C (zh) 2004-04-28
DE69919841T2 (de) 2005-09-22
ES2229672T3 (es) 2005-04-16
AU2346499A (en) 1999-08-16
JP4221151B2 (ja) 2009-02-12
CA2319640A1 (en) 1999-08-05
ATE274973T1 (de) 2004-09-15
KR20010034445A (ko) 2001-04-25

Similar Documents

Publication Publication Date Title
CA2319640C (en) Electrochemically reactive cathodes for an electrotransport device
CA2319638C (en) Electrotransport electrode assembly having lower initial resistance
EP0522011B1 (en) Iontophoretic delivery device
US5503632A (en) Electrotransport device having improved cathodic electrode assembly
US5298017A (en) Layered electrotransport drug delivery system
US6169920B1 (en) Iontophoretic drug delivery apparatus
EP0527921B1 (en) Iontophoretic delivery device
US5162043A (en) Iontophoretic delivery device
EP0528789B1 (en) Device and method of iontophoretic drug delivery

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130128