FR2778184A1 - Composes a liaisons multiples antibacteriens nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Composes a liaisons multiples antibacteriens nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant Download PDF

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Publication number
FR2778184A1
FR2778184A1 FR9902172A FR9902172A FR2778184A1 FR 2778184 A1 FR2778184 A1 FR 2778184A1 FR 9902172 A FR9902172 A FR 9902172A FR 9902172 A FR9902172 A FR 9902172A FR 2778184 A1 FR2778184 A1 FR 2778184A1
Authority
FR
France
Prior art keywords
vancomycin
formula
group
glycopeptide
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR9902172A
Other languages
English (en)
French (fr)
Inventor
Qi Qi Chen
Jonh H Griffin
Thomas E Jenkins
J Kevin Judice
Martin S Linsell
Michael R Leadbetter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innoviva Inc
Original Assignee
Advanced Medicine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medicine Inc filed Critical Advanced Medicine Inc
Publication of FR2778184A1 publication Critical patent/FR2778184A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9902172A 1998-02-20 1999-02-22 Composes a liaisons multiples antibacteriens nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant Withdrawn FR2778184A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7551498P 1998-02-20 1998-02-20
US7890398P 1998-03-20 1998-03-20
US8220998P 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
FR2778184A1 true FR2778184A1 (fr) 1999-11-05

Family

ID=27372700

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9902172A Withdrawn FR2778184A1 (fr) 1998-02-20 1999-02-22 Composes a liaisons multiples antibacteriens nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (7)

Country Link
EP (1) EP1060189A1 (de)
AR (1) AR019817A1 (de)
AU (1) AU3307399A (de)
CA (1) CA2318394A1 (de)
FR (1) FR2778184A1 (de)
IT (1) IT1307018B1 (de)
WO (1) WO1999042476A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1249081C (zh) 1998-12-23 2006-04-05 施万制药 糖肽衍生物或含有它们的药物组合物
CA2407994C (en) 2000-05-02 2010-02-02 Advanced Medecine Inc. Reductive alkylation process
US6656694B2 (en) 2001-01-11 2003-12-02 Theravance, Inc. Method for identifying a ligand for a biological substrate
US20030158093A1 (en) * 2001-08-17 2003-08-21 Binyuan Sun Bifunctional glycopeptide antibiotics and combinatorial libararies thereof
TWI312785B (en) 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
TWI275594B (en) 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
TWI325323B (en) 2002-05-24 2010-06-01 Theravance Inc Cross-linked glycopeptide-cephalosporin antibiotics
WO2004113350A1 (en) 2003-05-23 2004-12-29 Theravance, Inc. Cross-linked glycopeptide - cephalosporin antibiotics
ES2302034T3 (es) 2003-07-11 2008-07-01 Theravance, Inc. Antibioticos de cefalosporina-glicopeptido reticulados.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0801075A1 (de) * 1996-04-12 1997-10-15 Eli Lilly And Company Kovalentgebundene Dimere von Glykopeptid-Antibiotika
EP0802199A2 (de) * 1996-04-12 1997-10-22 Eli Lilly And Company Kovalentgebundene Dimere von Glycopeptid-Antibiotika

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0801075A1 (de) * 1996-04-12 1997-10-15 Eli Lilly And Company Kovalentgebundene Dimere von Glykopeptid-Antibiotika
EP0802199A2 (de) * 1996-04-12 1997-10-22 Eli Lilly And Company Kovalentgebundene Dimere von Glycopeptid-Antibiotika
WO1997038706A1 (en) * 1996-04-12 1997-10-23 Eli Lilly And Company Glycopeptide compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
U N SUNDRAM ET AL.: "Novel vancomycin dimers against vancomyci-resistant enterococci", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 118, no. 51, 25 December 1996 (1996-12-25), AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., US, pages 13107 - 13108, XP002137432, ISSN: 0002-7863 *

Also Published As

Publication number Publication date
CA2318394A1 (en) 1999-08-26
AR019817A1 (es) 2002-03-20
AU3307399A (en) 1999-09-06
IT1307018B1 (it) 2001-10-23
EP1060189A1 (de) 2000-12-20
WO1999042476A1 (en) 1999-08-26
ITTO990134A1 (it) 2000-08-22

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Legal Events

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ST Notification of lapse