CA2317094A1 - Human protease molecules - Google Patents
Human protease molecules Download PDFInfo
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- CA2317094A1 CA2317094A1 CA002317094A CA2317094A CA2317094A1 CA 2317094 A1 CA2317094 A1 CA 2317094A1 CA 002317094 A CA002317094 A CA 002317094A CA 2317094 A CA2317094 A CA 2317094A CA 2317094 A1 CA2317094 A1 CA 2317094A1
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- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
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- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US09/008,271 | 1998-01-16 | ||
| US09/008,271 US6203979B1 (en) | 1998-01-16 | 1998-01-16 | Human protease molecules |
| PCT/US1999/000655 WO1999036550A2 (en) | 1998-01-16 | 1999-01-12 | Human protease molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2317094A1 true CA2317094A1 (en) | 1999-07-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002317094A Abandoned CA2317094A1 (en) | 1998-01-16 | 1999-01-12 | Human protease molecules |
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| US (1) | US6203979B1 (enExample) |
| EP (1) | EP1045913A2 (enExample) |
| JP (1) | JP2002508970A (enExample) |
| AU (1) | AU2113599A (enExample) |
| CA (1) | CA2317094A1 (enExample) |
| WO (1) | WO1999036550A2 (enExample) |
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| US6060587A (en) * | 1996-01-29 | 2000-05-09 | The Trustees Of The University Of Pennsylvania | Cellular receptor for HIV-1 VPR essential for G2/M phase transition of the cell cycle |
| US7732163B2 (en) * | 1997-08-21 | 2010-06-08 | Board Of Trustees Of The University Of Arkansas | Extracellular serine protease |
| EP0897986A3 (en) * | 1997-08-21 | 2000-07-05 | Smithkline Beecham Corporation | Aspartic proteinase 5 (ASP5) |
| US7157084B2 (en) * | 1997-08-21 | 2007-01-02 | The Board Of Trustees Of The University Of Arkansas System | Extracellular serine protease |
| US6642013B1 (en) * | 1997-08-21 | 2003-11-04 | The University Of Arkansas For Medical Sciences | Extracellular serine protease |
| US20030060612A1 (en) * | 1997-10-28 | 2003-03-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US7045333B1 (en) * | 1998-01-16 | 2006-05-16 | Incyte Corporation | Human protease molecules |
| US6140056A (en) * | 1999-01-27 | 2000-10-31 | Millennium Pharmaceuticals, Inc. | MSP-18 protein and nucleic acid molecules and uses therefor |
| US20020072089A1 (en) * | 1999-11-23 | 2002-06-13 | Holtzman Douglas A. | Novel ITALY, Lor-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor |
| AU2577699A (en) | 1998-02-06 | 1999-08-23 | Human Genome Sciences, Inc. | Human serine protease and serpin polypeptides |
| JPH11225765A (ja) * | 1998-02-13 | 1999-08-24 | Suntory Ltd | 新規セリンプロテアーゼ |
| CA2328138A1 (en) * | 1998-05-21 | 1999-11-25 | Diadexus Llc | A novel method of diagnosing, monitoring, and staging lung cancer |
| US6861215B1 (en) * | 1998-05-21 | 2005-03-01 | Diadexus, Inc. | Method of diagnosing, monitoring, and staging prostate cancer |
| US7160679B1 (en) * | 1998-05-21 | 2007-01-09 | Diadexus, Inc. | Method of diagnosing, monitoring, and staging lung cancer |
| US6902721B1 (en) * | 1998-07-10 | 2005-06-07 | Osteoscreen, Inc. | Inhibitors of proteasomal activity for stimulating bone growth |
| CA2341142A1 (en) * | 1998-09-02 | 2000-03-09 | Diadexus Llc | A novel method of diagnosing, monitoring, staging, imaging and treating various cancers |
| US6902892B1 (en) * | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| US7109292B2 (en) * | 1999-03-08 | 2006-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP2003506017A (ja) * | 1999-07-12 | 2003-02-18 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | セリパンクリン |
| MXPA02004046A (es) * | 1999-10-20 | 2002-10-11 | Univ Arkansas | Tadg-15: una serin proteasa extracelular sobre expresada en carcinomas. |
| US6677442B1 (en) * | 1999-10-29 | 2004-01-13 | University Of Kentucky Research Foundation | Nucleic acid encoding human REV1 protein |
| JP2003514524A (ja) | 1999-11-18 | 2003-04-22 | コルバス・インターナショナル・インコーポレイテッド | エントセリアーゼをコードしている核酸、エンドセリアーゼおよびその使用 |
| EP1244795A1 (en) * | 2000-01-06 | 2002-10-02 | Lexicon Genetics Incorporated | Novel human proteases and polynucleotides encoding the same |
| US6455668B1 (en) * | 2000-01-28 | 2002-09-24 | Eos Biotechnology, Inc. | Methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators |
| DE60143880D1 (de) * | 2000-02-03 | 2011-03-03 | Dendreon Corp | Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methoden |
| US6750034B1 (en) * | 2000-06-30 | 2004-06-15 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human serine protease D-G |
| AU2002236717A1 (en) * | 2001-01-08 | 2002-07-16 | Lexicon Genetics Incorporated | Human protease and polynucleotides encoding the same |
| WO2002072786A2 (en) | 2001-03-13 | 2002-09-19 | Corvas International, Inc. | Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon |
| CA2441378A1 (en) | 2001-03-22 | 2002-10-03 | Dendreon San Diego Llc | Nucleic acid molecules encoding serine protease cvsp14, the encoded polypeptides and methods based thereon |
| US6294368B1 (en) * | 2001-03-22 | 2001-09-25 | Applera Corporation | Isolated human metalloprotease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof |
| US7105333B2 (en) | 2001-03-27 | 2006-09-12 | Deadreon Corporation | Nucleic acid molecules encoding a transmembrane serine protease 9, the encoded polypeptides and methods based thereon |
| US20040236091A1 (en) * | 2001-03-28 | 2004-11-25 | Chicz Roman M. | Translational profiling |
| JP2005506832A (ja) | 2001-05-14 | 2005-03-10 | デンドレオン・サンディエゴ・リミテッド・ライアビリティ・カンパニー | トランスメンブランセリンプロテアーゼ10をコードする核酸分子、コードされるポリペプチドおよびそれに基づく方法 |
| US7196163B2 (en) * | 2001-05-22 | 2007-03-27 | Merk & Co., Inc. | Assays using amyloid precursor proteins with modified β-secretase cleavage sites to monitor β-secretase activity |
| EP1990057A1 (en) * | 2001-05-22 | 2008-11-12 | Merck & Co., Inc. | Beta-secretase substrates and uses thereof |
| JP2005511513A (ja) * | 2001-09-17 | 2005-04-28 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | 新規ヒトアミノプロテアーゼファミリーメンバー22417を使用する方法 |
| WO2003027145A1 (fr) * | 2001-09-26 | 2003-04-03 | Riken | Inducteur de mort cellulaire, cellules et animaux exprimant cet inducteur, et procede de criblage de medicament anti-mort cellulaire |
| WO2004006858A2 (en) * | 2002-07-15 | 2004-01-22 | Myriad Genetics, Inc | Compounds, compositions, and methods employing same |
| WO2005046573A2 (en) * | 2003-06-27 | 2005-05-26 | Diadexus, Inc. | Pro104 ANTIBODY COMPOSITIONS AND METHODS OF USE |
| US20070166715A1 (en) * | 2003-10-17 | 2007-07-19 | Stefan Golz | Diagnostics and therapeutics for diseases associated with aminopeptidase-like 1 (npepl1) |
| DE102004004924B4 (de) * | 2004-01-27 | 2007-04-26 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | A141S-und G399S-Mutation im Omi/HtrA2-Protein bei Morbus Parkinson |
| WO2006013012A2 (en) * | 2004-08-04 | 2006-02-09 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with napsin 1 (nap1) |
| WO2006013016A2 (en) * | 2004-08-04 | 2006-02-09 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with eosinophil serine protease 1 (prss21) |
| AU2005316169B2 (en) * | 2004-12-13 | 2011-11-17 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in the process of bone remodeling |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0828003A3 (en) | 1996-09-06 | 2003-01-15 | SmithKline Beecham plc | Human serine protease |
| EP0941320A2 (en) | 1996-11-13 | 1999-09-15 | Sagami Chemical Research Center | Human proteins having transmembrane domains and dnas encoding these proteins |
| DE69738653T2 (de) | 1996-11-20 | 2009-06-04 | Oklahoma Medical Research Foundation, Oklahoma | Klonierung und charakterisierung von napsin, einer aspartat-protease |
| WO1998056804A1 (en) | 1997-06-13 | 1998-12-17 | Human Genome Sciences, Inc. | 86 human secreted proteins |
| JP3809709B2 (ja) | 1997-07-16 | 2006-08-16 | 小野薬品工業株式会社 | 新規な好酸球セリンプロテアーゼ |
| US7014993B1 (en) | 1997-08-21 | 2006-03-21 | The Board Of Trustees Of The University Of Arkansas | Extracellular serine protease |
| JP2001516580A (ja) | 1997-09-17 | 2001-10-02 | ジェネンテック・インコーポレーテッド | 分泌性の、および膜貫通性のポリぺプチド、およびそれをコードする核酸 |
| DK1490386T3 (da) | 1998-03-10 | 2008-12-15 | Genentech Inc | Nyt polypeptid og nukleinsyrer kodende for dette |
| NZ510464A (en) | 1998-09-01 | 2004-05-28 | Genentech Inc | Further pro polypeptides and sequences thereof |
-
1998
- 1998-01-16 US US09/008,271 patent/US6203979B1/en not_active Expired - Lifetime
-
1999
- 1999-01-12 AU AU21135/99A patent/AU2113599A/en not_active Abandoned
- 1999-01-12 CA CA002317094A patent/CA2317094A1/en not_active Abandoned
- 1999-01-12 EP EP99901444A patent/EP1045913A2/en not_active Withdrawn
- 1999-01-12 WO PCT/US1999/000655 patent/WO1999036550A2/en not_active Ceased
- 1999-01-12 JP JP2000540252A patent/JP2002508970A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002508970A (ja) | 2002-03-26 |
| AU2113599A (en) | 1999-08-02 |
| EP1045913A2 (en) | 2000-10-25 |
| US6203979B1 (en) | 2001-03-20 |
| WO1999036550A2 (en) | 1999-07-22 |
| WO1999036550A3 (en) | 1999-11-18 |
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