AU2113599A - Human protease molecules - Google Patents

Human protease molecules

Info

Publication number
AU2113599A
AU2113599A AU21135/99A AU2113599A AU2113599A AU 2113599 A AU2113599 A AU 2113599A AU 21135/99 A AU21135/99 A AU 21135/99A AU 2113599 A AU2113599 A AU 2113599A AU 2113599 A AU2113599 A AU 2113599A
Authority
AU
Australia
Prior art keywords
human protease
protease molecules
molecules
human
protease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21135/99A
Other languages
English (en)
Inventor
Olga Bandman
Neil C. Corley
Karl J Guegler
Jennifer L. Hillman
Purvi Shah
Y. Tom Tang
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharmaceuticals Inc filed Critical Incyte Pharmaceuticals Inc
Publication of AU2113599A publication Critical patent/AU2113599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AU21135/99A 1998-01-16 1999-01-12 Human protease molecules Abandoned AU2113599A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/008,271 US6203979B1 (en) 1998-01-16 1998-01-16 Human protease molecules
US09008271 1998-01-16
PCT/US1999/000655 WO1999036550A2 (en) 1998-01-16 1999-01-12 Human protease molecules

Publications (1)

Publication Number Publication Date
AU2113599A true AU2113599A (en) 1999-08-02

Family

ID=21730708

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21135/99A Abandoned AU2113599A (en) 1998-01-16 1999-01-12 Human protease molecules

Country Status (6)

Country Link
US (1) US6203979B1 (enExample)
EP (1) EP1045913A2 (enExample)
JP (1) JP2002508970A (enExample)
AU (1) AU2113599A (enExample)
CA (1) CA2317094A1 (enExample)
WO (1) WO1999036550A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060587A (en) * 1996-01-29 2000-05-09 The Trustees Of The University Of Pennsylvania Cellular receptor for HIV-1 VPR essential for G2/M phase transition of the cell cycle
EP0897986A3 (en) * 1997-08-21 2000-07-05 Smithkline Beecham Corporation Aspartic proteinase 5 (ASP5)
US7157084B2 (en) * 1997-08-21 2007-01-02 The Board Of Trustees Of The University Of Arkansas System Extracellular serine protease
US6642013B1 (en) * 1997-08-21 2003-11-04 The University Of Arkansas For Medical Sciences Extracellular serine protease
US7732163B2 (en) * 1997-08-21 2010-06-08 Board Of Trustees Of The University Of Arkansas Extracellular serine protease
US20030060612A1 (en) * 1997-10-28 2003-03-27 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7045333B1 (en) * 1998-01-16 2006-05-16 Incyte Corporation Human protease molecules
US6140056A (en) * 1999-01-27 2000-10-31 Millennium Pharmaceuticals, Inc. MSP-18 protein and nucleic acid molecules and uses therefor
US20020072089A1 (en) * 1999-11-23 2002-06-13 Holtzman Douglas A. Novel ITALY, Lor-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor
WO1999040183A1 (en) 1998-02-06 1999-08-12 Human Genome Sciences, Inc. Human serine protease and serpin polypeptides
JPH11225765A (ja) * 1998-02-13 1999-08-24 Suntory Ltd 新規セリンプロテアーゼ
US6861215B1 (en) * 1998-05-21 2005-03-01 Diadexus, Inc. Method of diagnosing, monitoring, and staging prostate cancer
CA2328138A1 (en) * 1998-05-21 1999-11-25 Diadexus Llc A novel method of diagnosing, monitoring, and staging lung cancer
US7160679B1 (en) * 1998-05-21 2007-01-09 Diadexus, Inc. Method of diagnosing, monitoring, and staging lung cancer
US6902721B1 (en) * 1998-07-10 2005-06-07 Osteoscreen, Inc. Inhibitors of proteasomal activity for stimulating bone growth
ATE413466T1 (de) 1998-09-02 2008-11-15 Diadexus Inc Verfahren zur diagnose, bewertung sowie bilddarstellung verschiedener krebserkrankungen
US6902892B1 (en) * 1998-10-19 2005-06-07 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20030009013A1 (en) * 1998-12-30 2003-01-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2003506017A (ja) * 1999-07-12 2003-02-18 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング セリパンクリン
US20020151047A1 (en) * 2001-01-08 2002-10-17 Yi Hu Novel human protease and polynucleotides encoding the same
JP2003512036A (ja) * 1999-10-20 2003-04-02 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ アーカンソー Ｔａｄｇ−１５：癌において過剰発現されている細胞外セリンプロテアーゼ
US6677442B1 (en) * 1999-10-29 2004-01-13 University Of Kentucky Research Foundation Nucleic acid encoding human REV1 protein
AU784746B2 (en) 1999-11-18 2006-06-08 Dendreon Corporation Nucleic acids encoding endotheliases, endotheliases and uses thereof
JP2004502402A (ja) * 2000-01-06 2004-01-29 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトプロテアーゼおよびそれをコードするポリヌクレオチド
US6455668B1 (en) * 2000-01-28 2002-09-24 Eos Biotechnology, Inc. Methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators
AU2001233262A1 (en) * 2000-02-03 2001-08-14 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
US6750034B1 (en) 2000-06-30 2004-06-15 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding human serine protease D-G
US7125703B2 (en) 2001-03-13 2006-10-24 Dendreon Corporation Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
US6294368B1 (en) * 2001-03-22 2001-09-25 Applera Corporation Isolated human metalloprotease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
US7172892B2 (en) 2001-03-22 2007-02-06 Dendreon Corporation Nucleic acid molecules encoding serine protease CVSP14, the encoded polypeptides and methods based thereon
JP2005506047A (ja) 2001-03-27 2005-03-03 デンドレオン・サンディエゴ・リミテッド・ライアビリティ・カンパニー 膜貫通型セリンプロテアーゼ９をコード化する核酸分子、コード化されたポリペプチドおよびそれらに基づく方法
US20040236091A1 (en) * 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
US7112430B2 (en) 2001-05-14 2006-09-26 Dendreon Corporation Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
US7196163B2 (en) * 2001-05-22 2007-03-27 Merk & Co., Inc. Assays using amyloid precursor proteins with modified β-secretase cleavage sites to monitor β-secretase activity
US7132401B2 (en) * 2001-05-22 2006-11-07 Merck & Co., Inc. Beta-secretase substrates and uses thereof
JP2005511513A (ja) * 2001-09-17 2005-04-28 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 新規ヒトアミノプロテアーゼファミリーメンバー２２４１７を使用する方法
WO2003027145A1 (fr) * 2001-09-26 2003-04-03 Riken Inducteur de mort cellulaire, cellules et animaux exprimant cet inducteur, et procede de criblage de medicament anti-mort cellulaire
EP1542699A4 (en) * 2002-07-15 2009-03-25 Myriad Genetics Inc COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
CN1833020A (zh) * 2003-06-27 2006-09-13 迪亚德克瑟斯公司 Pro104抗体组合物及其使用方法
EP1687630A2 (en) * 2003-10-17 2006-08-09 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with aminopeptidase-like 1 (npepl1)
DE102004004924B4 (de) * 2004-01-27 2007-04-26 Eberhard-Karls-Universität Tübingen Universitätsklinikum A141S-und G399S-Mutation im Omi/HtrA2-Protein bei Morbus Parkinson
WO2006013016A2 (en) * 2004-08-04 2006-02-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with eosinophil serine protease 1 (prss21)
WO2006013012A2 (en) * 2004-08-04 2006-02-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with napsin 1 (nap1)
AU2005316169B2 (en) 2004-12-13 2011-11-17 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0828003A3 (en) * 1996-09-06 2003-01-15 SmithKline Beecham plc Human serine protease
US20030092175A1 (en) 1996-11-13 2003-05-15 Seishi Kato Human proteins having transmembrane domains and dnas encoding these proteins
DE69738653T2 (de) 1996-11-20 2009-06-04 Oklahoma Medical Research Foundation, Oklahoma Klonierung und charakterisierung von napsin, einer aspartat-protease
WO1998056804A1 (en) 1997-06-13 1998-12-17 Human Genome Sciences, Inc. 86 human secreted proteins
JP3809709B2 (ja) 1997-07-16 2006-08-16 小野薬品工業株式会社 新規な好酸球セリンプロテアーゼ
US7014993B1 (en) 1997-08-21 2006-03-21 The Board Of Trustees Of The University Of Arkansas Extracellular serine protease
NZ503343A (en) 1997-09-17 2002-09-27 Genentech Inc Secreted and transmembrane polypeptides and use to induce apoptosis of tumour cells
ES2312205T3 (es) 1998-03-10 2009-02-16 Genentech, Inc. Nuevo polipeptido y acidos nucleicos que lo codifican.
NZ510464A (en) 1998-09-01 2004-05-28 Genentech Inc Further pro polypeptides and sequences thereof

Also Published As

Publication number Publication date
CA2317094A1 (en) 1999-07-22
JP2002508970A (ja) 2002-03-26
WO1999036550A3 (en) 1999-11-18
WO1999036550A2 (en) 1999-07-22
US6203979B1 (en) 2001-03-20
EP1045913A2 (en) 2000-10-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase