CA2296093A1 - Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression - Google Patents
Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression Download PDFInfo
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- CA2296093A1 CA2296093A1 CA002296093A CA2296093A CA2296093A1 CA 2296093 A1 CA2296093 A1 CA 2296093A1 CA 002296093 A CA002296093 A CA 002296093A CA 2296093 A CA2296093 A CA 2296093A CA 2296093 A1 CA2296093 A1 CA 2296093A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/891,298 US6300488B1 (en) | 1997-07-10 | 1997-07-10 | Modified lepidopteran receptors and hybrid multifunctional proteins for use in transcription and regulation of transgene expression |
| US08/891,298 | 1997-07-10 | ||
| US9187498P | 1998-07-07 | 1998-07-07 | |
| US60/091,874 | 1998-07-07 | ||
| PCT/US1998/014215 WO1999002683A1 (en) | 1997-07-10 | 1998-07-10 | Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2296093A1 true CA2296093A1 (en) | 1999-01-21 |
Family
ID=26784430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002296093A Abandoned CA2296093A1 (en) | 1997-07-10 | 1998-07-10 | Modified lepidopteran receptors and hybrid multifunctional proteins for use in regulation of transgene expression |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0998560A1 (de) |
| AU (1) | AU738494B2 (de) |
| CA (1) | CA2296093A1 (de) |
| WO (1) | WO1999002683A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0103993A3 (en) | 1998-09-10 | 2003-10-28 | Pioneer Hi Bred Internat Inc D | Ecdysone receptors and methods for their use |
| GB9915126D0 (en) * | 1999-06-30 | 1999-09-01 | Imp College Innovations Ltd | Control of gene expression |
| AU3642601A (en) * | 1999-11-05 | 2001-05-30 | Avigen, Inc. | Ecdysone-inducible adeno-associated virus expression vectors |
| WO2001062780A1 (en) * | 2000-02-24 | 2001-08-30 | The Salk Institute For Biological Studies | Gene expression system based on chimeric receptors |
| US20040033600A1 (en) | 2001-03-21 | 2004-02-19 | Palli Subba Reddy | Ecdysone receptor-based inducible gene expression system |
| DE60122685T2 (de) | 2000-03-22 | 2007-08-23 | Rheogene Holdings Inc. | Induziertes genexpressionssystem basierend auf ecdysonrezeptoren |
| US8105825B2 (en) | 2000-10-03 | 2012-01-31 | Intrexon Corporation | Multiple inducible gene regulation system |
| AU2002251724B2 (en) | 2000-10-24 | 2007-06-21 | Syngenta Participations Ag | Control of gene expression in plants |
| US20030049689A1 (en) * | 2000-12-14 | 2003-03-13 | Cynthia Edwards | Multifunctional polypeptides |
| EP1373470B1 (de) | 2001-02-20 | 2013-04-24 | Intrexon Corporation | Neue substitutionsmutantenrezeptoren und ihre verwendung in einem induzierbaren genexpressionssystem auf basis eines nukleären rezeptors |
| ES2385598T3 (es) | 2001-02-20 | 2012-07-27 | Intrexon Corporation | Sistema novedoso de expresión génica inducible basado en el receptor de ecdisona/receptor X retinoide de invertebrado |
| WO2002066614A2 (en) | 2001-02-20 | 2002-08-29 | Rheogene Holdings, Inc. | Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system |
| DK1534738T3 (da) | 2001-02-20 | 2012-10-01 | Intrexon Corp | Nye substitutionsmutantreceptorer og anvendelse heraf i et inducérbart genekpressionssystem på basis af en nuklear receptor |
| US7919269B2 (en) | 2001-09-26 | 2011-04-05 | Intrexon Corporation | Whitefly ecdysone receptor nucleic acids, polypeptides, and uses thereof |
| JP2005532781A (ja) | 2001-09-26 | 2005-11-04 | レオジーン・ホールディングス，インコーポレーテッド | ヨコバイエクジソン受容体核酸、ポリペプチド、およびそれらの使用 |
| US7375093B2 (en) | 2002-07-05 | 2008-05-20 | Intrexon Corporation | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| US7304161B2 (en) | 2003-02-10 | 2007-12-04 | Intrexon Corporation | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
| US7456315B2 (en) | 2003-02-28 | 2008-11-25 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| US7935510B2 (en) | 2004-04-30 | 2011-05-03 | Intrexon Corporation | Mutant receptors and their use in a nuclear receptor-based inducible gene expression system |
| RU2490253C2 (ru) | 2007-05-29 | 2013-08-20 | Интрексон Корпорейшн | Хиральные диацилгидразиновые лиганды для модуляции экспрессии экзогенных генов с помощью экдизон-рецепторного комплекса |
| US8536354B2 (en) | 2008-03-14 | 2013-09-17 | Intrexon Corporation | Steroidal ligands and their use in gene switch modulation |
| US9127024B2 (en) | 2013-03-15 | 2015-09-08 | Intrexon Corporation | Boron-containing diacylhydrazines |
| US9944659B2 (en) | 2014-09-17 | 2018-04-17 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
| JP7288401B2 (ja) | 2017-01-10 | 2023-06-07 | プレシゲン，インコーポレイテッド | 新規の遺伝子スイッチ発現系を介したポリペプチドの発現のモジュレーション |
| IL306102A (en) | 2017-06-07 | 2023-11-01 | Precigen Inc | Expression of new cell markers |
| CN112135622A (zh) | 2018-03-06 | 2020-12-25 | 普莱西根股份有限公司 | 乙型肝炎疫苗及其用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU711391B2 (en) * | 1995-05-26 | 1999-10-14 | Syngenta Limited | A gene switch comprising an ecdysone receptor |
-
1998
- 1998-07-10 AU AU83895/98A patent/AU738494B2/en not_active Ceased
- 1998-07-10 CA CA002296093A patent/CA2296093A1/en not_active Abandoned
- 1998-07-10 EP EP98934353A patent/EP0998560A1/de not_active Withdrawn
- 1998-07-10 WO PCT/US1998/014215 patent/WO1999002683A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU738494B2 (en) | 2001-09-20 |
| AU8389598A (en) | 1999-02-08 |
| WO1999002683A1 (en) | 1999-01-21 |
| EP0998560A1 (de) | 2000-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |