CA2297723A1 - Synthesis of dihydrohonokiol compositions - Google Patents

Synthesis of dihydrohonokiol compositions Download PDF

Info

Publication number
CA2297723A1
CA2297723A1 CA002297723A CA2297723A CA2297723A1 CA 2297723 A1 CA2297723 A1 CA 2297723A1 CA 002297723 A CA002297723 A CA 002297723A CA 2297723 A CA2297723 A CA 2297723A CA 2297723 A1 CA2297723 A1 CA 2297723A1
Authority
CA
Canada
Prior art keywords
compound
och3
cooh
anxiety
diazepam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002297723A
Other languages
English (en)
French (fr)
Inventor
Rajiv K. Satsangi
William B. Stavinoha
Neera Satsangi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2297723A1 publication Critical patent/CA2297723A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/205—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
    • C07C39/21—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002297723A 1997-06-26 1998-06-26 Synthesis of dihydrohonokiol compositions Abandoned CA2297723A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5084597P 1997-06-26 1997-06-26
US60/050845 1997-06-26
PCT/US1998/013265 WO1999000346A1 (en) 1997-06-26 1998-06-26 Synthesis of dihydrohonokiol compositions

Publications (1)

Publication Number Publication Date
CA2297723A1 true CA2297723A1 (en) 1999-01-07

Family

ID=21967834

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002297723A Abandoned CA2297723A1 (en) 1997-06-26 1998-06-26 Synthesis of dihydrohonokiol compositions

Country Status (5)

Country Link
EP (1) EP0991614A1 (ja)
JP (1) JP2002507211A (ja)
AU (1) AU8168998A (ja)
CA (1) CA2297723A1 (ja)
WO (1) WO1999000346A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2358554A1 (en) * 1998-12-31 2000-07-13 Rajiv K. Satsangi Synthesis of dihydrohonokiol compositions
US20050070537A1 (en) 2002-10-10 2005-03-31 Chris Rundfeldt Use of dihydroimidazolones for the treatment of dogs
US20080300298A1 (en) * 2005-02-23 2008-12-04 Arbiser Jack L Honokiol Derivates For the Treatment of Proliferative Disorders
CN101279901B (zh) * 2007-12-25 2011-08-17 四川大学 和厚朴酚系列衍生物及其制备方法和用途
EP2423181A1 (en) 2010-07-28 2012-02-29 Prous Institute For Biomedical Research S.A. Multitarget substituted biphenyl diol derivatives
EP2986587B1 (en) 2013-04-17 2023-11-22 Sharon Anavi-Goffer Cb2 receptor ligands for the treatment of psychiatric disorders
US9820988B2 (en) 2014-03-24 2017-11-21 Boehringer Ingelheim Vetmedica Gmbh Treatment of epileptic disorders in feline animals
US11897910B2 (en) 2015-06-11 2024-02-13 The Medical College Of Wisconsin, Inc. Mito-honokiol compounds and methods of synthesis and use thereof
US10836782B2 (en) 2015-06-11 2020-11-17 The Medical College Of Wisconsin, Inc. Mito-honokiol compounds and methods of synthesis and use thereof
US10053406B2 (en) 2015-10-23 2018-08-21 Colgate-Palmolive Company Synthesis of honokiol
CA3149491A1 (en) * 2019-08-06 2021-02-11 Justin KIRKLAND Formulations including dihydrohonokiol
CN112125805B (zh) 2020-09-11 2022-10-18 北京红惠新医药科技有限公司 水溶性厚朴酚衍生物及和厚朴酚衍生物和其中间体的制备方法、和相关的单羟基保护中间体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5995229A (ja) * 1982-11-24 1984-06-01 Tsumura Juntendo Inc 新規ハイドロオキシビフエニル化合物
US5053548A (en) * 1989-02-08 1991-10-01 Otsuka Pharmaceutical Company, Ltd. Biphenyl derivative composition for nerve cell degeneration repairing or protective agent and process for preparing a phenyl derivative contained in the composition
US5449682A (en) * 1990-02-13 1995-09-12 Merck & Co., Inc. Angiotensin II antagonists incorporating a substituted benzyl element

Also Published As

Publication number Publication date
WO1999000346A8 (en) 2000-02-17
JP2002507211A (ja) 2002-03-05
WO1999000346A1 (en) 1999-01-07
EP0991614A1 (en) 2000-04-12
AU8168998A (en) 1999-01-19

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