CA2264802C - Antioxidant derived from lentil and its preparation and uses - Google Patents
Antioxidant derived from lentil and its preparation and uses Download PDFInfo
- Publication number
- CA2264802C CA2264802C CA002264802A CA2264802A CA2264802C CA 2264802 C CA2264802 C CA 2264802C CA 002264802 A CA002264802 A CA 002264802A CA 2264802 A CA2264802 A CA 2264802A CA 2264802 C CA2264802 C CA 2264802C
- Authority
- CA
- Canada
- Prior art keywords
- extract
- seed coat
- water soluble
- soluble extract
- coat according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 230000003078 antioxidant effect Effects 0.000 title abstract description 17
- 244000203494 Lens culinaris subsp culinaris Species 0.000 title abstract 2
- 239000003963 antioxidant agent Substances 0.000 title description 22
- 238000002360 preparation method Methods 0.000 title description 4
- 239000000284 extract Substances 0.000 claims abstract description 89
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 claims abstract description 14
- 241000219739 Lens Species 0.000 claims description 48
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 42
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims description 19
- 235000013824 polyphenols Nutrition 0.000 claims description 19
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims description 16
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- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 claims description 13
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- JPXMTWWFLBLUCD-UHFFFAOYSA-N nitro blue tetrazolium(2+) Chemical compound COC1=CC(C=2C=C(OC)C(=CC=2)[N+]=2N(N=C(N=2)C=2C=CC=CC=2)C=2C=CC(=CC=2)[N+]([O-])=O)=CC=C1[N+]1=NC(C=2C=CC=CC=2)=NN1C1=CC=C([N+]([O-])=O)C=C1 JPXMTWWFLBLUCD-UHFFFAOYSA-N 0.000 claims description 5
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
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- Food Science & Technology (AREA)
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- Immunology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/707,723 US5762936A (en) | 1996-09-04 | 1996-09-04 | Antioxidant derived from lentil and its preparation and uses |
| US08/707,723 | 1996-09-04 | ||
| PCT/US1997/015025 WO1998009526A1 (en) | 1996-09-04 | 1997-08-26 | Antioxidant derived from lentil and its preparation and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2264802A1 CA2264802A1 (en) | 1998-03-12 |
| CA2264802C true CA2264802C (en) | 2009-12-29 |
Family
ID=24842901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002264802A Expired - Lifetime CA2264802C (en) | 1996-09-04 | 1997-08-26 | Antioxidant derived from lentil and its preparation and uses |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5762936A (enExample) |
| EP (1) | EP0924986B1 (enExample) |
| JP (1) | JP2001500546A (enExample) |
| AT (1) | ATE395831T1 (enExample) |
| AU (1) | AU724720B2 (enExample) |
| CA (1) | CA2264802C (enExample) |
| DE (1) | DE69738712D1 (enExample) |
| WO (1) | WO1998009526A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6569446B1 (en) | 1996-09-20 | 2003-05-27 | The Howard Foundation | Solubilization of flavonols |
| TR199900626T2 (xx) * | 1996-09-20 | 1999-07-21 | The Howard Foundation | Flavonol i�eren besinler. |
| US6147070A (en) * | 1998-06-05 | 2000-11-14 | Facchini; Francesco | Methods and compositions for controlling iron stores to treat and cure disease states |
| US20020045580A1 (en) * | 1999-11-24 | 2002-04-18 | Sacks Meir S. | Compositions for raising uric acid levels and methods of using same |
| AU2175400A (en) * | 1998-12-11 | 2000-06-26 | Michigan State University | Method for the use of cherry isolates providing antioxidant phytoceutical or nutraceutical benefits |
| KR100441927B1 (ko) * | 1998-12-11 | 2004-07-30 | 미시간 스테이트 유니버시티 | 체리 단리물을 포함하는 뉴트라슈티칼 또는 파이토슈티칼의 잇점을 제공하는 배합물 |
| WO2000078326A1 (en) * | 1999-06-18 | 2000-12-28 | Dry Creek Nutrition, Inc. | Method and composition for preventing or treating adverse physiological effects associated with cardiac disease |
| US6221357B1 (en) * | 1999-09-02 | 2001-04-24 | Korea Research Institute Of Bioscience And Biotechnology | Flavonoids derived from citrus peels as collagen-induced platelet aggregation inhibitor |
| US7198924B2 (en) | 2000-12-11 | 2007-04-03 | Invitrogen Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
| US20030082647A1 (en) * | 2000-12-12 | 2003-05-01 | Reenan Robert A. | Transporter protein |
| JP2005506042A (ja) | 2000-12-12 | 2005-03-03 | ユニヴァーシティー オブ コネティカット | 細胞トランスポーターをコードするポリヌクレオチド、およびその使用方法 |
| WO2002054888A1 (en) * | 2001-01-10 | 2002-07-18 | Ganado Research, L.L.C. | Use of tannins and polymers to regulate digestion in animals |
| US6641851B2 (en) * | 2001-02-12 | 2003-11-04 | The Himalaya Drug Company | Herbal laxative preparation |
| US6753312B2 (en) * | 2001-07-12 | 2004-06-22 | Cyvex Technologies, Inc. | Food products and dietary supplements containing phenolated proteins and process for preparing the same |
| CA2357053A1 (en) * | 2001-09-04 | 2003-03-04 | Unknown | Effectiveness of a combination of antioxidant substances for the treatment of alzheimer's disease |
| US20040047945A1 (en) * | 2002-01-10 | 2004-03-11 | Bachman Stephen E. | Use of tannins and polymers to regulate digestion in animals |
| WO2004080993A1 (ja) * | 2003-03-11 | 2004-09-23 | Toyo Shinyaku Co., Ltd. | プロアントシアニジン高含有物の製造方法 |
| ITMI20031311A1 (it) * | 2003-06-27 | 2004-12-28 | Indena Spa | Formulazioni per il trattamento di disturbi artrosici. |
| US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
| CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
| TW200505468A (en) * | 2003-08-11 | 2005-02-16 | Suntory Ltd | Agent for improving hepato-bililary dysfunction |
| CZ13908U1 (cs) * | 2003-10-08 | 2004-01-05 | Cpn Spol. S R.O. | Kosmetický přípravek s vysokomolekulární antioxidační složkou |
| DE602004027538D1 (de) | 2003-12-01 | 2010-07-15 | Life Technologies Corp | Rekombinationsstellen enthaltende nukleinsäuremoleküle und verfahren zur verwendung davon |
| FR2863454B1 (fr) * | 2003-12-12 | 2006-04-07 | Gervais Danone Sa | Produits cerealiers possedant un fort pouvoir anti-oxydant |
| MXPA06013137A (es) | 2004-05-10 | 2007-05-16 | Itesm | Inhibicion del crecimiento celular cancerigenos a traves de extractos de frijol negro (phaseolus vulgarisl). |
| KR100659945B1 (ko) * | 2005-02-28 | 2006-12-22 | 뉴트라팜주식회사 | 천연용매를 추출매체로 하는 소나무류 수피 유래 항산화성물질 추출방법 및 이에 의한 항산화성 추출물 |
| US8124135B2 (en) * | 2005-05-24 | 2012-02-28 | Vdf Futureceuticals, Inc. | Compositions and methods for reduction of LDL oxidation |
| RU2302423C2 (ru) * | 2005-06-10 | 2007-07-10 | Закрытое акционерное общество "Научно-производственное объединение "ТЕХКОН" | Способ выделения биологически активных антоцианов |
| JPWO2007010911A1 (ja) * | 2005-07-15 | 2009-01-29 | 株式会社東洋新薬 | 外傷の軽減および回復促進剤 |
| US7757697B2 (en) * | 2005-12-22 | 2010-07-20 | Swisher International, Inc. | Method for reducing nitrosamines in tobacco |
| US20070189990A1 (en) * | 2006-02-16 | 2007-08-16 | Anthony East | Ultraviolet absorber for cosmetics and polymeric materials |
| JP2008184441A (ja) * | 2007-01-30 | 2008-08-14 | B & C Laboratories Inc | 細胞増殖促進用皮膚外用剤 |
| AU2011211461B2 (en) * | 2008-01-11 | 2011-11-17 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Chia seed composition |
| US20090181114A1 (en) * | 2008-01-11 | 2009-07-16 | U.S. Nutraceuticals, Llc D/B/A Valensa International | Chia seed beverage and related method |
| US8445200B2 (en) | 2009-04-15 | 2013-05-21 | The Regents Of The University Of California | Genotoxicity as a biomarker for inflammation |
| CN102138961A (zh) * | 2010-02-02 | 2011-08-03 | 北京绿色金可生物技术股份有限公司 | 黑豆皮提取物在预防和治疗骨关节炎的产品中的应用 |
| US9029518B2 (en) | 2012-06-27 | 2015-05-12 | King Saud University | Method of extracting kaempferol-based antioxidants from Solenostemma arghel |
| US9828641B2 (en) | 2013-08-01 | 2017-11-28 | The Regents Of The University Of California | Systemic genotoxicity as blood marker for allergic inflammation |
| ITUB20154965A1 (it) | 2015-11-05 | 2017-05-05 | Univ Degli Studi Di Camerino | Estratto di lenticchie con azione ipocolesterolemizzante e prebiotica |
| KR101742888B1 (ko) * | 2015-12-15 | 2017-06-01 | 계명대학교 산학협력단 | 벨루가 렌틸콩 추출물을 포함하는 간 손상 예방 또는 치료용 조성물 |
| US20180022983A1 (en) * | 2016-07-19 | 2018-01-25 | Baker Hughes, A Ge Company, Llc | Flavonoid and plant phenolic acid additives for downhole fluids |
| CN113387988A (zh) * | 2021-05-12 | 2021-09-14 | 安徽工程大学 | 一种白扁豆花黄酮类化合物分离制备方法及用途 |
| CN113412857A (zh) * | 2021-06-28 | 2021-09-21 | 北京市农林科学院 | 一种含原儿茶酸酯的果蔬杀菌保鲜剂 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281233A (en) * | 1977-05-03 | 1981-07-28 | Ceskoslovenska Akademie Ved | Hydrophilic macroporous three dimensional copolymers of hydroxyalkyl acrylates or methacrylates with crosslinking agents and the method of their manufacturing |
| JPS6116982A (ja) * | 1984-07-03 | 1986-01-24 | Kikkoman Corp | 抗酸化剤 |
| US4530844A (en) * | 1984-07-26 | 1985-07-23 | Warner-Lambert Company | Synergistic non-steroidal anti-inflammatory compounds and compositions thereof |
| US4698360B1 (en) * | 1985-04-09 | 1997-11-04 | D Investigations Pharmacologiq | Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof |
| US4755504A (en) * | 1985-10-03 | 1988-07-05 | Yaguang Liu | Pharmaceutical composition from Tienchi |
| JPH0825890B2 (ja) * | 1987-06-18 | 1996-03-13 | 呉羽化学工業株式会社 | 抗ウイルス剤 |
| DE4141866C1 (enExample) * | 1991-12-18 | 1993-01-28 | Mucos Emulsionsgesellschaft Mbh, 1000 Berlin, De | |
| JPH07506822A (ja) * | 1992-05-19 | 1995-07-27 | ノボゲン リサーチ ピーティーワイ リミッテッド | フィト−エストロゲン，類似体またはその代謝産物を含有する健康補助剤 |
-
1996
- 1996-09-04 US US08/707,723 patent/US5762936A/en not_active Expired - Lifetime
-
1997
- 1997-08-26 JP JP10512720A patent/JP2001500546A/ja not_active Ceased
- 1997-08-26 CA CA002264802A patent/CA2264802C/en not_active Expired - Lifetime
- 1997-08-26 WO PCT/US1997/015025 patent/WO1998009526A1/en not_active Ceased
- 1997-08-26 DE DE69738712T patent/DE69738712D1/de not_active Expired - Lifetime
- 1997-08-26 AU AU41633/97A patent/AU724720B2/en not_active Ceased
- 1997-08-26 AT AT97939572T patent/ATE395831T1/de not_active IP Right Cessation
- 1997-08-26 EP EP97939572A patent/EP0924986B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0924986A1 (en) | 1999-06-30 |
| AU724720B2 (en) | 2000-09-28 |
| JP2001500546A (ja) | 2001-01-16 |
| ATE395831T1 (de) | 2008-06-15 |
| EP0924986B1 (en) | 2008-05-21 |
| US5762936A (en) | 1998-06-09 |
| CA2264802A1 (en) | 1998-03-12 |
| EP0924986A4 (en) | 2002-11-27 |
| WO1998009526A1 (en) | 1998-03-12 |
| DE69738712D1 (de) | 2008-07-03 |
| AU4163397A (en) | 1998-03-26 |
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