CA2318394A1 - Novel antibacterial agents - Google Patents

Novel antibacterial agents Download PDF

Info

Publication number
CA2318394A1
CA2318394A1 CA002318394A CA2318394A CA2318394A1 CA 2318394 A1 CA2318394 A1 CA 2318394A1 CA 002318394 A CA002318394 A CA 002318394A CA 2318394 A CA2318394 A CA 2318394A CA 2318394 A1 CA2318394 A1 CA 2318394A1
Authority
CA
Canada
Prior art keywords
vancomycin
compound
formula
glycopeptide
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002318394A
Other languages
English (en)
French (fr)
Inventor
Qi-Qi Chen
John H. Griffin
Thomas E. Jenkins
J. Kevin Judice
Martin S. Linsell
Yongqui Mu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innoviva Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2318394A1 publication Critical patent/CA2318394A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002318394A 1998-02-20 1999-02-22 Novel antibacterial agents Abandoned CA2318394A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US7551498P 1998-02-20 1998-02-20
US60/075,514 1998-02-20
US7890398P 1998-03-20 1998-03-20
US60/078,903 1998-03-20
US8220998P 1998-04-17 1998-04-17
US60/082,209 1998-04-17
PCT/US1999/003850 WO1999042476A1 (en) 1998-02-20 1999-02-22 Novel antibacterial agents

Publications (1)

Publication Number Publication Date
CA2318394A1 true CA2318394A1 (en) 1999-08-26

Family

ID=27372700

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002318394A Abandoned CA2318394A1 (en) 1998-02-20 1999-02-22 Novel antibacterial agents

Country Status (7)

Country Link
EP (1) EP1060189A1 (de)
AR (1) AR019817A1 (de)
AU (1) AU3307399A (de)
CA (1) CA2318394A1 (de)
FR (1) FR2778184A1 (de)
IT (1) IT1307018B1 (de)
WO (1) WO1999042476A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230190B1 (hu) 1998-12-23 2015-09-28 Theravance, Inc Glikopeptidszármazékok és ezeket tartalmazó gyógyászati kompozíciók
KR100856479B1 (ko) 2000-05-02 2008-09-04 세라밴스 인코포레이티드 환원성 알킬화 방법
US6656694B2 (en) 2001-01-11 2003-12-02 Theravance, Inc. Method for identifying a ligand for a biological substrate
US20030158093A1 (en) * 2001-08-17 2003-08-21 Binyuan Sun Bifunctional glycopeptide antibiotics and combinatorial libararies thereof
TWI275594B (en) 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
TWI325323B (en) 2002-05-24 2010-06-01 Theravance Inc Cross-linked glycopeptide-cephalosporin antibiotics
DE602004024393D1 (de) 2003-05-23 2010-01-14 Theravance Inc Quervernetzte glycopeptid-cephalosporin-antibiotika
WO2005005436A2 (en) 2003-07-11 2005-01-20 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4159110B2 (ja) * 1996-04-12 2008-10-01 イーライ・リリー・アンド・カンパニー グリコペプチド化合物
AU2441697A (en) * 1996-04-12 1997-11-07 Eli Lilly And Company Covalently-linked glycopeptide dimers
US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides

Also Published As

Publication number Publication date
AU3307399A (en) 1999-09-06
AR019817A1 (es) 2002-03-20
WO1999042476A1 (en) 1999-08-26
EP1060189A1 (de) 2000-12-20
FR2778184A1 (fr) 1999-11-05
IT1307018B1 (it) 2001-10-23
ITTO990134A1 (it) 2000-08-22

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Legal Events

Date Code Title Description
FZDE Discontinued